Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Oliver Trw"'
Autor:
Ayesha Noorani, Coorens Thh, Oliver Trw, Thomas J. Mitchell, Michael R. Stratton, Raheleh Rahbari, James Hewinson, Peter J. Campbell, Alex Cagan, Luiza Moore, Christopher J, Rashesh Sanghvi, Rebecca C. Fitzgerald, Neville Mdc, Philip S. Robinson, Inigo Martincorena, Yvette Hooks
Starting from the zygote, all cells in the developing and adult human body continuously acquire mutations. A mutation shared between two different cells implies a shared progenitor cell and can thus be used as a naturally occurring marker for lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6556a56a671440b18c411a8da2b715b
https://doi.org/10.1101/2020.11.25.397828
https://doi.org/10.1101/2020.11.25.397828
Autor:
Oliver TRW; Department of Histopathology and Cytology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire CB2 0QQ, United Kingdom to3@sanger.ac.uk sb31@sanger.ac.uk.; Wellcome Sanger Institute, Hinxton, Cambridgeshire CB10 1RQ, United Kingdom., Behjati S; Wellcome Sanger Institute, Hinxton, Cambridgeshire CB10 1RQ, United Kingdom to3@sanger.ac.uk sb31@sanger.ac.uk.; Department of Paediatrics, University of Cambridge, Cambridge, Cambridgeshire CB2 0QQ, United Kingdom.; Department of Paediatric Haematology and Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire CB2 0QQ, United Kingdom.
Publikováno v:
Cold Spring Harbor perspectives in medicine [Cold Spring Harb Perspect Med] 2024 Nov 01; Vol. 14 (11). Date of Electronic Publication: 2024 Nov 01.
Autor:
Treger TD; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Paediatrics, University of Cambridge, Cambridge, CB2 0QQ, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK., Lawrence JEG; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK., Anderson ND; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Coorens THH; Broad Institute of MIT and Harvard, Cambridge, 02142 MA, USA., Letunovska A; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Abby E; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Lee-Six H; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK., Oliver TRW; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK., Al-Saadi R; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Tullus K; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Morcrette G; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Hutchinson JC; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Rampling D; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Sebire N; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK., Pritchard-Jones K; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK., Young MD; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Mitchell TJ; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK.; Early Cancer Institute, University of Cambridge, Cambridge, CB2 0XZ, UK., Jones PH; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.; Department of Oncology, University of Cambridge, Cambridge, CB2 OXZ, UK., Tran M; Specialist Centre for Kidney Cancer, Royal Free Hospital, London, NW3 2QG, UK. m.tran@ucl.ac.uk.; Faculty of Medical Sciences, Division of Surgery and Interventional Science, University College London, London, NW3 2PS, UK. m.tran@ucl.ac.uk., Behjati S; Wellcome Sanger Institute, Hinxton, CB10 1SA, UK. sb31@sanger.ac.uk.; Department of Paediatrics, University of Cambridge, Cambridge, CB2 0QQ, UK. sb31@sanger.ac.uk.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK. sb31@sanger.ac.uk., Chowdhury T; UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK. Tanzina.Chowdhury@gosh.nhs.uk.; NIHR Great Ormond Street Hospital Biomedical Research Centre, London, WC1N 3JH, UK. Tanzina.Chowdhury@gosh.nhs.uk.
Publikováno v:
Nature communications [Nat Commun] 2023 Sep 25; Vol. 14 (1), pp. 5826. Date of Electronic Publication: 2023 Sep 25.
Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer.
Autor:
Li R; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Ferdinand JR; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK., Loudon KW; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK; Cambridge University Hospitals NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK., Bowyer GS; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK., Laidlaw S; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Muyas F; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Mamanova L; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Neves JB; UCL Division of Surgery and Interventional Science, Royal Free Hospital, London NW3 2PS, UK; Specialist Centre for Kidney Cancer, Royal Free Hospital, London NW3 2PS, UK., Bolt L; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Fasouli ES; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Lawson ARJ; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Young MD; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Hooks Y; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Oliver TRW; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK; Cambridge University Hospitals NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK., Butler TM; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Armitage JN; Cambridge University Hospitals NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK., Aho T; Cambridge University Hospitals NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK., Riddick ACP; Cambridge University Hospitals NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK., Gnanapragasam V; Cambridge University Hospitals NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK; Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK., Welsh SJ; Cambridge University Hospitals NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK., Meyer KB; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Warren AY; Cambridge University Hospitals NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK., Tran MGB; UCL Division of Surgery and Interventional Science, Royal Free Hospital, London NW3 2PS, UK; Specialist Centre for Kidney Cancer, Royal Free Hospital, London NW3 2PS, UK., Stewart GD; Cambridge University Hospitals NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK; Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK., Cortés-Ciriano I; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Behjati S; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK; Cambridge University Hospitals NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK., Clatworthy MR; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK; Cambridge University Hospitals NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK., Campbell PJ; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Teichmann SA; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK; Department of Physics, Cavendish Laboratory, JJ Thomson Avenue, Cambridge CB3 0HE, UK. Electronic address: st9@sanger.ac.uk., Mitchell TJ; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK; Cambridge University Hospitals NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK; Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK. Electronic address: tjm@sanger.ac.uk.
Publikováno v:
Cancer cell [Cancer Cell] 2022 Dec 12; Vol. 40 (12), pp. 1583-1599.e10. Date of Electronic Publication: 2022 Nov 23.
Autor:
Oliver TRW; Wellcome Sanger Institute, Hinxton, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Chappell L; Wellcome Sanger Institute, Hinxton, UK., Sanghvi R; Wellcome Sanger Institute, Hinxton, UK., Deighton L; Wellcome Sanger Institute, Hinxton, UK., Ansari-Pour N; Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Dentro SC; Wellcome Sanger Institute, Hinxton, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Young MD; Wellcome Sanger Institute, Hinxton, UK., Coorens THH; Wellcome Sanger Institute, Hinxton, UK., Jung H; Wellcome Sanger Institute, Hinxton, UK., Butler T; Wellcome Sanger Institute, Hinxton, UK., Neville MDC; Wellcome Sanger Institute, Hinxton, UK., Leongamornlert D; Wellcome Sanger Institute, Hinxton, UK., Sanders MA; Wellcome Sanger Institute, Hinxton, UK.; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands., Hooks Y; Wellcome Sanger Institute, Hinxton, UK., Cagan A; Wellcome Sanger Institute, Hinxton, UK., Mitchell TJ; Wellcome Sanger Institute, Hinxton, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Cortes-Ciriano I; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Warren AY; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Wedge DC; Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Manchester Cancer Research Centre, Division of Cancer Sciences, University of Manchester, Manchester, UK., Heer R; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle Urology, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Coleman N; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Pathology, University of Cambridge, Cambridge, UK., Murray MJ; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Pathology, University of Cambridge, Cambridge, UK., Campbell PJ; Wellcome Sanger Institute, Hinxton, UK., Rahbari R; Wellcome Sanger Institute, Hinxton, UK. rr11@sanger.ac.uk., Behjati S; Wellcome Sanger Institute, Hinxton, UK. sb31@sanger.ac.uk.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. sb31@sanger.ac.uk.; Department of Paediatrics, University of Cambridge, Cambridge, UK. sb31@sanger.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2022 Aug 11; Vol. 13 (1), pp. 4272. Date of Electronic Publication: 2022 Aug 11.
Autor:
Coorens THH; Wellcome Sanger Institute, Hinxton, UK., Oliver TRW; Wellcome Sanger Institute, Hinxton, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Sanghvi R; Wellcome Sanger Institute, Hinxton, UK., Sovio U; Department of Obstetrics and Gynaecology, University of Cambridge, NIHR Cambridge Biomedical Research Centre, Cambridge, UK., Cook E; Department of Obstetrics and Gynaecology, University of Cambridge, NIHR Cambridge Biomedical Research Centre, Cambridge, UK., Vento-Tormo R; Wellcome Sanger Institute, Hinxton, UK., Haniffa M; Wellcome Sanger Institute, Hinxton, UK.; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.; Department of Dermatology, Royal Victoria Infirmary, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Young MD; Wellcome Sanger Institute, Hinxton, UK., Rahbari R; Wellcome Sanger Institute, Hinxton, UK., Sebire N; Great Ormond Street Hospital for Children NHS Foundation Trust, NIHR Great Ormond Street Hospital Biomedical Research Centre, London, UK.; UCL Great Ormond Street Institute of Child Health, London, UK., Campbell PJ; Wellcome Sanger Institute, Hinxton, UK., Charnock-Jones DS; Department of Obstetrics and Gynaecology, University of Cambridge, NIHR Cambridge Biomedical Research Centre, Cambridge, UK. dscj1@cam.ac.uk.; Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK. dscj1@cam.ac.uk., Smith GCS; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. gcss2@cam.ac.uk.; Department of Obstetrics and Gynaecology, University of Cambridge, NIHR Cambridge Biomedical Research Centre, Cambridge, UK. gcss2@cam.ac.uk.; Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK. gcss2@cam.ac.uk., Behjati S; Wellcome Sanger Institute, Hinxton, UK. sb31@sanger.ac.uk.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. sb31@sanger.ac.uk.; Department of Paediatrics, University of Cambridge, Cambridge, UK. sb31@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2022 Mar; Vol. 603 (7901), pp. E17.
Autor:
Elmentaite R; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Kumasaka N; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Roberts K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Fleming A; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge, UK., Dann E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., King HW; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, UK., Kleshchevnikov V; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Dabrowska M; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Pritchard S; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Bolt L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Vieira SF; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Mamanova L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Huang N; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Perrone F; Department of Paediatrics, University of Cambridge, Cambridge, UK., Goh Kai'En I; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Lisgo SN; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Katan M; Structural and Molecular Biology, Division of Biosciences, University College London, London, UK., Leonard S; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Oliver TRW; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Hook CE; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Nayak K; Department of Paediatrics, University of Cambridge, Cambridge, UK., Campos LS; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Domínguez Conde C; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Stephenson E; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Engelbert J; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Botting RA; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Polanski K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., van Dongen S; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Patel M; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Morgan MD; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, UK.; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Marioni JC; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, UK.; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Bayraktar OA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Meyer KB; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., He X; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences and Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Barker RA; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences and Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Uhlig HH; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Department of Paediatrics, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK., Mahbubani KT; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, UK., Saeb-Parsy K; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, UK., Zilbauer M; Department of Paediatrics, University of Cambridge, Cambridge, UK.; Department of Paediatric Gastroenterology, Hepatology and Nutrition, Cambridge University Hospitals Trust, Cambridge, UK.; Wellcome-MRC Cambridge Stem Cell Institute, Anne McLaren Laboratory, University of Cambridge, Cambridge, UK., Clatworthy MR; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge, UK., Haniffa M; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., James KR; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. k.james@garvan.org.au.; Garvan Institute of Medical Research, The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia. k.james@garvan.org.au., Teichmann SA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. st9@sanger.ac.uk.; Theory of Condensed Matter Group, Cavendish Laboratory/Department of Physics, University of Cambridge, Cambridge, UK. st9@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2021 Sep; Vol. 597 (7875), pp. 250-255. Date of Electronic Publication: 2021 Sep 08.
Autor:
Moore L; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Cagan A; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Coorens THH; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Neville MDC; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Sanghvi R; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Sanders MA; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Department of Hematology, Erasmus University Medical Center, Rotterdam, Netherlands., Oliver TRW; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Leongamornlert D; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Ellis P; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Inivata, Cambridge, UK., Noorani A; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Mitchell TJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Department of Surgery, University of Cambridge, Cambridge, UK., Butler TM; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Hooks Y; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Warren AY; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Jorgensen M; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Dawson KJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Menzies A; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., O'Neill L; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Latimer C; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Teng M; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., van Boxtel R; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Utrecht, Netherlands., Iacobuzio-Donahue CA; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Martincorena I; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Heer R; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle Urology, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Campbell PJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Fitzgerald RC; MRC Cancer Unit, University of Cambridge, Cambridge, UK., Stratton MR; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK. mrs@sanger.ac.uk., Rahbari R; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK. rr11@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2021 Sep; Vol. 597 (7876), pp. 381-386. Date of Electronic Publication: 2021 Aug 25.
Autor:
Coorens THH; Wellcome Sanger Institute, Hinxton, UK., Moore L; Wellcome Sanger Institute, Hinxton, UK.; Department of Pathology, University of Cambridge, Cambridge, UK., Robinson PS; Wellcome Sanger Institute, Hinxton, UK.; Department of Paediatrics, University of Cambridge, Cambridge, UK., Sanghvi R; Wellcome Sanger Institute, Hinxton, UK., Christopher J; Wellcome Sanger Institute, Hinxton, UK.; Department of Paediatrics, University of Cambridge, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Hewinson J; Wellcome Sanger Institute, Hinxton, UK., Przybilla MJ; Wellcome Sanger Institute, Hinxton, UK., Lawson ARJ; Wellcome Sanger Institute, Hinxton, UK., Spencer Chapman M; Wellcome Sanger Institute, Hinxton, UK.; Department of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Cagan A; Wellcome Sanger Institute, Hinxton, UK., Oliver TRW; Wellcome Sanger Institute, Hinxton, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Neville MDC; Wellcome Sanger Institute, Hinxton, UK., Hooks Y; Wellcome Sanger Institute, Hinxton, UK., Noorani A; Wellcome Sanger Institute, Hinxton, UK., Mitchell TJ; Wellcome Sanger Institute, Hinxton, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Surgery, University of Cambridge, Cambridge, UK., Fitzgerald RC; MRC Cancer Unit, University of Cambridge, Biomedical Campus, Cambridge, UK., Campbell PJ; Wellcome Sanger Institute, Hinxton, UK., Martincorena I; Wellcome Sanger Institute, Hinxton, UK., Rahbari R; Wellcome Sanger Institute, Hinxton, UK., Stratton MR; Wellcome Sanger Institute, Hinxton, UK. mrs@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2021 Sep; Vol. 597 (7876), pp. 387-392. Date of Electronic Publication: 2021 Aug 25.
Autor:
Young MD; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. my4@sanger.ac.uk., Mitchell TJ; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Surgery, University of Cambridge, Cambridge, UK., Custers L; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., Margaritis T; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Morales-Rodriguez F; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., Kwakwa K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Khabirova E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Kildisiute G; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Oliver TRW; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., de Krijger RR; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., van den Heuvel-Eibrink MM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Comitani F; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada., Piapi A; UCL Great Ormond Street Hospital Institute of Child Health, London, UK., Bugallo-Blanco E; UCL Great Ormond Street Hospital Institute of Child Health, London, UK., Thevanesan C; UCL Great Ormond Street Hospital Institute of Child Health, London, UK., Burke C; UCL Great Ormond Street Hospital Institute of Child Health, London, UK., Prigmore E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Ambridge K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Roberts K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Braga FAV; Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Coorens THH; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Del Valle I; UCL Great Ormond Street Hospital Institute of Child Health, London, UK., Wilbrey-Clark A; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Mamanova L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Stewart GD; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Surgery, University of Cambridge, Cambridge, UK., Gnanapragasam VJ; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge Urology Translational Research and Clinical Trials office, Cambridge Biomedical Campus Cambridge CB2 0QQ University of Cambridge, Cambridge, UK., Rampling D; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Sebire N; NIHR Great Ormond Street Hospital BRC and Institute of Child Health, London, UK., Coleman N; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Pathology, University of Cambridge, Cambridge, UK., Hook L; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Pathology, University of Cambridge, Cambridge, UK., Warren A; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Haniffa M; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.; Intitute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK., Kool M; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Hopp Children´s Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Division of Pediatric Neurooncology, Heidelberg, Germany., Pfister SM; Hopp Children´s Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Division of Pediatric Neurooncology, Heidelberg, Germany.; Heidelberg University Hospital, Department of Pediatric Hematology and Oncology, Heidelberg, Germany., Achermann JC; UCL Great Ormond Street Hospital Institute of Child Health, London, UK., He X; MRC-WT Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Clinical Neuroscience, University of Cambridge, Cambridge, UK., Barker RA; MRC-WT Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Clinical Neuroscience, University of Cambridge, Cambridge, UK., Shlien A; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada., Bayraktar OA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Teichmann SA; 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Publikováno v:
Nature communications [Nat Commun] 2021 Jun 23; Vol. 12 (1), pp. 3896. Date of Electronic Publication: 2021 Jun 23.