Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Oliver R. Maguire"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Transfer of scarce phosphate to organic molecules is a significant challenge for prebiotic chemistry. Here authors show a prebiotic physicochemical cycle to activate orthophosphate and via a kinetically stable, thermodynamically activated molecule ph
Externí odkaz:
https://doaj.org/article/d9969f1eb84948db95a22deaf1216812
Publikováno v:
Nature Communications
Nature Communications, 12, 1, pp. 1-9
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications, 12, 1-9
Nature Communications, 12, 1, pp. 1-9
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications, 12, 1-9
The incorporation of orthophosphate from scarce geochemical sources into the organic compounds essential for life under mild conditions is a fundamental challenge for prebiotic chemistry. Here we report a prebiotic system capable of overcoming this c
Autor:
Oliver R. Maguire, AnnMarie C. O'Donoghue, Matthew Rees, Steven L. Cobb, Bethany Taylor, Christopher J. Hayes, Eleanor M. Higgins, Nigel S. Simpkins
Publikováno v:
Chemical Science
The acidity of the α-proton in peptides has an essential role in numerous biochemical reactions and underpins their stereochemical integrity, which is critical to their biological function. We report a detailed kinetic and computational study of the
Autor:
William D. G. Brittain, Steven L. Cobb, Jiayun Zhu, Oliver R. Maguire, AnnMarie C. O'Donoghue, Alexander S. Hudson
Publikováno v:
Chemical Communications, 56, 45, pp. 6114-6117
Chemical Communications, 56, 6114-6117
Chemical Communications, 56, 6114-6117
Native chemical ligation (NCL) enables the chemical synthesis of peptides via reactions between N-terminal thiolates and C-terminal thioesters under mild, aqueous conditions at pH 7–8. Here we demonstrate quantitatively how thiol speciation at N-te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0856931ab29b90b5cb03377888c68d64
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/224942
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/224942
Autor:
Oliver R. Maguire, Albert S. Y. Wong, Mathieu G. Baltussen, Wilhelm T. S. Huck, Peer van Duppen, Aleksandr A. Pogodaev
Publikováno v:
Chemistry : a European Journal, 26, 1676-1682
Chemistry : a European Journal, 26, 7, pp. 1676-1682
Chemistry : a European Journal, 26, 7, pp. 1676-1682
Current efforts to design functional molecular systems have overlooked the importance of coupling out-of-equilibrium behaviour with changes in the environment. Here, the authors use an oscillating reaction network and demonstrate that the application
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4c874d1861e2a1acc5f2080c23bd4c
http://hdl.handle.net/2066/216023
http://hdl.handle.net/2066/216023
Publikováno v:
Chemical Communications, 56, 3725-3728
Chemical Communications, 56, 26, pp. 3725-3728
Chemical Communications, 56, 26, pp. 3725-3728
Complex systems such as ecosystems, the climate and stock markets produce emergent behaviour which is capable of undergoing dramatic change when pushed beyond a tipping point. Such complex systems display Early Warning Signals in their behaviour when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19924dfd00323a9473e0b7087825d71a
http://hdl.handle.net/2066/218824
http://hdl.handle.net/2066/218824
Autor:
Wilhelm T. S. Huck, Oliver R. Maguire
Publikováno v:
Emerging Topics in Life Sciences, 3, ETLS20190016
Emerging Topics in Life Sciences, 3, pp. ETLS20190016
Emerging Topics in Life Sciences, 3, pp. ETLS20190016
The goal of creating a synthetic cell necessitates the development of reaction networks which will underlie all of its behaviours. Recent developments in in vitro systems, based upon both DNA and enzymes, have created networks capable of a range of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0decfe17b0a572915f2ebc403dae58ca
http://hdl.handle.net/2066/214854
http://hdl.handle.net/2066/214854
Autor:
Oliver R. Maguire, Andrew D. Smith, Christopher J. Collett, AnnMarie C. O'Donoghue, Richard S. Massey, James E. Taylor
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (Weinheim an Der Bergstrasse, Germany)
Angewandte chemie international edition, 2015, Vol.54(23), pp.6887-6892 [Peer Reviewed Journal]
Angewandte Chemie (Weinheim an Der Bergstrasse, Germany)
Angewandte chemie international edition, 2015, Vol.54(23), pp.6887-6892 [Peer Reviewed Journal]
We thank the Royal Society for a University Research Fellowship (ADS), the EPSRC (CJC and RM) grant number EP/G013268/1 and the European Research Council under the European Union's Seventh Framework Programme (FP7/2007-2013) ERC grant agreement no 27
Homogeneous acid catalysis of nonasymmetric reactions continues to be an area of significant focus, and this chapter concentrates on recent relevant advances within a green chemistry context. The developments in acid catalysis are viewed through a nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::659a4127dca82143df5c281cd2e20958
https://doi.org/10.1039/9781782622093-00038
https://doi.org/10.1039/9781782622093-00038
Autor:
Richard S. Massey, Oliver R. Maguire, AnnMarie C. O'Donoghue, Andrew D. Smith, Andrei S. Batsanov, Christopher J. Collett
Publikováno v:
Chemical science, 2013, Vol.4(4), pp.1514-1522 [Peer Reviewed Journal]
The in situ observation, isolation and reversible formation of intermediate 3-(hydroxybenzyl) azolium salts derived from NHC addition to a range of substituted benzaldehydes is probed. Equilibrium constants for the formation of these 3-(hydroxybenzyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ecd2e531d78b56af5ce645137cd5099
https://hdl.handle.net/10023/3509
https://hdl.handle.net/10023/3509