Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Oliver Merk"'
Autor:
W. Weikel, Rolf Kreienberg, Roland Moll, Liane Dreher, Volker Möbus, C.-D. Gerharz, Oliver Merk
Publikováno v:
Gynecologic Oncology. 83:523-532
Objectives. Cell lines are valuable in vitro models for clinical and basic research. Most ovarian cancer cell lines described are serous cystadenocarcinomas or poorly differentiated adenocarcinomas. The establishment of ovarian cancer cell lines with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06efccf2fde92c2cec7bfec7ff705b36
https://doi.org/10.1006/gyno.2001.6425
https://doi.org/10.1006/gyno.2001.6425
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 471:71-80
Modifications of the comet assay have been introduced to measure crosslinks by determining the reduction of induced DNA migration. Our previous results indicated that the modified protocol of the alkaline comet assay is a sensitive tool for the detec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3275b1b84c93684ca9722e796f6fa588
https://doi.org/10.1016/s1383-5718(00)00110-8
https://doi.org/10.1016/s1383-5718(00)00110-8
Autor:
I. B. Runnebaum, L. Dreher, Oliver Merk, Dirk G. Kieback, Volker Möbus, Roland Moll, S. Linner, R. Kreienberg, Claus-Dieter Gerharz, H.-J. Grill
Publikováno v:
International Journal of Cancer. 77:415-423
Permanent human tumor cell lines are an important tool for the study of breast cancer. Two new breast cancer cell lines (BrCa-MZ-01 and BrCa-MZ-02) were isolated from a solid tumor and a pleural effusion, respectively. One cell line was established f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46a83c0743972001a44ce6ba76d19798
https://doi.org/10.1002/(sici)1097-0215(19980729)77:3<415::aid-ijc18>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19980729)77:3<415::aid-ijc18>3.0.co
Autor:
Günter Speit, Oliver Merk
Publikováno v:
Environmental and Molecular Mutagenesis. 32:260-268
Formaldehyde (FA) is a genotoxic substance, induces tumors in the nasal epithelium of rats, and is suspected to be a human carcinogen. As a primary DNA lesion, FA induces DNA-protein crosslinks (DPC) and the formation of DPC has been used as a measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b74796077629985ab119c90a3c1ed9d2
https://doi.org/10.1002/(sici)1098-2280(1998)32:3<260::aid-em9>3.0.co
https://doi.org/10.1002/(sici)1098-2280(1998)32:3<260::aid-em9>3.0.co
Autor:
Günter Speit, Helga Fender, Günter Obe, Erich Gebhart, Irmgard Verdorfer, Oliver Merk, Gisela Wolf, Susann Neubauer, Andreas Rothfuß
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cd9666d8aea9559ed36282d80cc5905
https://doi.org/10.1002/9783527621026.ch5
https://doi.org/10.1002/9783527621026.ch5
Publikováno v:
Mutagenesis. 15(1)
We have previously shown that the alkaline Comet assay (single cell gel electrophoresis) in a modified version is a sensitive test for the detection of formaldehyde-induced DNA-protein crosslinks (DPC). Our results also indicated that formaldehyde-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2743026979d1efa99cfaf5aa5ffbb39
https://pubmed.ncbi.nlm.nih.gov/10640535
https://pubmed.ncbi.nlm.nih.gov/10640535
Publikováno v:
Environmental and molecular mutagenesis. 34(4)
Hyperbaric oxygen (HBO) treatment as used therapeutically (i.e., exposure to 100% oxygen at a pressure of 1.5 bar for a total of 60 min) has been shown to induce DNA damage in the alkaline comet assay with leukocytes from test subjects. Under these c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5990af81d9ae238bff1321c28c7d36a
https://pubmed.ncbi.nlm.nih.gov/10618178
https://pubmed.ncbi.nlm.nih.gov/10618178
Publikováno v:
Toxicology letters. 110(1-2)
The alkaline comet assay (single-cell gel electrophoresis) is becoming established as a genotoxicity test with many fold applications in vitro and in vivo. While the underlying principles are identical, various modifications of the method are in use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc01679b6f85135c353bf0acafe4a24a
https://pubmed.ncbi.nlm.nih.gov/10593597
https://pubmed.ncbi.nlm.nih.gov/10593597
Autor:
Oliver Merk, Günter Speit
Publikováno v:
Environmental and molecular mutagenesis. 33(2)
The alkaline comet assay is a sensitive test for the detection of a variety of DNA lesions. However, crosslinks are not readily detected under standard test conditions. Recently, modifications have been introduced measuring crosslinks by determining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030539d167201e9ee986e4b74319db02
https://pubmed.ncbi.nlm.nih.gov/10217071
https://pubmed.ncbi.nlm.nih.gov/10217071