Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Olivia Harder"'
Autor:
Miaoge Xue, Boxuan Simen Zhao, Zijie Zhang, Mijia Lu, Olivia Harder, Phylip Chen, Zhike Lu, Anzhong Li, Yuanmei Ma, Yunsheng Xu, Xueya Liang, Jiyong Zhou, Stefan Niewiesk, Mark E. Peeples, Chuan He, Jianrong Li
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Here, Xue et al. identify N 6-methyladenosine (m6A) modification sites in RNAs of respiratory syncytial virus (RSV) and show that these sites, particularly sites in the transcript encoding for the viral glycoprotein, affect virus replication in prima
Externí odkaz:
https://doaj.org/article/ae5353928f864471a17a92fe4c1248b7
Autor:
Miaoge Xue, Yuexiu Zhang, Haitao Wang, Elizabeth L Kairis, Mijia Lu, Sadeem Ahmad, Zayed Attia, Olivia Harder, Zijie Zhang, Jiangbo Wei, Phylip Chen, Youling Gao, Mark E Peeples, Amit Sharma, Prosper Boyaka, Chuan He, Sun Hur, Stefan Niewiesk, Jianrong Li
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010142 (2021)
Human respiratory syncytial virus (RSV) is the leading cause of respiratory tract infections in humans. A well-known challenge in the development of a live attenuated RSV vaccine is that interferon (IFN)-mediated antiviral responses are strongly supp
Externí odkaz:
https://doaj.org/article/b173c27ab4264a278cb1cb7a1cbacf70
Autor:
Yuanmei Ma, Stefan Niewiesk, Kristen French-Kim, Basavaraj Binjawadagi, Kelsey A Brakel, Jianrong Li, M.R. Watts, Olivia Harder
Publikováno v:
Vaccine
Respiratory syncytial virus (RSV) is one of the most important causes of respiratory disease in infants, immunocompromised individuals, and the elderly. Natural infection does not result in long-term immunity, and there is no licensed vaccine. Vesicu
Autor:
Olivia Harder, Francesca T. Bovier, Sudipta Biswas, Tara C. Marcink, Anne Moscona, Matteo Porotto, Stefan Niewiesk, Christopher A. Alabi, Ksenia Rybkina
Publikováno v:
ACS Nano
Measles virus (MeV) infection remains a significant public health threat despite ongoing global efforts to increase vaccine coverage. As eradication of MeV stalls, and vulnerable populations expand, effective antivirals against MeV are in high demand
Autor:
Kelsey A. Brakel, Yuanmei Ma, Rashmi Binjawadagi, Olivia Harder, Mauria Watts, Jianrong Li, Basavaraj Binjawadagi, Stefan Niewiesk
Publikováno v:
Virology. 575
Respiratory syncytial virus is an important cause of pneumonia in children, the elderly, and immunocompromised individuals. The attachment (G) protein of RSV generates neutralizing antibodies in natural RSV infection which correlate with protection a
Autor:
Fabrizio Angius, Branka Horvat, Stefan Niewiesk, Anne Moscona, Marion Ferren, Olivia Harder, Jennifer Drew-Bear, Tara C. Marcink, Matteo Porotto, N. Valerio Dorrello, Camilla Predella, Cyrille Mathieu, Francesca T. Bovier, Alexander L. Greninger
Publikováno v:
Cellular and molecular immunology
Cellular and molecular immunology, 2021, 18 (7), pp.1835-1837. ⟨10.1038/s41423-021-00691-y⟩
Cellular and molecular immunology, Nature Publishing Group/Chinese Society of Immunology, 2021, 18 (7), pp.1835-1837. ⟨10.1038/s41423-021-00691-y⟩
Cell Mol Immunol
Cellular and molecular immunology, 2021, 18 (7), pp.1835-1837. ⟨10.1038/s41423-021-00691-y⟩
Cellular and molecular immunology, Nature Publishing Group/Chinese Society of Immunology, 2021, 18 (7), pp.1835-1837. ⟨10.1038/s41423-021-00691-y⟩
Cell Mol Immunol
International audience; No abstract available
Autor:
Stefan Niewiesk, Krista M. D. La Perle, Kathryn M Emmer, Anne J. Gemensky-Metzler, Dondrae J Coble, Eric J Miller, Olivia Harder, Amanda E Sparks
Publikováno v:
Comp Med
Aged cotton rats (Sigmodon hispidus) from an established breeding colony displayed signs of spontaneous exophthalmos. Of a total of 118 colony animals that were older than 6 mo of age, 37 (31%) displayed signs of exophthalmos. These rats were clinica
Autor:
Yunsheng Xu, Chuan He, Mark E. Peeples, Olivia Harder, Xueya Liang, Boxuan Simen Zhao, Jianrong Li, Zongdi Feng, Miaoge Xue, Jiyong Zhou, Mijia Lu, Thomas Z. Gao, Zijie Zhang, Stefan Niewiesk, Anzhong Li
Publikováno v:
Nature Microbiology. 5:584-598
Internal N6-methyladenosine (m6A) modification is one of the most common and abundant modifications of RNA. However, the biological roles of viral RNA m6A remain elusive. Here, using human metapneumovirus (HMPV) as a model, we demonstrate that m6A se
Autor:
Olivia Harder, Mark E. Peeples, Hong M. Moulton, Stefan Niewiesk, Sara M. Johnson, Gia Green, Kelsey A Brakel, Heather M. Costello, Antonius G. P. Oomens
Publikováno v:
J Virol
Respiratory syncytial virus (RSV) has been reported to use CX3CR1 in vitro as a receptor on cultured primary human airway epithelial cultures. To evaluate CX3CR1 as the receptor for RSV in vivo, we used the cotton rat animal model because of its high
Autor:
Shana R Burstein, Bert K. Rima, Jennifer Drew-Bear, Stefan Niewiesk, Michael Boeckh, Tara C. Marcink, Olivia Harder, Alexander L. Greninger, Michelle J. Lin, Matteo Porotto, Ksenia Rybkina, Ryan C. Shean, Negar Makhsous, Anne Moscona, Francesca T. Bovier
Publikováno v:
J Clin Invest
The capacity of respiratory viruses to undergo evolution within the respiratory tract raises the possibility of evolution under the selective pressure of the host environment or drug treatment. Long-term infections in immunocompromised hosts are pote