Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Oliver Stehling"'
Autor:
Laura Zein, Josina Grossmann, Helena Swoboda, Christina Borgel, Bernhard Wilke, Stephan Awe, Andrea Nist, Thorsten Stiewe, Oliver Stehling, Sven-Andreas Freibert, Till Adhikary, Ho-Ryun Chung
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
It has remained yet unclear which soluble factors regulate the anti-inflammatory macrophage phenotype observed in both homeostasis and tumourigenesis. We show here that haptoglobin, a major serum protein with elusive immunoregulatory properties, bind
Externí odkaz:
https://doaj.org/article/507e4731fed9448d9eeb658de17cc758
Autor:
Paul J. J. Mandigers, Oliver Stehling, Manon Vos-Loohuis, Frank G. Van Steenbeek, Roland Lill, Peter A. Leegwater
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Hereditary necrotizing myelopathy (HNM) in young Kooiker dogs is characterized by progressive ataxia and paralysis with autosomal recessive inheritance. The basic genetic defect is unknown. We investigated the possible cause by a genome
Externí odkaz:
https://doaj.org/article/d1325bf7daab4901ab61cf1d7d57bde5
Autor:
Sven-A. Freibert, Michal T. Boniecki, Claudia Stümpfig, Vinzent Schulz, Nils Krapoth, Dennis R. Winge, Ulrich Mühlenhoff, Oliver Stehling, Miroslaw Cygler, Roland Lill
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
[2Fe-2S] protein cofactors are essential for life and are synthesized on ISCU2 scaffolds. Here, the authors show that hydrophobic interaction of two conserved N-terminal tyrosines induces ISCU2 dimerization and concomitant [2Fe-2S] cluster synthesis.
Externí odkaz:
https://doaj.org/article/c031fda3199f4ae4ade00e57b4490d02
Autor:
Roland Lill, Oliver Stehling
Publikováno v:
HemaSphere, Vol 2, Pp 76-79 (2018)
Externí odkaz:
https://doaj.org/article/df1b09c1da614f518152bfa90f15ae5c
Autor:
Vinzent Schulz, Somsuvro Basu, Sven-A. Freibert, Holger Webert, Linda Boss, Ulrich Mühlenhoff, Fabien Pierrel, Lars-O. Essen, Douglas M. Warui, Squire J. Booker, Oliver Stehling, Roland Lill
Publikováno v:
Nature Chemical Biology. 19:206-217
Ferredoxins comprise a large family of iron-sulfur (Fe-S) proteins that shuttle electrons in diverse biological processes. Human mitochondria contain two isoforms of [2Fe-2S] ferredoxins, FDX1 (aka adrenodoxin) and FDX2, with known functions in cytoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1845ac316956605a467f82d2aea00d31
https://doi.org/10.1038/s41589-022-01159-4
https://doi.org/10.1038/s41589-022-01159-4
Autor:
Vinzent Schulz, Sven‐A. Freibert, Linda Boss, Ulrich Mühlenhoff, Oliver Stehling, Roland Lill
Publikováno v:
FEBS lettersReferences.
Ferredoxins (FDXs) comprise a large family of iron-sulfur proteins that shuttle electrons from NADPH and FDX reductases into diverse biological processes. This review focuses on the structure, function and specificity of mitochondrial [2Fe-2S] FDXs t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f880778dcb9b9b225b5004fc8aa811
https://pubmed.ncbi.nlm.nih.gov/36443530
https://pubmed.ncbi.nlm.nih.gov/36443530
Autor:
Laura Zein, Josina Grossmann, Helena Swoboda, Christina Borgel, Bernhard Wilke, Stephan Awe, Andrea Nist, Thorsten Stiewe, Oliver Stehling, Sven-Andreas Freibert, Till Adhikary, Ho-Ryun Chung
Haptoglobin is the major detoxifier of hemoglobin. Moreover, haptoglobin modulates the inflammatory responseviaNFκB. In some studies haptoglobin represses and in others it activates NFκB. We show here that these conflicting results are explainable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69dc39b05cc522ee670ea227f6a8cd4e
https://doi.org/10.1101/2022.11.22.516855
https://doi.org/10.1101/2022.11.22.516855
Publikováno v:
Encyclopedia of Inorganic and Bioinorganic Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8906678f113a6bbd0f9a358550dfb02f
https://doi.org/10.1002/9781119951438.eibc2741
https://doi.org/10.1002/9781119951438.eibc2741
Autor:
Dennis R. Winge, Michal T. Boniecki, Roland Lill, Claudia Stümpfig, Nils Krapoth, Ulrich Mühlenhoff, Sven-A. Freibert, Miroslaw Cygler, Vinzent Schulz, Oliver Stehling
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Synthesis of iron-sulfur (Fe/S) clusters in living cells requires scaffold proteins for both facile synthesis and subsequent transfer of clusters to target apoproteins. The human mitochondrial ISCU2 scaffold protein is part of the core ISC (iron-sulf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd98da6c606b1c19a366ee18ef91b637
http://europepmc.org/articles/PMC8617193
http://europepmc.org/articles/PMC8617193
Autor:
Fiorella Piemonte, Domenico De Rasmo, Enrico Bertini, Carlo Dionisi-Vici, Ralf Rösser, Oliver Stehling, Michela Di Nottia, Roland Lill, Daria Diodato, Daniela Verrigni, Alessandra Torraco, Teresa Rizza, Rosalba Carrozzo, Angelo Vozza, Claudia Stümpfig, Diego Martinelli, Giuseppe Fiermonte
Publikováno v:
Human molecular genetics
(2018). doi:10.1093/hmg/ddy183
info:cnr-pdr/source/autori:Torraco A, Stehling O, Stümpfig C, Rösser R, De Rasmo D, Fiermonte G, Verrigni D, Rizza T, Vozza A, Di Nottia M, Diodato D, Martinelli D, Piemonte F, Dionisi-Vici C, Bertini E, Lill R, Carrozzo R./titolo:ISCA1 Mutation In A Patient With Infantile-Onset Leukodystrophy Causes Defects In Mitochondrial [4Fe-4S] Proteins./doi:10.1093%2Fhmg%2Fddy183/rivista:Human molecular genetics (Print)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume
(2018). doi:10.1093/hmg/ddy183
info:cnr-pdr/source/autori:Torraco A, Stehling O, Stümpfig C, Rösser R, De Rasmo D, Fiermonte G, Verrigni D, Rizza T, Vozza A, Di Nottia M, Diodato D, Martinelli D, Piemonte F, Dionisi-Vici C, Bertini E, Lill R, Carrozzo R./titolo:ISCA1 Mutation In A Patient With Infantile-Onset Leukodystrophy Causes Defects In Mitochondrial [4Fe-4S] Proteins./doi:10.1093%2Fhmg%2Fddy183/rivista:Human molecular genetics (Print)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume
Multiple Mitochondrial Dysfunction Syndromes (MMDS) comprise a group of severe autosomal recessive diseases characterized by impaired respiration and lipoic acid metabolism, resulting in infantile-onset mitochondrial encephalopathy, non-ketotic hyper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9916550326ef78adbdae26f2fe5ff769
https://doi.org/10.1093/hmg/ddy183
https://doi.org/10.1093/hmg/ddy183