Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Olivia A. Perng"'
Autor:
Cristina Cozzo Picca, Olivia A. Perng, Elizabeth Kropf, Jan Erikson, Christina Mergenthaler, Malinda Aitken, Andrew J. Caton, Donald M. Simons, Soyoung Oh
Publikováno v:
Proceedings of the National Academy of Sciences. 108:14890-14895
CD4 + CD25 + Foxp3 + regulatory T (Treg) cells are generated during thymocyte development and play a crucial role in preventing the immune system from attacking the body's cells and tissues. However, how the formation of these cells is directed by T-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2dc82177562fd14ebc1baf929af07d
https://doi.org/10.1073/pnas.1103810108
https://doi.org/10.1073/pnas.1103810108
Autor:
Soyoung Oh, Cristina Cozzo Picca, Andrew J. Caton, Jan Erikson, Donald M. Simons, Malinda Aitken, Olivia A. Perng
Publikováno v:
Journal of Leukocyte Biology. 88:1099-1107
Review discusses studies analyzing how the immune system generates Treg cells that can recognize self-peptides and prevent harmful autoimmune responses. The cataclysmic disease that develops in mice and humans lacking CD4+ T cells expressing the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8242a2e54655396fa17a1b4bbbc0c9f
https://doi.org/10.1189/jlb.0310183
https://doi.org/10.1189/jlb.0310183
Autor:
Yui-Hsi Wang, Xiao Feng Qin, Eiji Esashi, Yong-Jun Liu, Stephanie S. Watowich, Olivia A. Perng
Publikováno v:
Immunity. 28(4):509-520
Summary The development of distinct dendritic cell (DC) subsets is regulated by cytokines. The ligand for the FMS-like tyrosine kinase 3 receptor (Flt3L) is necessary for plasmacytoid DC (pDC) and conventional DC (cDC) maturation. The cytokine GM-CSF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82bd6fcaf4556f38432c8399bebb299e
Autor:
F. Xiao-Feng Qin, Josh Gregorio, Yong-Jun Liu, Tomoki Ito, Michel Gilliet, Yui-Hsi Wang, Maria Yang, Olivia A. Perng, Roberto Lande
Publikováno v:
The Journal of Experimental Medicine
Although there is evidence for distinct roles of myeloid dendritic cells (DCs [mDCs]) and plasmacytoid pre-DCs (pDCs) in regulating T cell–mediated adaptive immunity, the concept of functional DC subsets has been questioned because of the lack of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7f5563354150d40e356b617574c40d
https://doi.org/10.1084/jem.20061660
https://doi.org/10.1084/jem.20061660
Autor:
Malinda Aitken, Andrew L. Rankin, David S. Garlick, Andrew J. Caton, Victoria Garcia, Jan Erikson, Elizabeth Kropf, Olivia A. Perng
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 192(7)
Although therapies targeting distinct cellular pathways (e.g., anticytokine versus anti–B cell therapy) have been found to be an effective strategy for at least some patients with inflammatory arthritis, the mechanisms that determine which pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35329ddd2d8c8b051b1b00cc190d5e0
https://pubmed.ncbi.nlm.nih.gov/24591372
https://pubmed.ncbi.nlm.nih.gov/24591372
Autor:
Amrita O. Batheja, Jan Erikson, Antonio J. Pagán, Andrew J. Caton, Michele H. Metzgar, Simone Willms, Olivia A. Perng, Brian D. Hondowicz
Publikováno v:
European journal of immunology. 39(9)
T-cell recognition of peptide/MHC complexes is flexible and can lead to differential activation, but how interactions with agonist (full activation) or partial agonist (suboptimal activation) peptides can shape immune responses in vivo is not well ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6f957124cb89cf003dda7232cb067e
https://pubmed.ncbi.nlm.nih.gov/19662636
https://pubmed.ncbi.nlm.nih.gov/19662636
Recent studies have highlighted the importance of peripheral induction of Foxp3-expressing regulatory T cells (Tregs) in the dominant control of immunological tolerance. However, Foxp3 + Treg differentiation from naïve CD4 + T cells occurs only unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c385c1ce5a76622a4788cd48bd127fbf
https://europepmc.org/articles/PMC2084315/
https://europepmc.org/articles/PMC2084315/
Autor:
Michel Gilliet, Yui-Hsi Wang, Yong-Jun Liu, Omar Duramad, Olivia A. Perng, Shino Hanabuchi, F. Xiao-Feng Qin, Tomoki Ito
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 103(35)
IL-10-producing CD4 + type 1 regulatory T (Tr1) cells play a critical role in the maintenance of peripheral tolerance. Although immunosuppressive drugs, cytokines, costimulatory molecules, and immature dendritic cells are implicated in the induction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6db0a63cd5bfcff1f8c8914bb9b0a4f
https://pubmed.ncbi.nlm.nih.gov/16924108
https://pubmed.ncbi.nlm.nih.gov/16924108