Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Oliver Vosyka"'
Autor:
Tobias Baumann, Oliver Vosyka, Bogdan Florea, Hermen Overkleeft, Silke Meiners, Ilona Kammerl
Publikováno v:
Bio-Protocol, Vol 6, Iss 24 (2016)
Activity-based probes (ABP) are small organic molecules that irreversibly bind to the active center of a specific enzyme family and may be coupled to a fluorophore or an affinity tag (Li et al., 2013). Here, we describe a method to pull-down active c
Externí odkaz:
https://doaj.org/article/9dbf4dbfd7674d02b1092f75aa82a53a
Autor:
Eliane V Wolf, Annett Zeißler, Oliver Vosyka, Evelyn Zeiler, Stephan Sieber, Steven H L Verhelst
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72307 (2013)
Rhomboids are intramembrane serine proteases that play diverse biological roles, including some that are of potential therapeutical relevance. Up to date, rhomboid inhibitor assays are based on protein substrate cleavage. Although rhomboids have an o
Externí odkaz:
https://doaj.org/article/70b1cebe224a4393822bbb3f7abd2254
Autor:
Ilona Kammerl, Silke Meiners, Holger Schulz, Marion Frankenberger, A Koch, Juliane Merl-Pham, Sophie Hardy, Julia Peierl, Yuqin Wang, Andrea Urmann, Claudia Flexeder, Jürgen Behr, Oliver Vosyka, Charles Pilette, Katrin Milger, Stefanie M. Hauck
Publikováno v:
Eur. Respir. J. 59:2101798 (2021)
The European respiratory journal, Vol. 59, no.3, p. 1-13 (2022)
The European respiratory journal, Vol. 59, no.3, p. 1-13 (2022)
BackgroundImmune cells contain a specialised type of proteasome, i.e. the immunoproteasome, which is required for intracellular protein degradation. Immunoproteasomes are key regulators of immune cell differentiation, inflammatory activation and auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30754803abf4ba5dcd23b42ea0310aa7
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63113
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63113
Autor:
Susanne Krauss-Etschmann, Alessandra Mossina, Tobias Straub, Oliver Vosyka, Dorothee Brech, Petra Nathan, Darcy E. Wagner, Rudolf Hatz, Hermen S. Overkleeft, Ivan O. Rosas, Elfriede Noessner, Gerhard Preissler, Ali Önder Yildirim, Hauke Winter, Ilona Kammerl, Antje Prasse, Thomas M. Conlon, Oliver Eickelberg, Melanie Königshoff, Katharina Heinzelmann, Christina Lukas, Angela Dann, Silke Meiners, Michael Lindner, Jürgen Behr
Publikováno v:
American journal of respiratory and critical care medicine
American journal of respiratory and critical care medicine, 193(11), 1230-1241
American journal of respiratory and critical care medicine, 193(11), 1230-1241
RATIONALE\nChronic obstructive pulmonary disease patients and in particular smokers are more susceptible to respiratory infections contributing to acute exacerbations of disease. The immunoproteasome is a specialized type of proteasome destined to im
Autor:
Oliver Eickelberg, Silke Meiners, Ilona Kammerl, Stefanie M. Hauck, Julia Schimmer, Oliver Vosyka
Publikováno v:
Airway Cell Biology and Immunopathology.
The immunoproteasome is the main proteolytic machinery in immune cells and essential for resolution of viral infections by increasing the quality of major histocompatibility class I antigen presentation. We have recently shown that immunoproteasome a
Autor:
Oliver Eickelberg, Oliver Vosyka, Herman S. Overkleeft, Youjia Yu, Martin Irmler, T. Stoeger, S Chen, Yiquan Wu, Johannes Beckers, Tobias Baumann, Ilona Kammerl, Silke Meiners
Publikováno v:
Cell Death Differ. 23, 1026-1037 (2016)
The proteasome is a central regulatory hub for intracellular signaling by degrading numerous signaling mediators. Immunoproteasomes are specialized types of proteasomes involved in shaping adaptive immune responses, but their role in innate immune si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e1b033d915694010cd8b461000e728
http://hdl.handle.net/1887/3199868
http://hdl.handle.net/1887/3199868
Autor:
Matthias Berg, Enrique Flores, Suncana Moslavac, Enrico Schleiff, Oliver Vosyka, Oliver Mirus, Veronika Reisinger, Matthias Plöscher, Lutz A. Eichacker
Publikováno v:
bchm. 388:823-829
Anabaena sp. PCC 7120 is a filamentous cyanobacterium that serves as a model to analyze prokaryotic cell differentiation, evolutionary development of plastids, and the regulation of nitrogen fixation. The cell wall is the cellular structure in contac
Autor:
Martijn Verdoes, Hermen S. Overkleeft, Clemens Ruppert, Serge Adnot, Elisabeth Marcos, Andreas Günther, Susanne Herold, Oliver Vosyka, Burkhardt Dahlmann, Stefanie M. Hauck, Lianne I. Willems, Ilona Keller, Shinji Takenaka, Heiko Adler, Shinji Ohno, Silke Meiners, Alexander Kloß, Oliver Eickelberg
Publikováno v:
Scientific Reports, 5, 10230
Sci. Rep. 5:10230 (2015)
Scientific Reports
Scientific Reports, 5
Sci. Rep. 5:10230 (2015)
Scientific Reports
Scientific Reports, 5
Contains fulltext : 152662.pdf (Publisher’s version ) (Open Access) Impaired immune function contributes to the development of chronic obstructive pulmonary disease (COPD). Disease progression is further exacerbated by pathogen infections due to im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98620dd830e949c1eb56e4df59ff4ad8
http://hdl.handle.net/1887/49468
http://hdl.handle.net/1887/49468
Autor:
Steven H. L. Verhelst, Stephan A. Sieber, Oliver Vosyka, Eliane V. Wolf, Annett Zeißler, Evelyn Zeiler
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72307 (2013)
PLoS ONE
PLoS ONE
Rhomboids are intramembrane serine proteases that play diverse biological roles, including some that are of potential therapeutical relevance. Up to date, rhomboid inhibitor assays are based on protein substrate cleavage. Although rhomboids have an o
Publikováno v:
Current opinion in chemical biology. 17(1)
Covalent chemical probes enable investigation of a desired fraction of the proteome. It is possible to adjust the selectivity of these probes, so they either react with a certain amino acid in all proteins, a class of proteins or only a single protei