Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Olivia K. Ottone"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/bcd041b4f2454d9699435c1ffd0ed3d7
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The DNA-sensing cGAS-STING pathway promotes the senescence-associated secretory phenotype (SASP) and mediates type-I interferon inflammatory responses to foreign viral and bacterial DNA as well as self-DNA. Studies of the intervertebral disc in human
Externí odkaz:
https://doaj.org/article/81fd50386e5a47cd8389486e7d748014
Autor:
Maria Tsingas, Ruteja A. Barve, Véronique Lefebvre, Makarand V. Risbud, Olivia K. Ottone, Abdul Haseeb, Irving M. Shapiro
Publikováno v:
Matrix Biol
SOX9 plays an important role in chondrocyte differentiation and, in the developing axial skeleton, maintains the notochord and the demarcation of intervertebral disc compartments. Diminished expression is linked to campomelic dysplasia, resulting in
Publikováno v:
J Bone Miner Res
The inflammatory cytokine tumor necrosis factor alpha (TNFα) is considered to play a key role in the pathogenesis of intervertebral disc disease. To evaluate the importance of this cytokine we examined the inflammatory environment and spinal phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7c1b91c4a8f6e5732a6865bc9ce60c
https://europepmc.org/articles/PMC7145745/
https://europepmc.org/articles/PMC7145745/
Autor:
Irving M. Shapiro, Victoria A. Tran, Emanuel J. Novais, Steven Tessier, Michael J. DiMuzio, Makarand V. Risbud, Olivia K. Ottone, Alexandra C. Doolittle
Publikováno v:
Matrix Biol
The tonicity-responsive enhancer binding protein (TonEBP) plays an important role in intervertebral disc and axial skeleton embryogenesis. However, the contribution of this osmoregulatory transcription factor in postnatal intervertebral disc homeosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30bad5b0dbe7868f6800435b05d8fe7f
https://europepmc.org/articles/PMC7078052/
https://europepmc.org/articles/PMC7078052/