Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Olivia G Kelly"'
Autor:
Corinne Haller, Julie Piccand, Filippo De Franceschi, Yuki Ohi, Anindita Bhoumik, Christophe Boss, Umberto De Marchi, Guillaume Jacot, Sylviane Metairon, Patrick Descombes, Andreas Wiederkehr, Alessio Palini, Nicolas Bouche, Pascal Steiner, Olivia G. Kelly, Marine R.-C. Kraus
Publikováno v:
Stem Cell Reports, Vol 12, Iss 4, Pp 787-800 (2019)
Summary: In type 1 diabetes, a renewable source of human pancreatic β cells, in particular from human induced pluripotent stem cell (hiPSC) origin, would greatly benefit cell therapy. Earlier work showed that pancreatic progenitors differentiated fr
Externí odkaz:
https://doaj.org/article/3f66809f796c41b7b0c7c165f61695af
Autor:
Talitha van der Meulen, Ruiyu Xie, Olivia G Kelly, Wylie W Vale, Maike Sander, Mark O Huising
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52181 (2012)
The peptide hormone Urocortin 3 (Ucn 3) is abundantly and exclusively expressed in mouse pancreatic beta cells where it regulates insulin secretion. Here we demonstrate that Ucn 3 first appears at embryonic day (E) 17.5 and, from approximately postna
Externí odkaz:
https://doaj.org/article/77a6f552f8b94b5fa3adb2dbf44a9e5b
Autor:
Thomas C Schulz, Holly Y Young, Alan D Agulnick, M Josephine Babin, Emmanuel E Baetge, Anne G Bang, Anindita Bhoumik, Igor Cepa, Rosemary M Cesario, Carl Haakmeester, Kuniko Kadoya, Jonathan R Kelly, Justin Kerr, Laura A Martinson, Amanda B McLean, Mark A Moorman, Janice K Payne, Mike Richardson, Kelly G Ross, Eric S Sherrer, Xuehong Song, Alistair Z Wilson, Eugene P Brandon, Chad E Green, Evert J Kroon, Olivia G Kelly, Kevin A D'Amour, Allan J Robins
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37004 (2012)
Development of a human embryonic stem cell (hESC)-based therapy for type 1 diabetes will require the translation of proof-of-principle concepts into a scalable, controlled, and regulated cell manufacturing process. We have previously demonstrated tha
Externí odkaz:
https://doaj.org/article/217b85207ea64dde8656ee24573940b2
Autor:
Margaret H. Baron, Anna-Katerina Hadjantonakis, Irina V. Larina, Wei Shen, Mary E. Dickinson, Olivia G. Kelly
Publikováno v:
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology. 292:333-341
The development of the cardiovascular system is a highly dynamic process dependent on multiple signaling pathways regulating proliferation, differentiation, migration, cell-cell and cell-matrix interactions. To characterize cell and tissue dynamics d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c577e2321b65a8823c99cd111e69b9ad
https://doi.org/10.1002/ar.20821
https://doi.org/10.1002/ar.20821
Autor:
Anna-Katerina Hadjantonakis, Elizabeth A. V. Jones, Stephen Willey, Stuart T. Fraser, Olivia G. Kelly, Mary E. Dickinson, Margaret H. Baron, Kenneth E. Sahr
Publikováno v:
genesis. 42:162-171
We report the first endothelial lineage-specific transgenic mouse allowing live imaging at subcellular resolution. We generated an H2B-EYFP fusion protein which can be used for fluorescent labeling of nucleosomes and used it to specifically label end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4506bb1c42be4e9fa1cc5f172c532b1
https://doi.org/10.1002/gene.20139
https://doi.org/10.1002/gene.20139
Publikováno v:
Development. 131:2803-2815
Recent work has identified LDL receptor-related family members, Lrp5 and Lrp6, as co-receptors for the transduction of Wnt signals. Our analysis of mice carrying mutations in both Lrp5 and Lrp6 demonstrates that the functions of these genes are redun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604abca55ffd51afa8320148ce56dd89
https://doi.org/10.1242/dev.01137
https://doi.org/10.1242/dev.01137
Autor:
Olivia G. Kelly, Jane Brennan, Joel Zupicich, Lisa V. Goodrich, Kevin J. Mitchell, Philip A. Leighton, Kariena K. Dill, Xiaowei Lu, Paul Wakenight, Paul Scherz, Brian Avery, Peri Tate, Edivinia Pangilinan, Marc Tessier-Lavigne, Kathy I. Pinson, William C. Skarnes
Publikováno v:
Nature Genetics. 28:241-249
We describe the successful application of a modified gene-trap approach, the secretory trap, to systematically analyze the functions in vivo of large numbers of genes encoding secreted and membrane proteins. Secretory-trap insertions in embryonic ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d934f0ae97bd779e78483b21b7424b93
https://doi.org/10.1038/90074
https://doi.org/10.1038/90074
Autor:
Douglas A. Melton, Olivia G. Kelly
Publikováno v:
Developmental Dynamics. 218:615-627
Xenopus embryos have several experimental advantages for studying development. Although these advantages have traditionally been used to elucidate mechanisms of early development, they can also be exploited to investigate issues later in development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0dec72f1c44ae58febdfa3a01eeae1f
https://doi.org/10.1002/1097-0177(2000)9999:9999<::aid-dvdy1027>3.0.co
https://doi.org/10.1002/1097-0177(2000)9999:9999<::aid-dvdy1027>3.0.co
Autor:
Douglas A. Melton, Olivia G. Kelly
Publikováno v:
Trends in Genetics. 11:273-278
The formation of the vertebrate central nervous system depends on a series of inductive interactions. Ventral ectoderm gives rise to epidermis (skin), whereas dorsal ectoderm forms neurectoderm, which is regionalized along the anteroposterior axis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97878ae43cf83c72c4170e39bf4933b
https://doi.org/10.1016/s0168-9525(00)89074-5
https://doi.org/10.1016/s0168-9525(00)89074-5
Autor:
William C. Skarnes, Kazuyuki Sugahara, Momoyo Ueno, Marta Busse, Marion Kusche-Gullberg, Olivia G. Kelly, Shuhei Yamada
Publikováno v:
The Journal of biological chemistry. 279(31)
Mutational defects in either EXT1 or EXT2 genes cause multiple exostoses, an autosomal hereditary human disorder. The EXT1 and EXT2 genes encode glycosyltransferases that play an essential role in heparan sulfate chain elongation. In this study, we h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d18e45d4a7699f4749b765b85fb83054
https://pubmed.ncbi.nlm.nih.gov/15161920
https://pubmed.ncbi.nlm.nih.gov/15161920