Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Oliver P Skinner"'
Autor:
Marcia A Munoz, Emma K Fletcher, Oliver P Skinner, Julie Jurczyluk, Esther Kristianto, Mark P Hodson, Shuting Sun, Frank H Ebetino, David R Croucher, Philip M Hansbro, Jacqueline R Center, Michael J Rogers
Publikováno v:
eLife, Vol 10 (2021)
Bisphosphonates drugs target the skeleton and are used globally for the treatment of common bone disorders. Nitrogen-containing bisphosphonates act by inhibiting the mevalonate pathway in bone-resorbing osteoclasts but, surprisingly, also appear to r
Externí odkaz:
https://doaj.org/article/efd2366c282f45e0a4b6b5d87db2968d
Autor:
Hyun Jae Lee, Marcela L. Moreira, Shihan Li, Takahiro Asatsuma, Cameron G. Williams, Oliver P. Skinner, Saba Asad, Michael Bramhall, Zhe Jiang, Zihan Liu, Ashlyn S. Kerr, Jessica A. Engel, Megan S. F. Soon, Jasmin Straube, Irving Barrera, Evan Murray, Fei Chen, Jason Nideffer, Prasanna Jagannathan, Ashraful Haque
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Children in malaria-endemic regions can experience repeated Plasmodium infections over short periods of time. Effects of re-infection on multiple co-existing CD4+ T cell subsets remain unresolved. Here, we examine antigen-experienced CD4+ T
Externí odkaz:
https://doaj.org/article/4d3cc96140c047edad0a1f3a0d29e9e7
Autor:
Cameron G. Williams, Marcela L. Moreira, Takahiro Asatsuma, Hyun Jae Lee, Shihan Li, Thomas N. Burn, Irving Barrera, Evan Murray, Megan S.F. Soon, Jessica A. Engel, David S. Khoury, Shirley Le, Brooke J. Wanrooy, Dominick Schienstock, Yannick O. Alexandre, Oliver P. Skinner, Rainon Joseph, Lynette Beattie, Scott N. Mueller, Fei Chen, Ashraful Haque
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114754- (2024)
Externí odkaz:
https://doaj.org/article/3eeba6fae4804717be2dfc45ba70fa91
Autor:
Lianne I. M. Lansink, Oliver P. Skinner, Jessica A. Engel, Hyun Jae Lee, Megan S. F. Soon, Cameron G. Williams, Arya SheelaNair, Clara P. S. Pernold, Pawat Laohamonthonkul, Jasmin Akter, Thomas Stoll, Michelle M. Hill, Arthur M. Talman, Andrew Russell, Mara Lawniczak, Xiaoxiao Jia, Brendon Chua, Dovile Anderson, Darren J. Creek, Miles P. Davenport, David S. Khoury, Ashraful Haque
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Maturation rates of malaria parasites within red blood cells (RBCs) can be influenced by host nutrient status and circadian rhythm; whether host inflammatory responses can also influence maturation remains less clear. Here, we observed that
Externí odkaz:
https://doaj.org/article/ad892e1e2d52402895cf3b6d1a593a65
Autor:
Marcia A. Munoz, Oliver P. Skinner, Etienne Masle-Farquhar, Julie Jurczyluk, Ya Xiao, Emma K. Fletcher, Esther Kristianto, Mark P. Hodson, Seán I. O’Donoghue, Sandeep Kaur, Robert Brink, David G. Zahra, Elissa K. Deenick, Kristen A. Perry, Avril A.B. Robertson, Sam Mehr, Pravin Hissaria, Catharina M. Mulders-Manders, Anna Simon, Michael J. Rogers
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 19 (2022)
Mevalonate kinase deficiency (MKD) is characterized by recurrent fevers and flares of systemic inflammation, caused by biallelic loss-of-function mutations in MVK. The underlying disease mechanisms and triggers of inflammatory flares are poorly under
Externí odkaz:
https://doaj.org/article/21b5b88799f3482d9c5c720c2d6c2ea8
Autor:
Hyun Jae Lee, Marcela L. Moreira, Shihan Li, Cameron G. Williams, Oliver P. Skinner, Saba Asad, Takahiro Asatsuma, Michael Bramhall, Zhe Jiang, Jessica A. Engel, Megan S. F. Soon, Jasmin Straube, Irving Barrera, Evan Murray, Fei Chen, Jason Nideffer, Prasanna Jagannathan, Ashraful Haque
Children in malaria-endemic regions can experience multiplePlasmodiuminfections over a short period of time, within vitroCD4+T cell recall responses becoming more regulatory with increasing age and exposure. This suggests that repeated infection qual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b3324488591cc43967f206bc5452275
https://doi.org/10.1101/2023.03.02.530907
https://doi.org/10.1101/2023.03.02.530907
Autor:
Cameron G. Williams, Marcela L. Moreira, Takahiro Asatsuma, Oliver P. Skinner, Hyun Jae Lee, Shihan Li, Irving Barrera, Evan Murray, Megan S. F. Soon, Jessica A. Engel, David S. Khoury, Saba Asad, Thiago Mass Steiner, Rainon Joseph, Yannick Alexandre, Scott N. Mueller, Fei Chen, Ashraful Haque
CD4+T cells orchestrate adaptive immunity to circulating malaria parasites; yet cellular interactions and molecular mechanisms controlling Th1 and Tfh differentiation in the spleen remain to be fully definedin vivo. Here, using a murine model of CD4-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20eb8a49595b6860a88ba3666cecec27
https://doi.org/10.1101/2023.02.23.529309
https://doi.org/10.1101/2023.02.23.529309
Autor:
Marcia A. Munoz, Oliver P. Skinner, Etienne Masle-Farquhar, Julie Jurczyluk, Ya Xiao, Emma Fletcher, Esther Kristianto, Mark P. Hodson, Seán I. O’Donoghue, Sandeep Kaur, Robert Brink, David Zahra, Elissa K. Deenick, Kristen Perry, Avril A.B. Robertson, Sam Mehr, Pravin Hissaria, Catharina M. Mulders-Manders, Anna Simon, Michael J. Rogers
SUMMARYMevalonate kinase deficiency (MKD) is caused by biallelic loss-of-function mutations in MVK, leading to recurrent fevers and systemic inflammation. We describe new mouse avatars of MKD bearing p.Val377Ile (the commonest variant) or deletions i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57df67c4d6564e93318f45df8c27f3bf
https://doi.org/10.1101/2022.02.28.480959
https://doi.org/10.1101/2022.02.28.480959
Autor:
Marcia A Munoz, Emma K Fletcher, Oliver P Skinner, Julie Jurczyluk, Esther Kristianto, Mark P Hodson, Shuting Sun, Frank H Ebetino, David R Croucher, Philip M Hansbro, Jacqueline R Center, Michael J Rogers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::516691d1ff3eaecf54341d1d13f4594d
https://doi.org/10.7554/elife.72430.sa2
https://doi.org/10.7554/elife.72430.sa2
Autor:
Avril A. B. Robertson, Paul J. Baker, Julie Jurczyluk, Oliver P Skinner, Kate Schroder, Seth L. Masters, Alicia G. Rios Wilks, Michael J. Rogers, Misaki S. Clearwater, Sam Mehr, Marcia A. Munoz
Publikováno v:
The Journal of allergy and clinical immunology. 143(6)