Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Oliver Weth"'
Autor:
Xuesong Li, Oliver Weth, Martin Haimann, Max F. Möscheid, Theresa S. Huber, Christoph G. Grevelding
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Schistosomes are parasitic flatworms that cause schistosomiasis, a neglected tropical disease of worldwide importance. Since standard treatment of schistosomiasis relies on a single drug, praziquantel, alternative drugs are needed. G protein
Externí odkaz:
https://doaj.org/article/e3ef3602c3494102b4fac54d05c887ac
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionSchistosomes are the only mammalian flatworms that have evolved separate sexes. A key question of schistosome research is the male-dependent sexual maturation of the female since a constant pairing contact with a male is required for the
Externí odkaz:
https://doaj.org/article/d50e48a7ff04402d9e6fd6a89458fb26
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Schistosomes are the only platyhelminths that have evolved separate sexes, and they exhibit a unique reproductive biology because the female’s sexual maturation depends on a constant pairing contact with the male. In the female, pairing leads to go
Externí odkaz:
https://doaj.org/article/2ee98e3760e340739d6969802a3e03f6
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10119 (2010)
The conserved 11 zinc-finger protein CTCF is involved in several transcriptional mechanisms, including insulation and enhancer blocking. We had previously identified two composite elements consisting of a CTCF and a TR binding site at the chicken lys
Externí odkaz:
https://doaj.org/article/2bd0c06d2f2f40729ce9c1fac0521ae4
Choice of binding sites for CTCFL compared to CTCF is driven by chromatin and by sequence preference
Autor:
Philipp Bergmaier, Marco Mernberger, Thomas Boettger, Rainer Renkawitz, Niels Galjart, Oliver Weth, Marek Bartkuhn, Sven Dienstbach
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 46(14), 7097-7107. Oxford University Press
Nucleic Acids Research, 46(14), 7097-7107. Oxford University Press
The two paralogous zinc finger factors CTCF and CTCFL differ in expression such that CTCF is ubiquitously expressed, whereas CTCFL is found during spermatogenesis and in some cancer types in addition to other cell types. Both factors share the highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f5984980aab485f24504eff7864e4a
https://doi.org/10.1093/nar/gky483
https://doi.org/10.1093/nar/gky483
Publikováno v:
Parasitology
Schistosomiasis is an acute and chronic disease caused by parasitic worms of the genus Schistosoma. Treatment is solely dependent on praziquantel. In the face of the worldwide dimension, projects have been initiated to develop new chemotherapies. Due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40ee649709a4e1163ce15d6e292c9832
https://pubmed.ncbi.nlm.nih.gov/31840628
https://pubmed.ncbi.nlm.nih.gov/31840628
Autor:
Rainer Renkawitz, Oliver Weth
Publikováno v:
Biochemistry and Cell Biology. 89:459-468
The zinc-finger protein CTCF was originally identified in the context of gene silencing and gene repression (Baniahmad et al. 1990; Lobanenkov et al. 1990). CTCF was later shown to be involved in several transcriptional mechanisms such as gene activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5472c63b20c53995f5d880ba11d145ea
https://doi.org/10.1139/o11-033
https://doi.org/10.1139/o11-033
Autor:
Katharina Günther, Rainer Renkawitz, Niels Galjart, Christine Paprotka, Manuel Baierl, Oliver Weth, Joerg Leers, Astrid Schulte
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 42(19), 11941-11951. Oxford University Press
Nucleic Acids Research, 42(19), 11941-11951. Oxford University Press
textabstractInsulators functionally separate active chromatin domains frominactive ones. The insulator factor, CTCF, has been found to bind to boundaries and to mediate insulator function. CTCF binding sites are depleted for the histone modification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff54e71e986b4de973e72610f41527eb
https://pubmed.ncbi.nlm.nih.gov/25294833
https://pubmed.ncbi.nlm.nih.gov/25294833
Autor:
Rainer Renkawitz, Yogesh S. Shouche, Katharina Günther, Oliver Weth, Marek Bartkuhn, Ramesh R. Bhonde, Sajad H. Ahanger
Publikováno v:
Scientific Reports
Insulator mediated alteration in higher-order chromatin and/or nucleosome organization is an important aspect of epigenetic gene regulation. Recent studies have suggested a key role for CP190 in such processes. In this study, we analysed the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf9409fd4164821ad23a967211150d4
https://doi.org/10.1038/srep03917
https://doi.org/10.1038/srep03917
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 4, p e10119 (2010)
PLoS ONE, Vol 5, Iss 4, p e10119 (2010)
The conserved 11 zinc-finger protein CTCF is involved in several transcriptional mechanisms, including insulation and enhancer blocking. We had previously identified two composite elements consisting of a CTCF and a TR binding site at the chicken lys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8325315e418453e2745e8f668c96bd
https://pubmed.ncbi.nlm.nih.gov/20404925
https://pubmed.ncbi.nlm.nih.gov/20404925