Associations between baseline characteristics, CD4 cell count response and virological failure on first-line efavirenz + tenofovir + emtricitabine for HIV

Autor: Oliver T. Stirrup, Caroline A. Sabin, Andrew N. Phillips, Ian Williams, Duncan Churchill, Anna Tostevin, Teresa Hill, David T. Dunn, David Asboe, Anton Pozniak, Patricia Cane, David Chadwick, Duncan Clark, Simon Collins, Valerie Delpech, Samuel Douthwaite, David Dunn, Esther Fearnhill, Kholoud Porter, Oliver Stirrup, Christophe Fraser, Anna Maria Geretti, Rory Gunson, Antony Hale, Stéphane Hué, Linda Lazarus, Andrew Leigh-Brown, Tamyo Mbisa, Nicola Mackie, Chloe Orkin, Eleni Nastouli, Deenan Pillay, Andrew Phillips, Caroline Sabin, Erasmus Smit, Kate Templeton, Peter Tilston, Erik Volz, Hongyi Zhang, Keith Fairbrother, Justine Dawkins, Siobhan O’Shea, Jane Mullen, Alison Cox, Richard Tandy, Tracy Fawcett, Mark Hopkins, Clare Booth, Lynne Renwick, Matthias L. Schmid, Brendan Payne, Jonathan Hubb, Simon Dustan, Stuart Kirk, Amanda Bradley-Stewart, Sophie Jose, Alicia Thornton, Susie Huntington, Adam Glabay, Shaadi Shidfar, Janet Lynch, James Hand, Carl de Souza, Nicky Perry, Stuart Tilbury, Elaney Youssef, Brian Gazzard, Mark Nelson, Tracey Mabika, Sundhiya Mandalia, Jane Anderson, Sajid Munshi, Frank Post, Ade Adefisan, Chris Taylor, Zachary Gleisner, Fowzia Ibrahim, Lucy Campbell, Kirsty Baillie, Richard Gilson, Nataliya Brima, Jonathan Ainsworth, Achim Schwenk, Sheila Miller, Chris Wood, Margaret Johnson, Mike Youle, Fiona Lampe, Colette Smith, Rob Tsintas, Clinton Chaloner, Samantha Hutchinson, John Walsh, Nicky Mackie, Alan Winston, Jonathan Weber, Farhan Ramzan, Mark Carder, Clifford Leen, Alan Wilson, Sheila Morris, Mark Gompels, Sue Allan, Adrian Palfreeman, Adam Lewszuk, Stephen Kegg, Akin Faleye, Victoria Ogunbiyi, Sue Mitchell, Phillip Hay, Christian Kemble, Fabiola Martin, Sarah Russell-Sharpe, Janet Gravely, Sris Allan, Andrew Harte, Anjum Tariq, Hazel Spencer, Ron Jones, Jillian Pritchard, Shirley Cumming, Claire Atkinson, Dushyant Mital, Veronica Edgell, Juli Allen, Andy Ustianowski, Cynthia Murphy, Ilise Gunder, Roy Trevelion, Abdel Babiker

Publikováno v: Journal of Virus Eradication, Vol 5, Iss 4, Pp 204-211 (2019)

Objectives: The aim of this study was to investigate associations between baseline characteristics and CD4 cell count response on first-line antiretroviral therapy and risk of virological failure (VF) with or without drug resistance. Methods: We cond

Externí odkaz: https://doaj.org/article/b685ef625be34b15b9ad4ef446718de6

Risk factors and outcomes for the Q151M and T69 insertion HIV-1 resistance mutations in historic UK data

Autor: Oliver T. Stirrup, David T. Dunn, Anna Tostevin, Caroline A. Sabin, Anton Pozniak, David Asboe, Alison Cox, Chloe Orkin, Fabiola Martin, Patricia Cane, the UK HIV Drug Resistance Database, the UK Collaborative HIV Cohort

Publikováno v: AIDS Research and Therapy, Vol 15, Iss 1, Pp 1-14 (2018)

Abstract Background The prevalence of HIV-1 resistance to antiretroviral therapies (ART) has declined in high-income countries over recent years, but drug resistance remains a substantial concern in many low and middle-income countries. The Q151M and

Externí odkaz: https://doaj.org/article/d7d3d338886b401788882d4686d70760

The Alpha Variant B.1.1.7 Was Not Associated With Excess Healthcare Acquired COVID-19 Infection in a Multi-Centre UK Hospital Study

Autor: Florencia A.T. Tettamanti, Cristina Venturini, Oliver T. Stirrup, José Afonso Guerra-Assuncao, Adela Alcolea-Medina, Angela H. Becket, Matthew Byott, Themoula Charalampous, Ana da Silva Filipe, Dan Frampton, Sharon Glaysher, Tabassum Khan, Raghavendran Kulasegara-Shylini, Beatrix Kele, Irene M. Monahan, Guy Mollett, Matthew D. Parker, Emanuela Pelosi, Paul Randell, Sunando Roy, Joshua F. Taylor, Sophie J. Weller, Eleri Wilson-Davies, Phillip Wade, Rachel Williams, COG-UK HOCI Variant Substudy Consortium, Andrew Copas, Teresa Cutino-Moguel, Nick Freemantle, Andrew C Hayward, Alison Holmes, Joseph Hughes Hughes, Tabitha W. Mahungu, Gaia Nebbia, Eleni Nastouli, David G. Partridge, Cassie F. Pope, James R. Price, Samuel C. Robson, Kordo Saeed, Gee Yen Shin, Thushan I. de Silva, Luke B. Snell, Emma C. Thomson, Adam A. Witney, Judith Breuer

Publikováno v: SSRN Electronic Journal.

Background: Recently emerging SARS-CoV-2 variants have been associated with an increased rate of transmission within the community. Little is known about the impact their increased infectivity has on transmission within hospitals. Methods: We collect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9856c355774003a84467ea7d9a26e77c
https://doi.org/10.2139/ssrn.3893562

Estimation of delay to diagnosis and incidence in HIV using indirect evidence of infection dates

Autor: Oliver T, Stirrup, David T, Dunn

Publikováno v: BMC Medical Research Methodology

Background Minimisation of the delay to diagnosis is critical to achieving optimal outcomes for HIV patients and to limiting the potential for further onward infections. However, investigation of diagnosis delay is hampered by the fact that in most n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fdf3fa5b0c3a8b8c348640ff36a52f7e
https://pubmed.ncbi.nlm.nih.gov/29945571