Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Olivia D. Cooney"'
Autor:
Man K.S. Lee, Olivia D. Cooney, Xuzhu Lin, Shaktypreya Nadarajah, Dragana Dragoljevic, Kevin Huynh, Danise-Ann Onda, Sandra Galic, Peter J. Meikle, Thomas Edlund, Morgan D. Fullerton, Bruce E. Kemp, Andrew J. Murphy, Kim Loh
Publikováno v:
Molecular Metabolism, Vol 61, Iss , Pp 101514- (2022)
Objectives: Dysregulation of cholesterol metabolism in the liver and hematopoietic stem and progenitor cells (HSPCs) promotes atherosclerosis development. Previously, it has been shown that HMG-CoA-Reductase (HMGCR), the rate-limiting enzyme in the m
Externí odkaz:
https://doaj.org/article/8e3ca735c9ca4ee3934879d9b15a6a5b
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
Over the past decade, the use of probiotics to modify the gut microbiome has become a public spotlight in reducing the severity of a number of chronic diseases such as autoimmune disease, diabetes, cancer and cardiovascular disease. Recently, the gut
Externí odkaz:
https://doaj.org/article/c0eadd7d04d846a583942fc14d364690
Autor:
Man K. S. Lee, Annas Al-Sharea, Waled A. Shihata, Camilla Bertuzzo Veiga, Olivia D. Cooney, Andrew J. Fleetwood, Michelle C. Flynn, Ellen Claeson, Clovis S. Palmer, Graeme I. Lancaster, Darren C. Henstridge, John A. Hamilton, Andrew J. Murphy
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Monocytes in humans consist of 3 subsets; CD14+CD16− (classical), CD14+CD16+ (intermediate) and CD14dimCD16+ (non-classical), which exhibit distinct and heterogeneous responses to activation. During acute inflammation CD14+CD16− monocytes are sig
Externí odkaz:
https://doaj.org/article/877fdbb79e87480fa17aaf1845695887
Autor:
Annas Al-Sharea, Man K. S. Lee, Alexandra Whillas, Danielle L. Michell, Waled A. Shihata, Alyce J. Nicholls, Olivia D. Cooney, Michael J. Kraakman, Camilla Bertuzzo Veiga, Ann-Maree Jefferis, Kristy Jackson, Prabhakara R. Nagareddy, Gavin Lambert, Connie H. Y. Wong, Karen L. Andrews, Geoff A. Head, Jaye Chin-Dusting, Andrew J. Murphy
Publikováno v:
Haematologica, Vol 104, Iss 3 (2019)
Hypertension is a major, independent risk factor for atherosclerotic cardiovascular disease. However, this pathology can arise through multiple pathways, which could influence vascular disease through distinct mechanisms. An overactive sympathetic ne
Externí odkaz:
https://doaj.org/article/4e2a37be40d14ab48b844e3e3f467be4
Autor:
Man K.S. Lee, Emma C. Josefsson, Elizabeth Morriss, Nordin M J Hanssen, Michelle C Flynn, Camilla Bertuzzo-Veiga, Dragana Dragoljevic, Olivia D. Cooney, Andrew J. Murphy, Fatima Baig, Gopalkrishna Sreejit, Benjamin T. Kile, Annas Al-Sharea, Michael J Kraakman, Prabhakara R Nagareddy, Mark E. Cooper
Publikováno v:
Arteriosclerosis Thrombosis and Vascular Biology, 41(3), 1167-1178. LIPPINCOTT WILLIAMS & WILKINS
Arterioscler Thromb Vasc Biol
Arteriosclerosis, thrombosis, and vascular biology, 41(3), 1167-1178. Lippincott Williams and Wilkins
Arterioscler Thromb Vasc Biol
Arteriosclerosis, thrombosis, and vascular biology, 41(3), 1167-1178. Lippincott Williams and Wilkins
Objective: People with diabetes are at a significantly higher risk of cardiovascular disease, in part, due to accelerated atherosclerosis. Diabetic subjects have increased number of platelets that are activated, more reactive, and respond suboptimall
Autor:
Alyce J. Nicholls, Man K.S. Lee, Michael J Kraakman, Andrew J. Murphy, Kristy L. Jackson, Prabhakara R Nagareddy, Jaye Chin-Dusting, Annas Al-Sharea, Ann Maree Jefferis, Olivia D. Cooney, Geoff Head, Danielle L. Michell, Alexandra Whillas, Connie H.Y. Wong, Karen L. Andrews, Gavin W. Lambert, Waled A. Shihata, Camilla Bertuzzo Veiga
Publikováno v:
Haematologica
Hypertension is a major, independent risk factor for atherosclerotic cardiovascular disease. However, this pathology can arise through multiple pathways, which could influence vascular disease through distinct mechanisms. An overactive sympathetic ne
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
Frontiers in Endocrinology
Frontiers in Endocrinology
Over the past decade, the use of probiotics to modify the gut microbiome has become a public spotlight in reducing the severity of a number of chronic diseases such as autoimmune disease, diabetes, cancer and cardiovascular disease. Recently, the gut
Autor:
Darren C. Henstridge, Man K.S. Lee, Andrew J. Murphy, Annas Al-Sharea, Clovis S. Palmer, Michelle C Flynn, Ellen Claeson, Olivia D. Cooney, Andrew J. Fleetwood, John A. Hamilton, Graeme I. Lancaster, Waled A. Shihata, Camilla Bertuzzo Veiga
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
Monocytes in humans consist of 3 subsets; CD14+CD16− (classical), CD14+CD16+ (intermediate) and CD14dimCD16+ (non-classical), which exhibit distinct and heterogeneous responses to activation. During acute inflammation CD14+CD16− monocytes are sig
Autor:
Andrew J. Murphy, Alexandra Whillas, Man K.S. Lee, Olivia D. Cooney, Annas Al-Sharea, Dragana Dragoljevic, John A. Hamilton, Michelle C Flynn
Publikováno v:
Experimental Hematology. 76:S48
Rheumatoid arthritis (RA) patients have an increased risk for cardiovascular disease (CVD), independent of traditional risk factors such as plasma cholesterol levels. Interestingly, RA patients have elevated activity of the sympathetic nervous system
Autor:
Annas Al-Sharea, Olivia D. Cooney, Michelle C Flynn, Graeme I. Lancaster, Gerard Pernes, Man Lee, Andrew J. Murphy
Publikováno v:
Experimental Hematology. 76:S45
A high salt diet (HSD) is a key risk factor for atherosclerotic-cardiovascular disease (CVD). We show that a HSD (3.6% NaCl) promotes the maturation of pathogenic TH17 cells in the bone marrow (BM) and promotes the breakdown of the BM niche, by reduc