Integration of the catalytic subunit activates deneddylase activityin vivoas final step in fungal COP9 signalosome assembly

Autor: Martin Christmann, Gerhard H. Braus, Elena A. Beckmann, Cindy Meister, Oliver W. Draht, Oliver Valerius, Nikolas Rakebrandt, Anna M. Köhler

Publikováno v: Molecular Microbiology. 97:110-124

Summary The eight-subunit COP9 signalosome (CSN) is conserved from filamentous fungi to humans and functions at the interface between cellular signalling and protein half-life control. CSN consists of six PCI and two MPN domain proteins and forms a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63307c5ad64864ef58168bed93807722
https://doi.org/10.1111/mmi.13017

Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae

Autor: Toshitaka Kumagai, Kay Vienken, Li-Jun Ma, Toshihiro Tanaka, Christina C. Spevak, Paul S. Dyer, Mark L. Farman, Jerzy Jurka, David B. Archer, Claudio Scazzocchio, Christiane Bouchier, Miguel A. Peñalva, Gerhard H. Braus, John H. Doonan, Arnab Pain, Kiyoshi Asai, Eric U. Selker, Reinhard Fischer, James E. Galagan, Seth Purcell, William C. Nierman, Oliver W. Draht, Michelle Momany, Jennifer R. Wortman, Deborah Bell-Pedersen, Bruce W. Birren, Berl R. Oakley, Christina A. Cuomo, David W. Denning, Michael J. Hynes, Jonathan Butler, Su-In Lee, John Clutterbuck, Jae-Hyuk Yu, Christophe d'Enfert, Vladimir V. Kapitonov, Steve Harris, Gustavo H. Goldman, Masayuki Machida, Serafim Batzoglou, Sarah E. Calvo, Mathieu Paoletti, Bruce L. Miller, Matthew S. Sachs, Mark X. Caddick, Silke Busch, Meray Baştürkmen, Michael Freitag, Sam Griffiths-Jones, Stephen A. Osmani

Publikováno v: Nature
Nature, Nature Publishing Group, 2005, 438 (7071), pp.1105-1115. ⟨10.1038/nature04341⟩
Nature, 2005, 438 (7071), pp.1105-1115. ⟨10.1038/nature04341⟩

International audience; The aspergilli comprise a diverse group of filamentous fungi spanning over 200 million years of evolution. Here we report the genome sequence of the model organism Aspergillus nidulans, and a comparative study with Aspergillus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9c31c34471cf5b57d5e81cf480f8b7
https://doi.org/10.1038/nature04341

Regulation of hisHF Transcription of Aspergillus nidulans by Adenine and Amino Acid Limitation

Autor: Eric Kübler, Oliver Valerius, Klaus Adler, Bernd Hoffmann, Oliver W. Draht, Gerhard H. Braus

Publikováno v: Fungal Genetics and Biology. 32:21-31

The hisHF gene of Aspergillus nidulans encodes imidazole–glycerole–phosphate (IGP) synthase, consisting of a glutamine amidotransferase and a cyclase domain. The enzyme catalyzes the fifth and sixth steps of histidine biosynthesis, which results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d350a1634367b74c4cb7ad1abf087326
https://doi.org/10.1006/fgbi.2000.1244

An eight-subunit COP9 signalosome with an intact JAMM motif is required for fungal fruit body formation

Autor: Gerhard H. Braus, Oliver Valerius, Sven Krappmann, Kerstin Helmstaedt, Elke U. Schwier, William N. Lipscomb, Özgür Bayram, Krystyna Nahlik, Oliver W. Draht, Silke Busch

Fruit body formation in filamentous fungi is a complex and yet hardly understood process. We show here that protein turnover control is crucial for Aspergillus nidulans development. Deletion of genes encoding COP9 signalosome (CSN) subunits 1, 2, 4,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d354f33a2a2ca88cef1890d14e32bc
https://europepmc.org/articles/PMC1876576/

Integration of the catalytic subunit activates deneddylase activity in vivo as final step in fungal COP9 signalosome assembly.

Autor: Beckmann, Elena A., Köhler, Anna M., Meister, Cindy, Christmann, Martin, Draht, Oliver W., Rakebrandt, Nikolas, Valerius, Oliver, Braus, Gerhard H.

Publikováno v: Molecular Microbiology; Jul2015, Vol. 97 Issue 1, p110-124, 15p, 4 Diagrams, 2 Graphs