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pro vyhledávání: '"Oliver P. T. Barrett"'
Autor:
Andrew K Marshall, Oliver P T Barrett, Timothy E Cullingford, Achchuthan Shanmugasundram, Peter H Sugden, Angela Clerk
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10027 (2010)
Cardiomyocyte hypertrophy is associated with changes in gene expression. Extracellular signal-regulated kinases 1/2 (ERK1/2) and RhoA [activated by hypertrophic agonists (e.g. endothelin-1)] regulate gene expression and are implicated in the response
Externí odkaz:
https://doaj.org/article/a5f889d6a8db46e181196577e51151c9
Autor:
Angela Clerk, Peter H. Sugden, Marcus J. Tindall, Alejandro Giraldo, Emre Amirak, Bonhi S. Bhattacharya, Stephen J. Fuller, Oliver P. T. Barrett
Publikováno v:
Biochemical Journal
Endothelin-1 promotes cardiomyocyte hypertrophy by inducing changes in gene expression. Immediate early genes including Atf3 (activating transcription factor 3), Egr1 (early growth response 1) and Ptgs2 (prostaglandin-endoperoxide synthase 2) are rap
In the heart, inflammatory cytokines including interleukin (IL) 1β are implicated in regulating adaptive and maladaptive changes, whereas IL33 negatively regulates cardiomyocyte hypertrophy and promotes cardioprotection. These agonists signal throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a2baf0b858f12f4091bdaa292b75e7
Publikováno v:
Methods in Molecular Biology ISBN: 9781617799792
Even though hematopoietic stem cells (HSC) are amongst the first somatic stem cells exploited for therapeutic purposes, their application is still limited by the inability to expand them ex vivo without impairing their function. Moreover, it has rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbbaa9095085f116a80356d57bba6c01
https://doi.org/10.1007/978-1-61779-980-8_18
https://doi.org/10.1007/978-1-61779-980-8_18
Autor:
Oliver P. T. Barrett, Jason W. Chin
Publikováno v:
Nucleic Acids Research
We developed orthogonal ribosome−mRNA pairs in which the orthogonal ribosome (O-ribosome) specifically translates the orthogonal mRNA and the orthogonal mRNA is not a substrate for cellular ribosomes. O-ribosomes have been used to create new cellul
Autor:
Oliver P. T. Barrett, Andrew K. Marshall, Angela Clerk, Timothy E. Cullingford, Achchuthan Shanmugasundram, Peter H. Sugden
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 4, p e10027 (2010)
PLoS ONE, Vol 5, Iss 4, p e10027 (2010)
BACKGROUND Cardiomyocyte hypertrophy is associated with changes in gene expression. Extracellular signal-regulated kinases 1/2 (ERK1/2) and RhoA [activated by hypertrophic agonists (e.g. endothelin-1)] regulate gene expression and are implicated in t