Immunocompetent astrocytes and microglia display major differences in the processing of the invariant chain and in the expression of active cathepsin L and cathepsin S

Autor: Sigrid Riese, Olivia Gresser, Anne Régnier-Vigouroux, Ekkehard Weber, Andrea Hellwig

Publikováno v: European Journal of Immunology. 31:1813-1824

The role of astrocytes and microglia as antigen-presenting cells in the brain is still controversial. In this study we have analyzed and compared aspects of the molecular machinery that underlies MHC class II trafficking in immunocompetent astrocytes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::713211719d7f45e517e2a55b6ec64301
https://doi.org/10.1002/1521-4141(200106)31:6<1813::aid-immu1813>3.0.co

Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function

Autor: Adrien Kissenpfennig, Yann Bordat, Isabelle Coste, Bernard Malissen, Valérie Clair-Moninot, Eric Prina, Ken Shortman, Joanne Pooley, Nikolaus Romani, Serge Lebecque, Geneviève Milon, Hella Stössel, Olivia Gresser, Sem Saeland, Edgar Badell, Nathalie Winter, Patrice Douillard, Smina Ait-Yahia, Thierry Lang, Toufic Renno

Publikováno v: Molecular and Cellular Biology
Molecular and Cellular Biology, 2005, 25 (1), pp.88-99. ⟨10.1128/MCB.25.1.88-99.2005⟩
Molecular and Cellular Biology, American Society for Microbiology, 2005, 25 (1), pp.88-99. ⟨10.1128/MCB.25.1.88-99.2005⟩
Kissenpfennig, A, Ait-Yahia, S, Clair-Moninot, V, Stossel, H, Badell, E, Bordat, Y, Pooley, J L, Lang, T, Prina, E, Coste, I, Gresser, O, Renno, T, Winter, N, Milon, G, Shortman, K, Romani, N, Lebecque, S, Malissen, B, Saeland, S & Douillard, P 2005, ' Disruption of the langerin/CD207 Gene Abolishes Birbeck Granules without a Marked Loss of Langerhans Cell Function ' Molecular and Cellular Biology, vol 25(1), no. 1, pp. 88-99 . DOI: 10.1128/MCB.25.1.88-99.2005

Langerin is a C-type lectin expressed by a subset of dendritic leukocytes, the Langerhans cells (LC). Langerin is a cell surface receptor that induces the formation of an LC-specific organelle, the Birbeck granule (BG). We generated a langerin(-/-) m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebce5d1925a69e08f21a8f03d2192eb9
https://hal.science/hal-00165762

Transient aggregation of ubiquitinated proteins during dendritic cell maturation

Autor: Fanny Cappello, Philippe Pierre, Voahirana Camosseto, Evelina Gatti, Olivia Gresser, Hugues Lelouard

Publikováno v: Nature. 417(6885)

Dendritic cells (DCs) are antigen-presenting cells with the unique capacity to initiate primary immune responses. Dendritic cells have a remarkable pattern of differentiation (maturation) that exhibits highly specific mechanisms to control antigen pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f883a800d0baa399d94b7e6842b34aa5
https://pubmed.ncbi.nlm.nih.gov/12000969