Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Olivia K. Burn"'
Autor:
Anna H. Mooney, Sarah L. Draper, Olivia K. Burn, Regan J. Anderson, Benjamin J. Compton, Chingwen Tang, Kathryn J. Farrand, Pietro Di Lucia, Micol Ravà, Valeria Fumagalli, Leonardo Giustini, Elisa Bono, Dale I. Godfrey, William R. Heath, Weiming Yuan, Francis V. Chisari, Luca G. Guidotti, Matteo Iannacone, John Sidney, Alessandro Sette, Shivali A. Gulab, Gavin F. Painter, Ian F. Hermans
Publikováno v:
JHEP Reports, Vol 6, Iss 5, Pp 101038- (2024)
Background & Aims: Liver diseases resulting from chronic HBV infection are a significant cause of morbidity and mortality. Vaccines that elicit T-cell responses capable of controlling the virus represent a treatment strategy with potential for long-t
Externí odkaz:
https://doaj.org/article/ee2629abc47b4a819f89b5234ea4bfff
Autor:
Kef K Prasit, Laura Ferrer-Font, Olivia K Burn, Regan J Anderson, Benjamin J Compton, Alfonso J Schmidt, Johannes U Mayer, Chun-Jen J Chen, Nathaniel Dasyam, David S Ritchie, Dale I Godfrey, Stephen R Mattarollo, P Rod Dunbar, Gavin F Painter, Ian F Hermans
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Intratumoural administration of unmethylated cytosine-phosphate-guanine motifs (CpG) to stimulate toll-like receptor (TLR)-9 has been shown to induce tumour regression in preclinical studies and some efficacy in the clinic. Because activated natural
Externí odkaz:
https://doaj.org/article/423fa268183140eca4c64e8a2ff85aed
Autor:
Olivia K Burn, Kathryn Farrand, Tara Pritchard, Sarah Draper, Ching‐wen Tang, Anna H Mooney, Alfonso J Schmidt, Sung H Yang, Geoffrey M Williams, Margaret A Brimble, Matheswaran Kandasamy, Andrew J Marshall, Kate Clarke, Gavin F Painter, Ian F Hermans, Robert Weinkove
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 7, Pp n/a-n/a (2022)
Abstract Objectives Metastasis is the principal cause of breast cancer mortality. Vaccines targeting breast cancer antigens have yet to demonstrate clinical efficacy, and there remains an unmet need for safe and effective treatment to reduce the risk
Externí odkaz:
https://doaj.org/article/3c9b77a20a6e4b3da7b8452985eb9f84
Autor:
Nathaniel Dasyam, Katrina J. Sharples, Catherine Barrow, Ying Huang, Evelyn Bauer, Brigitta Mester, Catherine E. Wood, Astrid Authier-Hall, Marina Dzhelali, Tess Ostapowicz, Rajiv Kumar, Jessica Lowe, Alice Maxwell, Olivia K. Burn, Geoffrey M. Williams, Sarah E. Carley, Graham Caygill, Jeremy Jones, Susanna T. S. Chan, Victoria A. Hinder, Jerome Macapagal, Monica McCusker, Robert Weinkove, Margaret A. Brimble, Gavin F. Painter, Michael P. Findlay, P. Rod Dunbar, Olivier Gasser, Ian F. Hermans
Publikováno v:
Cancer Immunology, Immunotherapy.
Aim We have previously reported that polyfunctional T cell responses can be induced to the cancer testis antigen NY-ESO-1 in melanoma patients injected with mature autologous monocyte-derived dendritic cells (DCs) loaded with long NY-ESO-1-derived pe
Autor:
Kathryn, Farrand, Lauren E, Holz, Laura, Ferrer-Font, Michael D, Wilson, Mitch, Ganley, Jordan J, Minnell, Ching-Wen, Tang, Gavin F, Painter, William R, Heath, Ian F, Hermans, Olivia K, Burn
Publikováno v:
Current Protocols. 2
Full-spectrum flow cytometry is now routinely used in many laboratories internationally, and the demand for this technology is rapidly increasing. With capacity to use larger and more complex staining panels, standardized protocols are required for o
Publikováno v:
Oxford Open Immunology. 2
Lay Summary Vaccine-induced immune responses generally involve activation of immune cells called T and B cells that have a variety of mechanisms to limit the infection. Each T or B cell has a randomly generated receptor for binding pathogen-derived a
Publikováno v:
Molecular immunology. 130
The capacity of α-galactosylceramide (α-GalCer) to act as an anti-cancer agent in mice through the specific stimulation of type I NKT (iNKT) cells has prompted extensive investigation to translate this finding to the clinic. However, low frequencie
Autor:
Olivia K. Burn, Regan J. Anderson, Collin Brooks, Gavin F. Painter, Robert Weinkove, Astrid Authier-Hall, Ian F. Hermans, Andrew J. Marshall
Publikováno v:
Cancer Immunology Research. 7:B103-B103
Inhibitors of the mevalonate pathway have been found to induce inflammatory reactions and delay the progression of cancer. Emerging evidence suggests these inhibitors sensitise immune cells to signalling from the myeloid differentiation primary respo