Genome-wide Methyl-Seq analysis of blood-brain targets of glucocorticoid exposure

Autor: Fayaz Seifuddin, Gary Wand, Olivia Cox, Mehdi Pirooznia, Laura Moody, Xiaoju Yang, Jonathan Tai, Gretha Boersma, Kellie Tamashiro, Peter Zandi, Richard Lee

Publikováno v: Epigenetics, Vol 12, Iss 8, Pp 637-652 (2017)

Chronic exposure to glucocorticoids (GCs) can lead to psychiatric complications through epigenetic mechanisms such as DNA methylation (DNAm). We sought to determine whether epigenetic changes in a peripheral tissue can serve as a surrogate for those

Externí odkaz: https://doaj.org/article/a11c189eacb548589acbbf7149ccf216

Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner

Autor: Katherine B. Chiappinelli, Stephen B. Baylin, Ting Wang, Reiner Strick, Pamela L. Strissel, Xiaoyun Xing, Michael J. Topper, Olivia Cox, Erin E. Grundy, Angela Yu, Stephanie Gomez, Uzma Rentia, Tomas Kanholm, Melissa Hadley, Elisa Arthofer, Noor Diab, James I. McDonald

Epithelial ovarian carcinomas are particularly deadly due to intratumoral heterogeneity, resistance to standard-of-care therapies, and poor response to alternative treatments such as immunotherapy. Targeting the ovarian carcinoma epigenome with DNA m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d898d23e497f1395dbbac63ffe031166
https://doi.org/10.1158/0008-5472.c.6513453.v1

Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner

Autor: Katherine B. Chiappinelli, Stephen B. Baylin, Ting Wang, Reiner Strick, Pamela L. Strissel, Xiaoyun Xing, Michael J. Topper, Olivia Cox, Erin E. Grundy, Angela Yu, Stephanie Gomez, Uzma Rentia, Tomas Kanholm, Melissa Hadley, Elisa Arthofer, Noor Diab, James I. McDonald

Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b6cac7a09216980d7200774c50a439
https://doi.org/10.1158/0008-5472.22429788.v1

Abstract 6020: The role of TP53 mutation status in the response to DNA methyltransferase inhibitor treatment

Autor: Khadra K. Omar, Erin E. Grundy, Olivia Cox, Melissa Hadley, Katherine B. Chiappinelli

Publikováno v: Cancer Research. 83:6020-6020

The purpose of this study was to understand the effect of p53 mutation status in ovarian cancer cells on the expression of repetitive elements (REs) following epigenetic treatment. High-grade serous ovarian carcinoma is the most aggressive subtype of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a493e3d8c0af087ddf826f04ff07319
https://doi.org/10.1158/1538-7445.am2023-6020

'My life during the lockdown': emotional experiences of european adolescents during the COVID-19 crisis

Autor: Alberto Forte, Daniela Liberato, Elena Monducci, Isabel Nöthen-Garunja, Maria Vulcan, Claudia Battaglia, Lauro Quadrana, Olivia Cox, Asja Brusić, Sara Fabbri, Paola Venturini, Martina Brandizzi, Massimiliano Orri, Cecilia Iannaco

Publikováno v: International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, MDPI, 2021, 18 (14), ⟨10.3390/ijerph18147638⟩
Volume 18
Issue 14
International Journal of Environmental Research and Public Health, Vol 18, Iss 7638, p 7638 (2021)

This study investigates, using an online self-report questionnaire, adolescents’ emotional reactions during the lockdown in a sample of 2105 secondary school students (aged 14–19) in Italy, Romania, and Croatia. We used a self-reported online que

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6af92468c06c79484582eb19a96de8
https://hdl.handle.net/11573/1662409