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Akademický článek

Genome-wide Methyl-Seq analysis of blood-brain targets of glucocorticoid exposure

Autor: Fayaz Seifuddin, Gary Wand, Olivia Cox, Mehdi Pirooznia, Laura Moody, Xiaoju Yang, Jonathan Tai, Gretha Boersma, Kellie Tamashiro, Peter Zandi, Richard Lee

Publikováno v: Epigenetics, Vol 12, Iss 8, Pp 637-652 (2017)

Chronic exposure to glucocorticoids (GCs) can lead to psychiatric complications through epigenetic mechanisms such as DNA methylation (DNAm). We sought to determine whether epigenetic changes in a peripheral tissue can serve as a surrogate for those

Externí odkaz: https://doaj.org/article/a11c189eacb548589acbbf7149ccf216

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Supplementary Table from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner

Autor: Katherine B. Chiappinelli, Stephen B. Baylin, Ting Wang, Reiner Strick, Pamela L. Strissel, Xiaoyun Xing, Michael J. Topper, Olivia Cox, Erin E. Grundy, Angela Yu, Stephanie Gomez, Uzma Rentia, Tomas Kanholm, Melissa Hadley, Elisa Arthofer, Noor Diab, James I. McDonald

Supplementary Table from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818ab8fad5d90b63257bf5c83608134d
https://doi.org/10.1158/0008-5472.22429779

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Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner

Epithelial ovarian carcinomas are particularly deadly due to intratumoral heterogeneity, resistance to standard-of-care therapies, and poor response to alternative treatments such as immunotherapy. Targeting the ovarian carcinoma epigenome with DNA m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d898d23e497f1395dbbac63ffe031166
https://doi.org/10.1158/0008-5472.c.6513453.v1

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Supplementary Figure from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner

Supplementary Figure from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e34a195a2aed3778aaabda60767c09
https://doi.org/10.1158/0008-5472.22429785.v1

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Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner

Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b6cac7a09216980d7200774c50a439
https://doi.org/10.1158/0008-5472.22429788.v1

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Abstract 6020: The role of TP53 mutation status in the response to DNA methyltransferase inhibitor treatment

Autor: Khadra K. Omar, Erin E. Grundy, Olivia Cox, Melissa Hadley, Katherine B. Chiappinelli

Publikováno v: Cancer Research. 83:6020-6020

The purpose of this study was to understand the effect of p53 mutation status in ovarian cancer cells on the expression of repetitive elements (REs) following epigenetic treatment. High-grade serous ovarian carcinoma is the most aggressive subtype of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a493e3d8c0af087ddf826f04ff07319
https://doi.org/10.1158/1538-7445.am2023-6020

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Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner

Autor: Tomas Kanholm, Melissa Hadley, Reiner Strick, Erin E. Grundy, Ting Wang, Pamela L. Strissel, Stephanie Gomez, Angela Yu, Uzma Rentia, Noor Diab, Michael J. Topper, Stephen B. Baylin, James I. McDonald, Xiaoyun Xing, Katherine B. Chiappinelli, Olivia Cox, Elisa Arthofer

Publikováno v: Cancer Research. 81:5176-5189

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff92c7a02b46f22144ea83787cf5a312
https://doi.org/10.1158/0008-5472.can-20-4243

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Characterization of glucocorticoid-induced loss of DNA methylation of the stress-response gene Fkbp5 in neuronal cells

Autor: Ha Young Song, Henri M. Garrison-Desany, Jenny L. Carey, Julia Menzies, Olivia Cox, Nuriya Gadiwalla, Richard S. Lee

Publikováno v: Epigenetics

Exposure to stress or glucocorticoids (GCs) is associated with epigenetic and transcriptional changes in genes that either mediate or are targets of GC signalling. FKBP5 (FK506 binding protein 5) is one such gene that also plays a central role in neg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ffc8dc12f1dcc3a4aa15665ad3f714
https://europepmc.org/articles/PMC8813076/

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'My life during the lockdown': emotional experiences of european adolescents during the COVID-19 crisis

Autor: Alberto Forte, Daniela Liberato, Elena Monducci, Isabel Nöthen-Garunja, Maria Vulcan, Claudia Battaglia, Lauro Quadrana, Olivia Cox, Asja Brusić, Sara Fabbri, Paola Venturini, Martina Brandizzi, Massimiliano Orri, Cecilia Iannaco

Publikováno v: International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, MDPI, 2021, 18 (14), ⟨10.3390/ijerph18147638⟩
Volume 18
Issue 14
International Journal of Environmental Research and Public Health, Vol 18, Iss 7638, p 7638 (2021)

This study investigates, using an online self-report questionnaire, adolescents’ emotional reactions during the lockdown in a sample of 2105 secondary school students (aged 14–19) in Italy, Romania, and Croatia. We used a self-reported online que

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6af92468c06c79484582eb19a96de8
https://hdl.handle.net/11573/1662409

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