Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Olivia J Conway"'
Autor:
Olivia J Conway, Minerva M Carrasquillo, Xue Wang, Jenny M Bredenberg, Joseph S Reddy, Samantha L Strickland, Curtis S Younkin, Jeremy D Burgess, Mariet Allen, Sarah J Lincoln, Thuy Nguyen, Kimberly G Malphrus, Alexandra I Soto, Ronald L Walton, Bradley F Boeve, Ronald C Petersen, John A Lucas, Tanis J Ferman, William P Cheshire, Jay A van Gerpen, Ryan J Uitti, Zbigniew K Wszolek, Owen A Ross, Dennis W Dickson, Neill R Graff-Radford, Nilüfer Ertekin-Taner
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-12 (2018)
Abstract Background Rare coding variants ABI3_rs616338-T and PLCG2_rs72824905-G were identified as risk or protective factors, respectively, for Alzheimer’s disease (AD). Methods We tested the association of these variants with five neurodegenerati
Externí odkaz:
https://doaj.org/article/26aae77c26cb4a6c9e381ff00070adea
Autor:
Anna Alvarez-Guaita, Satish Patel, Koini Lim, Afreen Haider, Liang Dong, Olivia J. Conway, Marcella K.L. Ma, Davide Chiarugi, Vladimir Saudek, Stephen O’Rahilly, David B. Savage
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108810- (2021)
Summary: Adipogenin (Adig) is an adipocyte-enriched transmembrane protein. Its expression is induced during adipogenesis in rodent cells, and a recent genome-wide association study associated body mass index (BMI)-adjusted leptin levels with the ADIG
Externí odkaz:
https://doaj.org/article/429f6fb808504b2db108fb2f69b10633
Autor:
Joycelyn Tan, Sam Virtue, Dougall M. Norris, Olivia J. Conway, Ming Yang, Christopher Gribben, Fatima Lugtu, Ioannis Kamzolas, James R. Krycer, Richard J. Mills, Conceição Pereira, Martin Dale, Amber S. Shun-Shion, Harry J. M. Baird, James A. Horscroft, Alice P. Sowton, Marcella Ma, Stefania Carobbio, Evangelia Petsalaki, Andrew J. Murray, David C. Gershlick, James E. Hudson, Ludovic Vallier, Kelsey H Fisher-Wellman, Christian Frezza, Antonio Vidal-Puig, Daniel J. Fazakerley
SUMMARYCell culture is generally considered to be hyperoxic. However, the importance of cellular oxygen consumption is often underappreciated, with rates of oxygen consumption often sufficient to cause hypoxia at cell monolayers. We initially focused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fe7ad781bc0666a5a17fe82ad499dc9
https://doi.org/10.1101/2022.11.29.516437
https://doi.org/10.1101/2022.11.29.516437
Autor:
Alexis Diaz-Vegas, Dougall M Norris, Sigrid Jall-Rogg, Kristen C Cooke, Olivia J Conway, Amber S Shun-Shion, Xiaowen Duan, Meg Potter, Julian van Gerwen, Harry JM Baird, Sean J Humphrey, David E James, Daniel J Fazakerley, James G Burchfield
Funder: Wellcome-MRC, Institute of Metabolic Science, Metabolic Research Laboratories, Imaging Core
Insulin-induced GLUT4 translocation to the plasma membrane in muscle and adipocytes is crucial for whole-body glucose homeostasis. Currently, GLU
Insulin-induced GLUT4 translocation to the plasma membrane in muscle and adipocytes is crucial for whole-body glucose homeostasis. Currently, GLU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8e3414c83ad8e0d21b7cc204c00eff
Autor:
John A. Lucas, Kimberly G. Malphrus, Minerva M. Carrasquillo, Joseph S. Reddy, Olivia J. Conway, Mariet Allen, Zbigniew K. Wszolek, Owen A. Ross, Christian C. Prusinski, Hélène Morel, Tanis J. Ferman, Neill R. Graff-Radford, Sarah Lincoln, Alexandra I. Soto, Ronald C. Petersen, Julia E. Crook, Dennis W. Dickson, Thuy Nguyen, Tulsi A. Patel, Ryan J. Uitti, Ronald L. Walton, Samantha L. Strickland, Bradley F. Boeve, Melissa E. Murray, Nilufer Ertekin-Taner
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-12 (2020)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Missense variants ABI3_rs616338-T and PLCG2_rs72824905-G were previously associated with elevated or reduced risk of Alzheimer’s disease (AD), respectively. Despite reports of associations with other neurodegenerative diseases, there are few studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a1afe3563714df6146653177a70556
http://link.springer.com/article/10.1186/s40478-020-01050-0
http://link.springer.com/article/10.1186/s40478-020-01050-0
Autor:
Xiaowen Duan, Dougall M. Norris, Sean J. Humphrey, Pengyi Yang, Kristen C. Cooke, Will P. Bultitude, Benjamin L. Parker, Olivia J. Conway, James G. Burchfield, James R. Krycer, Frances M. Brodsky, David E. James, Daniel J. Fazakerley
Publikováno v:
The Biochemical journal. 479(11)
Trafficking regulator of GLUT4-1, TRARG1, positively regulates insulin-stimulated GLUT4 trafficking and insulin sensitivity. However, the mechanism(s) by which this occurs remain(s) unclear. Using biochemical and mass spectrometry analyses we found t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee51528be71175bbb3b9cdc7db08c6ab
https://pubmed.ncbi.nlm.nih.gov/35594055
https://pubmed.ncbi.nlm.nih.gov/35594055
Autor:
Davide Chiarugi, Stephen O'Rahilly, Satish Patel, Liang Dong, David B. Savage, Anna Alvarez-Guaita, Vladimir Saudek, Koini Lim, Olivia J. Conway, Marcella Ma, Afreen Haider
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108810-(2021)
Cell Reports
Cell Reports
Summary Adipogenin (Adig) is an adipocyte-enriched transmembrane protein. Its expression is induced during adipogenesis in rodent cells, and a recent genome-wide association study associated body mass index (BMI)-adjusted leptin levels with the ADIG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a7aafed00da58766204188c19ada93
http://www.sciencedirect.com/science/article/pii/S2211124721001248
http://www.sciencedirect.com/science/article/pii/S2211124721001248
Autor:
Kristen C. Cooke, Daniel J. Fazakerley, Xiaowen Duan, WP Bultitude, Frances M. Brodsky, James G. Burchfield, Pengyi Yang, Olivia J. Conway, James R. Krycer, David E. James, Dougall M. Norris, Benjamin L. Parker, Sean J. Humphrey
Trafficking regulator of GLUT4-1, TRARG1, positively regulates insulin-stimulated GLUT4 trafficking and insulin sensitivity. However, the mechanism(s) by which this occurs remain(s) unclear. Using biochemical and mass spectrometry analyses we found t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaffe058507f8ea400b02c60f7517277
https://doi.org/10.1101/2020.12.07.415257
https://doi.org/10.1101/2020.12.07.415257
Autor:
Ronald C. Petersen, Ronald L. Walton, Jeremy D. Burgess, Alexandra I. Soto, Minerva M. Carrasquillo, Nilufer Ertekin-Taner, Sarah Lincoln, Dennis W. Dickson, Joseph S. Reddy, Kimberly G. Malphrus, Ryan J. Uitti, John A. Lucas, Owen A. Ross, Curtis S. Younkin, Zbigniew K. Wszolek, Thuy Nguyen, Samantha L. Strickland, Tanis J. Ferman, Bradley F. Boeve, Jay A. van Gerpen, Jenny M. Bredenberg, Neill R. Graff-Radford, Xue Wang, William P. Cheshire, Olivia J. Conway, Mariet Allen
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-12 (2018)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background Rare coding variants ABI3_rs616338-T and PLCG2_rs72824905-G were identified as risk or protective factors, respectively, for Alzheimer’s disease (AD). Methods We tested the association of these variants with five neurodegenerative diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2856a7de409685d50c6e77a9e02029
http://link.springer.com/article/10.1186/s13024-018-0289-x
http://link.springer.com/article/10.1186/s13024-018-0289-x
Autor:
Joseph S. Reddy, Maria T. Greig Custo, Sarah Lincoln, Ronald C. Petersen, Minerva M. Carrasquillo, Kimberly G. Malphrus, Curtis S. Younkin, Neill R. Graff-Radford, Thuy Nguyen, Jenny M. Bredenberg, Dennis W. Dickson, Nilufer Ertekin-Taner, Olivia J. Conway, Mariet Allen, Ranjan Duara
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74f66c00ce6928202c86be179d074995
https://doi.org/10.1016/j.jalz.2018.06.164
https://doi.org/10.1016/j.jalz.2018.06.164