Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Oliver Zschenker"'
Autor:
Oliver Zschenker, Nikola Jung, Julia Rethmeier, Sabine Trautwein, Stefanie Hertel, Marsha Zeigler, Detlev Ameis
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 7, Pp 1033-1040 (2001)
Wolman disease results from an inherited deficiency of lysosomal acid lipase (LAL; EC 3.1.1.13). This enzyme is essential for the hydrolysis of cholesteryl esters and triacylglycerols derived from endocytosed lipoproteins. Because of a complete absen
Externí odkaz:
https://doaj.org/article/da29f3d16d5f4ea6bde4a5a499b7377e
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34279 (2012)
Cell morphology determines cell behavior, signal transduction, protein-protein interaction, and responsiveness to external stimuli. In cancer, these functions profoundly contribute to resistance mechanisms to radio- and chemotherapy. With regard to t
Externí odkaz:
https://doaj.org/article/5d296280c61f4acbba3ab735ac4e92e9
Autor:
Annette Raabe, Andreas Ziegler, Oliver Zschenker, Ekkehard Dikomey, Dirk Rades, Inga Kathleen Boeckelmann, Ulrike Hoeller, Stefan Wellek, Silke Szymczak, Sonko Borstelmann, Kerstin Borgmann
Publikováno v:
Radiotherapy and Oncology. 97:26-32
Purpose To examine the association of polymorphisms in ATM (codon 158), GSTP1 (codon 105), SOD2 (codon 16), TGFB1 (position -509), XPD (codon 751), and XRCC1 (codon 399) with fibrosis and also individual radiosensitivity. Methods and materials Retros
Autor:
Géraldine Pottier, Marine Granger-Locatelli, Oliver Zschenker, Laure Sabatier, Gloria E. Reynolds, John P. Murnane, Avanti Kulkarni, Douglas Miller
Publikováno v:
DNA Repair. 8:886-900
We previously reported that a single DNA double-strand break (DSB) near a telomere in mouse embryonic stem cells can result in chromosome instability. We have observed this same type of instability as a result of spontaneous telomere loss in human tu
Autor:
Kerstin Borgmann, Agnieszka Wrona, Ingo Meier, Ekkehard Dikomey, Oliver Zschenker, Thomas Streichert
Publikováno v:
Radiotherapy and Oncology. 80:236-249
Background and purpose The genetic profile as determined by microarray is considered to be an ideal marker of the individual radiosensitivity. However, it is still an open question, whether this profile has to be determined prior to or only after irr
Publikováno v:
The Journal of Biochemistry. 140:23-38
Atherosclerosis is one of the major causes of morbidity and mortality in the western world. The existing data of elevated expression levels of proteins like DNA damage and DNA repair enzymes in human atherosclerotic plaques are reviewed. From the lit
Autor:
Lukas J.A. Stalpers, Dirk Rades, Winfried Alberti, Maarten C.C.M. Hulshof, Caro C.E. Koning, Oliver Zschenker
Publikováno v:
Radiotherapy and oncology, 75(1), 70-73. Elsevier Ireland Ltd
Toxicity and functional. outcome were evaluated in 199 MSCC-patients irradiated with 1 X 8 Gy. Motor function improved in 54/199 patients (27%). Patients who regained walking ability were 20/78 (26%). Long-term-survivors (>= 12 months) who needed re-
Publikováno v:
Journal of Biochemistry. 137:387-394
Lysosomal acid lipase (LAL; EC 3.1.1.13) is a key enzyme in the intracellular lipid metabolism. It hydrolyzes exogenous triglycerides and cholesterol esters taken up by various cell types. LAL has six potential N-glycosylation sites and one potential
Autor:
John P. Murnane, Oliver Zschenker
Publikováno v:
Deutsche Zeitschrift für Onkologie. 40:20-22
In general, cancer cells have shorter telomeres than normal somatic cells. However, compared to normal cells, they use reactivation of telomerase or other mechanisms to maintain telomere length and in consequence to bypass cell death. New results ind
Autor:
Oliver Zschenker
Publikováno v:
Deutsche Zeitschrift für Onkologie. 38:4-6