Oxidation-Specific Epitopes (OSEs) Dominate the B Cell Response in Murine Polymicrobial Sepsis

Autor: Oliver Nicolai, Christian Pötschke, Dina Raafat, Julia van der Linde, Sandra Quosdorf, Anna Laqua, Claus-Dieter Heidecke, Claudia Berek, Murthy N. Darisipudi, Christoph J. Binder, Barbara M. Bröker

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

In murine abdominal sepsis by colon ascendens stent peritonitis (CASP), a strong increase in serum IgM and IgG antibodies was observed, which reached maximum values 14 days following sepsis induction. The specificity of this antibody response was stu

Externí odkaz: https://doaj.org/article/82d4abd807bf4d98b6a1cfe8cfa8ea20

The renin-angiotensin system as a primary cause of polyarteritis nodosa in rats

Autor: John J. Mullins, Andrea Thiele, Beate Kuttler, Gerd Lorenz, Joerg Peters, Rainer Rettig, Barbara S. Peters, Oliver Nicolai, Andreas Beineke

Publikováno v: Journal of Cellular and Molecular Medicine
Peters, B S, Kuttler, B, Beineke, A, Lorenz, G, Thiele, A, Nicolai, O, Rettig, R, Mullins, J J & Peters, J 2010, ' The renin-angiotensin system as a primary cause of polyarteritis nodosa in rats ', Journal of Cellular and Molecular Medicine, vol. 14, no. 6a, pp. 1318-1327 . https://doi.org/10.1111/j.1582-4934.2009.00778.x

Polyarteritis nodosa is a necrotizing vasculitis of medium-sized arteries of unknown origin. Hypertension is present in 30% of patients with polyarteritis nodosa. In those cases, high renin levels are thought to be secondary to renal involvement. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435b489e641ad7fc0d16881a16fb2538
https://doi.org/10.1111/j.1582-4934.2009.00778.x