Zobrazeno 1 - 10
of 345
pro vyhledávání: '"Oliver Schilling"'
Autor:
Evgeniya Petrova, Jesús María López-Gay, Matthias Fahrner, Florent Leturcq, Jean-Pierre de Villartay, Claire Barbieux, Patrick Gonschorek, Lam C. Tsoi, Johann E. Gudjonsson, Oliver Schilling, Alain Hovnanian
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-24 (2024)
Abstract Netherton syndrome (NS) is a rare skin disease caused by loss-of-function mutations in the serine peptidase inhibitor Kazal type 5 (SPINK5) gene. Disease severity and the lack of efficacious treatments call for a better understanding of NS m
Externí odkaz:
https://doaj.org/article/a4b9cbf4d219401da0ec2c2e31fec3de
Autor:
Andreas R. Thomsen, Jörg Sahlmann, Peter Bronsert, Oliver Schilling, Felicia Poensgen, Annette M. May, Sylvia Timme-Bronsert, Anca-Ligia Grosu, Peter Vaupel, Jan-Olaf Gebbers, Gabriele Multhoff, Anne-Marie Lüchtenborg
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionBreast cancer is globally the leading cancer in women, and despite the high 5-year survival rate the most frequent cause of cancer related deaths. Surgery, systemic therapy and radiotherapy are the three pillars of curative breast cancer
Externí odkaz:
https://doaj.org/article/68426f8fb4c14447b9cf523b281d153a
Autor:
Sebastian Kistenmacher, Melanie Schwämmle, Gottfried Martin, Eva Ulrich, Stefan Tholen, Oliver Schilling, Andreas Gießl, Ursula Schlötzer-Schrehardt, Felicitas Bucher, Günther Schlunck, Irina Nazarenko, Thomas Reinhard, Naresh Polisetti
Publikováno v:
Cells, Vol 13, Iss 7, p 623 (2024)
Limbal epithelial progenitor cells (LEPC) rely on their niche environment for proper functionality and self-renewal. While extracellular vesicles (EV), specifically small EVs (sEV), have been proposed to support LEPC homeostasis, data on sEV derived
Externí odkaz:
https://doaj.org/article/cd3bcdc523f747d3bd412ebb516efc7d
Autor:
Patrick Malcolm Siegel, Bálint András Barta, Lukas Orlean, Ines Derya Steenbuck, Miguel Cosenza-Contreras, Tobias Wengenmayer, Georg Trummer, Dennis Wolf, Dirk Westermann, Oliver Schilling, Philipp Diehl
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is applied in patients with refractory hemodynamic failure. Exposure of blood components to high shear stress and the large extracorporeal surfaces in the ECMO circuit tr
Externí odkaz:
https://doaj.org/article/3df4b93d41e94a88856b9955ee9230e3
Autor:
Maren Nicole Stillger, Chia-Yi Chen, Zon Weng Lai, Mujia Li, Agnes Schäfer, Axel Pagenstecher, Christopher Nimsky, Jörg Walter Bartsch, Oliver Schilling
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-23 (2023)
Abstract Background Glioblastoma multiforme (GBM) is characterized by an unfavorable prognosis for patients affected. During standard-of-care chemotherapy using temozolomide (TMZ), tumors acquire resistance thereby causing tumor recurrence. Thus, dec
Externí odkaz:
https://doaj.org/article/bb7e3b7c0e0f41668975e51567ee9a33
Autor:
Subash C. Malik, Jia-Di Lin, Stephanie Ziegler-Waldkirch, Stefan Tholen, Sachin S. Deshpande, Marius Schwabenland, Oliver Schilling, Andreas Vlachos, Melanie Meyer-Luehmann, Christian Schachtrup
Publikováno v:
Cells, Vol 12, Iss 23, p 2757 (2023)
Nuclear pore complexes (NPCs) are highly dynamic macromolecular protein structures that facilitate molecular exchange across the nuclear envelope. Aberrant NPC functioning has been implicated in neurodegeneration. The translocated promoter region (Tp
Externí odkaz:
https://doaj.org/article/3e5461d4500d4580a304040de803716d
Autor:
Anne-Marie Lüchtenborg, Patrick Metzger, Miguel Cosenza Contreras, Victor Oria, Martin L. Biniossek, Franziska Lindner, Klemens Fröhlich, Ambrus Malyi, Thalia Erbes, Nicole Gensch, Jochen Maurer, Andreas Thomsen, Melanie Boerries, Oliver Schilling, Martin Werner, Peter Bronsert
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-15 (2022)
Abstract Background Ribosomal biogenesis and ribosomal proteins have attracted attention in the context of tumor biology in recent years. Instead of being mere translational machineries, ribosomes might play an active role in tumor initiation and pro
Externí odkaz:
https://doaj.org/article/fe86bccb7dfa47cca3bf5d88ffed6c71
Autor:
Patrick Bernhard, Berit Amelie Bretthauer, Sam Joé Brixius, Hannah Bügener, Johannes Elias Groh, Christian Scherer, Domagoj Damjanovic, Jörg Haberstroh, Georg Trummer, Christoph Benk, Friedhelm Beyersdorf, Oliver Schilling, Jan-Steffen Pooth
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background Only a small number of patients survive an out-of-hospital cardiac arrest (CA) and can be discharged from hospital alive with a large percentage of these patients retaining neurological impairments. In recent years, extracorporeal
Externí odkaz:
https://doaj.org/article/4866eeb3d28740908ead88ad88dda34c
Autor:
Klemens Fröhlich, Eva Brombacher, Matthias Fahrner, Daniel Vogele, Lucas Kook, Niko Pinter, Peter Bronsert, Sylvia Timme-Bronsert, Alexander Schmidt, Katja Bärenfaller, Clemens Kreutz, Oliver Schilling
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Data independent acquisition (DIA) has been gaining momentum in clinical proteomics. Here, the authors create a benchmark dataset comprising inter-patient heterogeneity to compare popular DIA data analysis workflows for identifying differentially abu
Externí odkaz:
https://doaj.org/article/17f2eb2214c94026859e0c88b1eb7fa8
Autor:
Janina Werner, Patrick Bernhard, Miguel Cosenza-Contreras, Niko Pinter, Matthias Fahrner, Prama Pallavi, Johannes Eberhard, Peter Bronsert, Felix Rückert, Oliver Schilling
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 36, Iss , Pp 100871- (2023)
Pancreatic ductal adenocarcinoma (PDAC) represents one of the most aggressive and lethal malignancies worldwide with an urgent need for new diagnostic and therapeutic strategies. One major risk factor for PDAC is the pre-indication of chronic pancrea
Externí odkaz:
https://doaj.org/article/4139db3688414143995d15f3aedeeb40