Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Olivia A, Moody"'
Autor:
Kathleen F. Vincent, Edlyn R. Zhang, Angel J. Cho, Risako Kato-Miyabe, Olivia G. Mallari, Olivia A. Moody, David P. Obert, Gwi H. Park, Ken Solt
Publikováno v:
Brain Stimulation, Vol 17, Iss 3, Pp 687-697 (2024)
Background: Dopaminergic neurons in the ventral tegmental area (VTA) are crucially involved in regulating arousal, making them a potential target for reversing general anesthesia. Electrical deep brain stimulation (DBS) of the VTA restores consciousn
Externí odkaz:
https://doaj.org/article/c7d5d203874e44ac866209a40c8e77d0
Publikováno v:
Frontiers in Systems Neuroscience, Vol 15 (2021)
As the number of individuals undergoing general anesthesia rises globally, it becomes increasingly important to understand how consciousness and cognition are restored after anesthesia. In rodents, levels of consciousness are traditionally captured b
Externí odkaz:
https://doaj.org/article/2b8f6a32d3f744d29dafd5dab8d3c81d
Autor:
Risako Kato, Edlyn R. Zhang, Olivia G. Mallari, Olivia A. Moody, Kathleen F. Vincent, Eric D. Melonakos, Morgan J. Siegmann, Christa J. Nehs, Timothy T. Houle, Oluwaseun Akeju, Ken Solt
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
D-amphetamine induces emergence from sevoflurane and propofol anesthesia in rats. Dexmedetomidine is an α2-adrenoreceptor agonist that is commonly used for procedural sedation, whereas ketamine is an anesthetic that acts primarily by inhibiting NMDA
Externí odkaz:
https://doaj.org/article/17effccbefa84037a6a4ab70d698e40c
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
In the United States, fentanyl causes approximately 60,000 drug overdose deaths each year. Fentanyl is also frequently administered as an analgesic in the perioperative setting, where respiratory depression remains a common clinical problem. Naloxone
Externí odkaz:
https://doaj.org/article/5425dd6602f94b2a9095bf247565792b
Autor:
Alexandra Ross, Manali Rupji, Laura Kallay, Xin Wang, Taukir Ahmed, Yanxin Pei, Soma Sengupta, Havva Keskin, Jeanne Kowalski, James M. Cook, Andrew Jenkins, Olivia A. Moody, Maxwell Xu, Farjana Rashid, Guanguan Li, Michael D. Taylor, T. Austin Nuckols, Daniel Pomeranz Krummel, Kirsten A. Cottrill, Deborah E. Martinson, Michael Rajesh Stephen, Frank Tranghese
Publikováno v:
Journal of Neuro-Oncology. 142:411-422
Pediatric brain cancer medulloblastoma (MB) standard-of-care results in numerous comorbidities. MB is comprised of distinct molecular subgroups. Group 3 molecular subgroup patients have the highest relapse rates and after standard-of-care have a 20%
Autor:
Christa J Nehs, Edlyn R. Zhang, Ken Solt, Olivia A. Moody, Risako Kato, Kathleen Vincent, Eric D. Melonakos
Publikováno v:
Anesth Analg
General anesthesia is characterized by loss of consciousness, amnesia, analgesia, and immobility. Important molecular targets of general anesthetics have been identified, but the neural circuits underlying the discrete endpoints of general anesthesia
Publikováno v:
BJA: British Journal of Anaesthesia
Background We recently showed that a neurosteroid analogue, (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile (3β-OH), induced hypnosis in rats. The aim of the present study was to evaluate the hypnotic and anaesthetic potential of 3β-OH further u
Publikováno v:
Anesthesiology
The neural circuits underlying the distinct endpoints that define general anesthesia remain incompletely understood. It is becoming increasingly evident, however, that distinct pathways in the brain that mediate arousal and pain are involved in vario
De novo variants in GABRA2 and GABRA5 alter receptor function and contribute to early-onset epilepsy
Autor:
Olivia A. Moody, Andrew Jenkins, John J. Alexander, Elisabeth Schuler, Jason Coryell, Kameryn M. Butler, Andrew Escayg
Publikováno v:
Brain. 141:2392-2405
GABA(A) receptors are ligand-gated anion channels that are important regulators of neuronal inhibition. Mutations in several genes encoding receptor subunits have been identified in patients with various types of epilepsy, ranging from mild febrile s
Autor:
Sahil Talwar, Paul S. García, Andrew Jenkins, Amanda A. H. Freeman, Prabhjyot Saini, Donald L. Bliwise, Meagan A. Jenkins, Lynn Marie Trotti, Neil Feldman, David B. Rye, Olivia A. Moody, Brad Cherson, Joseph W. Lynch, Eric M. Hernandez
Publikováno v:
Annals of Neurology. 81:904-907