Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Olivia J, Marola"'
Autor:
Cory A. Diemler, Michael MacLean, Sarah E. Heuer, Amanda A. Hewes, Olivia J. Marola, Richard T. Libby, Gareth R. Howell
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
In recent years, microglia have been highlighted for playing integral roles in neurodegenerative diseases, like glaucoma. To better understand the role of microglia during chronic ocular hypertension, we depleted microglia from aged (9–12 months ol
Externí odkaz:
https://doaj.org/article/6b27b539c39343098b06fa8d8c1711f0
Autor:
Margaret E. Maes, Ryan J. Donahue, Cassandra L. Schlamp, Olivia J. Marola, Richard T. Libby, Robert W. Nickells
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-22 (2023)
Abstract Background Pro-apoptotic BAX is a central mediator of retinal ganglion cell (RGC) death after optic nerve damage. BAX activation occurs in two stages including translocation of latent BAX to the mitochondrial outer membrane (MOM) and then pe
Externí odkaz:
https://doaj.org/article/7657e4fe09f54146a892dfbcaf469f51
Autor:
Maria A. Telpoukhovskaia, Thomas J. Murdy, Olivia J. Marola, Kevin Charland, Michael MacLean, Tain Luquez, Alexandra M. Lish, Sarah Neuner, Amy Dunn, Kristen D. Onos, Jesse Wiley, Derek Archer, Matthew J. Huentelman, Matthias Arnold, Vilas Menon, Alison Goate, Linda J. Van Eldik, Paul R. Territo, Gareth R. Howell, Gregory W. Carter, Kristen M. S. O'Connell, Catherine C. Kaczorowski, the 2022 JAX CADR Workshop
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION In September 2022, The Jackson Laboratory Center for Alzheimer's and Dementia Research (JAX CADR) hosted a workshop with leading researchers in the Alzheimer's disease and related dementias (ADRD) field. METHODS During the works
Externí odkaz:
https://doaj.org/article/cf95533f4c0f4321bd855f02582741fa
Autor:
Olivia J. Marola, Sarah E. R. Yablonski, Peter G. Shrager, Robert W. Nickells, Richard T. Libby
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/eb892c47a1154f999d3036c99161ddab
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Endothelin (EDN, also known as ET) signaling has been suggested to be an important mediator of retinal ganglion cell (RGC) death in glaucoma. Antagonism of EDN receptors (EDNRA and EDNRB, also known as ET-A and ET-B) prevented RGC death in m
Externí odkaz:
https://doaj.org/article/83fc65d8bc674c709d199ae6406aeed7
Autor:
Stephanie B. Syc-Mazurek, Hongtian Stanley Yang, Olivia J. Marola, Gareth R. Howell, Richard T. Libby
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-12 (2022)
Abstract Injury to the axons of retinal ganglion cells (RGCs) is a key pathological event in glaucomatous neurodegeneration. The transcription factors JUN (the target of the c-Jun N-terminal kinases, JNKs) and DDIT3/CHOP (a mediator of the endoplasmi
Externí odkaz:
https://doaj.org/article/02438d6908a94953b196ae00e8d3a4ee
Autor:
Olivia J, Marola, Sarah E R, Yablonski, Peter G, Shrager, Robert W, Nickells, Richard T, Libby
Publikováno v:
Cell death discovery. 8(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42f1d54f5878250b79391ac2ec7542f8
https://pubmed.ncbi.nlm.nih.gov/35869049
https://pubmed.ncbi.nlm.nih.gov/35869049
Publikováno v:
Cell Death Discovery, Vol 5, Iss 1, Pp 1-8 (2019)
Cell Death Discovery
Cell Death Discovery
Glaucoma is an age-related neurodegenerative disease characterized by the progressive loss of retinal ganglion cells (RGCs). Chronic ocular hypertension, an important risk factor for glaucoma, leads to RGC axonal injury at the optic nerve head. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19333143f40151e8f89aeadb1caf08b
http://link.springer.com/article/10.1038/s41420-019-0220-4
http://link.springer.com/article/10.1038/s41420-019-0220-4
Autor:
Stephanie B, Syc-Mazurek, Hongtian Stanley, Yang, Olivia J, Marola, Gareth R, Howell, Richard T, Libby
Publikováno v:
Cell deathdisease. 13(3)
Injury to the axons of retinal ganglion cells (RGCs) is a key pathological event in glaucomatous neurodegeneration. The transcription factors JUN (the target of the c-Jun N-terminal kinases, JNKs) and DDIT3/CHOP (a mediator of the endoplasmic reticul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7d81a6b8138153b2550cc7d73f4516d
https://pubmed.ncbi.nlm.nih.gov/35296661
https://pubmed.ncbi.nlm.nih.gov/35296661
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 9, Pp 1-13 (2020)
Cell Death and Disease, Vol 11, Iss 9, Pp 1-13 (2020)
Glaucoma is a neurodegenerative disease characterized by loss of retinal ganglion cells (RGCs), the output neurons of the retina. Multiple lines of evidence show the endothelin (EDN, also known as ET) system is important in glaucomatous neurodegenera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc10b506aa3991f889f6bb4904beac4
https://pubmed.ncbi.nlm.nih.gov/32980857
https://pubmed.ncbi.nlm.nih.gov/32980857