Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Olivia Kugler-Umana"'
Autor:
Priyadharshini Devarajan, Allen M. Vong, Catherine H. Castonguay, Noah J. Silverstein, Olivia Kugler-Umana, Bianca L. Bautista, Karen A. Kelly, Jeremy Luban, Susan L. Swain
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113429- (2023)
Externí odkaz:
https://doaj.org/article/370f4f484e794576b3fda940ba2c76b5
Autor:
Priyadharshini Devarajan, Michael C. Jones, Olivia Kugler-Umana, Allen M. Vong, Jingya Xia, Susan L. Swain
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Although much is known about the mechanisms by which pathogen recognition drives the initiation of T cell responses, including those to respiratory viruses, the role of pathogen recognition in fate decisions of T cells once they have become effectors
Externí odkaz:
https://doaj.org/article/94f01bb1f2b24378aa6b61f63e808112
Autor:
Olivia Kugler‐Umana, Wenliang Zhang, Yi Kuang, Jialing Liang, Catherine H. Castonguay, Susan L. Tonkonogy, Ann Marshak‐Rothstein, Priyadharshini Devarajan, Susan L. Swain
Publikováno v:
Aging Cell. 21
Autor:
Olivia, Kugler-Umana, Wenliang, Zhang, Yi, Kuang, Jialing, Liang, Catherine H, Castonguay, Susan L, Tonkonogy, Ann, Marshak-Rothstein, Priyadharshini, Devarajan, Susan L, Swain
Publikováno v:
Aging cell. 21(10)
Age-associated B cells (ABC) accumulate with age and are associated with autoimmunity and chronic infection. However, their contributions to acute infection in the aged and their developmental pathways are unclear. We find that the response against i
Publikováno v:
Crit Rev Immunol
In humans and mice, susceptibility to infections and autoimmunity increases with age due to age-associated changes in innate and adaptive immune responses. Aged innate cells are also less active, leading to decreased naive T- and B-cell responses. Ag
Autor:
Priyadharshini Devarajan, Allen M. Vong, Catherine H. Castonguay, Olivia Kugler-Umana, Bianca L. Bautista, Michael C. Jones, Karen A. Kelly, Jingya Xia, Susan L. Swain
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance Influenza infection elicits strong, long-lived protective antibodies, but most current influenza vaccines give weaker, short-lived protection. We noted that live virus is still replicating, making antigen and causing inflammation at 7 d
Autor:
Olivia Kugler-Umana, Wenliang Zhang, Yi Kuang, Jialing Liang, Catherine H. Castonguay, Susan L. Tonkonogy, Ann Marshak-Rothstein, Priyadharshini Devarajan, Susan L. Swain
Age-associated B cells (ABC) accumulate with age and are associated with autoimmunity and chronic infection. However, their contributions to acute infection in the aged and their developmental pathways are unclear. We find that the response against i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::730b98083fa3e531fd9c258d29d30143
https://doi.org/10.1101/2022.02.04.479159
https://doi.org/10.1101/2022.02.04.479159
Autor:
Priyadharshini, Devarajan, Allen M, Vong, Catherine H, Castonguay, Olivia, Kugler-Umana, Bianca L, Bautista, Michael C, Jones, Karen A, Kelly, Jingya, Xia, Susan L, Swain
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(8)
While influenza infection induces robust, long-lasting, antibody responses and protection, including the T follicular helper cells (T
Publikováno v:
Front Aging
As mice age their adaptive immune system changes dramatically, leading to weakened responses to newly encountered antigens and poor efficacy of vaccines. A shared pattern emerges in the aged, with both CD4 T and B cell responses requiring higher leve
Autor:
Priyadharshini Devarajan, Allen M Vong, Catherine H Castonguay, Bianca L Bautista, Michael C Jones, Olivia Kugler-Umana, Susan L Swain
Publikováno v:
The Journal of Immunology. 206:103.11-103.11
Functionally specialized, tissue-restricted CD4 effector subsets such as T helper cytotoxic cells (ThCTL) in the infected tissue and T follicular helper cells (TFH) in secondary lymphoid organs develop after Th1 and other effectors. Following influen