Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Oliver Rau"'
Autor:
Tobias Korn, Ulf-Peter Hansen, Tobias Sebastian Gabriel, Oliver Rauh, Nils Drexler, Indra Schroeder
Publikováno v:
Channels, Vol 18, Iss 1 (2024)
Kcv channels from plant viruses represent the autonomous pore module of potassium channels, devoid of any regulatory domains. These small proteins show very reproducible single-channel behavior in planar lipid bilayers. Thus, they are an optimum syst
Externí odkaz:
https://doaj.org/article/0764decc6bba4b45ac157ac441b73165
Autor:
Elena Poggio, Francesca Vallese, Andreas J. W. Hartel, Travis J. Morgenstern, Scott A. Kanner, Oliver Rauh, Flavia Giamogante, Lucia Barazzuol, Kenneth L. Shepard, Henry M. Colecraft, Oliver Biggs Clarke, Marisa Brini, Tito Calì
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-13 (2023)
Abstract Coronavirus disease (COVID-19) is a contagious respiratory disease caused by the SARS-CoV-2 virus. The clinical phenotypes are variable, ranging from spontaneous recovery to serious illness and death. On March 2020, a global COVID-19 pandemi
Externí odkaz:
https://doaj.org/article/6f24462f2be0478e821b38710e7c6258
Autor:
Saskia Wedel, Praveen Mathoor, Oliver Rauh, Tim Heymann, Cosmin I. Ciotu, Dominik C. Fuhrmann, Michael J. M. Fischer, Andreas Weigert, Natasja de Bruin, Felix Hausch, Gerd Geisslinger, Marco Sisignano
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-21 (2022)
Abstract Background Neuropathic pain is experienced worldwide by patients suffering from nerve injuries, infectious or metabolic diseases or chemotherapy. However, the treatment options are still limited because of low efficacy and sometimes severe s
Externí odkaz:
https://doaj.org/article/a1ae3ff5437d4071b8e640f89f13be07
Autor:
Georgia Tsagkogeorga, Helena Santos-Rosa, Andrej Alendar, Dan Leggate, Oliver Rausch, Tony Kouzarides, Hendrik Weisser, Namshik Han
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Machine learning of multi-modal data, including transcriptomic, proteomic, structural and physical interaction, predicts genes and molecular pathways involved in RNA methylation in humans.
Externí odkaz:
https://doaj.org/article/396efec7513649209949c08bf1dc3e5d
Autor:
Holger Stark, Mario Wurglics, Aleksandra Živković, Marika Hoffmann, Manfred Schubert-Zsilavecz, Gisbert Schneider, Khader Awwad, Bettina Hofmann, Thorsten J. Maier, Ingrid Fleming, Oliver Rau, Dieter Steinhilber, Carmen B. Rödl, Angela A.Y. Michel, Maren Pellowska, Matthias G. Wacker, Astrid S. Kahnt
Publikováno v:
British Journal of Pharmacology. 165:2304-2313
BACKGROUND AND PURPOSE The potency of many 5-lipoxygenase (5-LOX) inhibitors depends on the cellular peroxide tone and the mechanism of 5-LOX enzyme activation. Therefore, new inhibitors that act regardless of the mode of enzyme activation need to be
Autor:
Walter E. Müller, Manfred Schubert-Zsilavecz, Gunter P. Eckert, Michael Nöldner, Oliver Rau, Cornelia Franke, Mario Wurglics
Publikováno v:
Pharmacological Research. 61:234-241
Perilla frutescens seed oil (PFSO) represents a rich source of unsaturated fatty acids, especially of omega-3 linolenic acid and is commonly used as herbal food supplement with beneficial effects on the vascular system. The present study investigated
Autor:
Yvonne von Coburg, Jean-Claude Camelin, Jean-Charles Schwartz, Oliver Rau, Manfred Schubert-Zsilavecz, Kerstin Sander, Holger Stark, Xavier Ligneau
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:1581-1584
Antagonists of the human histamine H(3) receptor (hH(3)R) often contain a second basic moiety, which is well known to boost affinity on this histamine receptor subtype. Here, we prepared compounds with acidic moieties of different pK(a) values to fig
Autor:
Kirsten L. Stoffers, Sabine Seuter, Bernd L. Sorg, Olof Rådmark, Oliver Rau, Dieter Steinhilber
Publikováno v:
Journal of Molecular Biology. 395:884-896
5-Lipoxygenase (5-LO) gene expression is strongly upregulated during induction of myeloid cell differentiation by 1alpha,25-dihydroxyvitamin D(3) (calcitriol) and transforming growth factor-beta (TGFbeta) in a promoter-independent manner. In an activ
Autor:
Carlo Pergola, Oliver Werz, Arne Henkel, Manfred Schubert-Zsilavecz, Christine Greiner, Oliver Rau, Daniel Poeckel, Laura Popescu
Publikováno v:
European Journal of Pharmacology. 619:1-7
Pirinixic acid (Wy-14,643) is an agonist of the peroxisome proliferator-activated receptor (PPAR) subtype alpha exhibiting beneficial effects in various inflammation-related processes in a slow, long-termed fashion. We recently showed that alpha-subs
Autor:
Ewgenij Proschak, Karsten Siems, Manfred Schubert-Zsilavecz, Yusuf Tanrikulu, Gisbert Schneider, Oliver Schwarz, Lutz Müller-Kuhrt, Oliver Rau
Publikováno v:
ChemBioChem. 10:75-78