Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Oliver Mauermann"'
Autor:
Christin Gasch, Theresa Oldopp, Oliver Mauermann, Tobias M. Gorges, Antje Andreas, Cornelia Coith, Volkmar Müller, Tanja Fehm, Wolfgang Janni, Klaus Pantel, Sabine Riethdorf
Publikováno v:
Molecular Oncology, Vol 10, Iss 8, Pp 1330-1343 (2016)
Modern technologies enable detection and characterization of circulating tumor cells (CTC) in peripheral blood samples. Thus, CTC have attracted interest as markers for therapeutic response in breast cancer. First studies have incorporated CTC analys
Externí odkaz:
https://doaj.org/article/499896484b9d481ea6c3ea8c89fa11f2
Autor:
Michael R. Speicher, Jochen B. Geigl, Thomas Bauernhofer, Sabine Riethdorf, Klaus Pantel, Hellmut Samonigg, Heinz Sill, Florian Eisner, Gerald Höfler, Carolin Lackner, Oliver Mauermann, Julie Waldispuehl-Geigl, Sigurd Lax, Eva Maria Hoffmann, Peter Ulz, Martin Pichler, Christin Gasch, Martina Auer, Ellen Heitzer
PDF file - 868K, Ratio bin distributions for CTC12 (a) and CTC03 (b) from patient #6. The large bin 13 peak indicates the frequency of oligonucleotides with balanced ratio values. The bins to the right of 13 represent the bins for oligonucleotides wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea437c6888af3ac054ca1f47004d381
https://doi.org/10.1158/0008-5472.22398300
https://doi.org/10.1158/0008-5472.22398300
Autor:
Michael R. Speicher, Jochen B. Geigl, Thomas Bauernhofer, Sabine Riethdorf, Klaus Pantel, Hellmut Samonigg, Heinz Sill, Florian Eisner, Gerald Höfler, Carolin Lackner, Oliver Mauermann, Julie Waldispuehl-Geigl, Sigurd Lax, Eva Maria Hoffmann, Peter Ulz, Martin Pichler, Christin Gasch, Martina Auer, Ellen Heitzer
PDF file - 95K, List of 68 genes, which, according to the COSMIC database, are frequently mutated in colorectal carcinoma (CRC) and analyzed in our study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b6d8d30c3e6a4af6e490764f2583e7
https://doi.org/10.1158/0008-5472.22398288
https://doi.org/10.1158/0008-5472.22398288
Autor:
Michael R. Speicher, Jochen B. Geigl, Thomas Bauernhofer, Sabine Riethdorf, Klaus Pantel, Hellmut Samonigg, Heinz Sill, Florian Eisner, Gerald Höfler, Carolin Lackner, Oliver Mauermann, Julie Waldispuehl-Geigl, Sigurd Lax, Eva Maria Hoffmann, Peter Ulz, Martin Pichler, Christin Gasch, Martina Auer, Ellen Heitzer
PDF file - 1303K, Evaluation of available material from patient #9. (a-b) Array CGH profiles of the primary tumor (a) and metastasis (peritoneal carcinomatosis) (b). Regarding the color bar codes please see legend to Supp. Fig. 2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734922995c2c4dfe4759f70b2080f593
https://doi.org/10.1158/0008-5472.22398312
https://doi.org/10.1158/0008-5472.22398312
Autor:
Michael R. Speicher, Jochen B. Geigl, Thomas Bauernhofer, Sabine Riethdorf, Klaus Pantel, Hellmut Samonigg, Heinz Sill, Florian Eisner, Gerald Höfler, Carolin Lackner, Oliver Mauermann, Julie Waldispuehl-Geigl, Sigurd Lax, Eva Maria Hoffmann, Peter Ulz, Martin Pichler, Christin Gasch, Martina Auer, Ellen Heitzer
PDF file - 188K, Sequencing of UCR41 and flanking regions: UCR41 is a 217-bp-long ultra-conserved region depicted in dark green. The gray bar indicates the extremely conserved sequence. The region is flanked by two SNPs that are frequent in the Europ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45eb3280c73d66a4f3223c50c208134
https://doi.org/10.1158/0008-5472.22398303.v1
https://doi.org/10.1158/0008-5472.22398303.v1
Autor:
Michael R. Speicher, Jochen B. Geigl, Thomas Bauernhofer, Sabine Riethdorf, Klaus Pantel, Hellmut Samonigg, Heinz Sill, Florian Eisner, Gerald Höfler, Carolin Lackner, Oliver Mauermann, Julie Waldispuehl-Geigl, Sigurd Lax, Eva Maria Hoffmann, Peter Ulz, Martin Pichler, Christin Gasch, Martina Auer, Ellen Heitzer
PDF file - 346K, Analysis of CTC03 of patient #22: The array-CGH ratio profile demonstrates losses on chromosomes 3, 4, 5, 8p, and 18 and gains on chromosomes 7p, 17q, and 20.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1811a1b001a59073b3514c23597d1394
https://doi.org/10.1158/0008-5472.22398306
https://doi.org/10.1158/0008-5472.22398306
Autor:
Michael R. Speicher, Jochen B. Geigl, Thomas Bauernhofer, Sabine Riethdorf, Klaus Pantel, Hellmut Samonigg, Heinz Sill, Florian Eisner, Gerald Höfler, Carolin Lackner, Oliver Mauermann, Julie Waldispuehl-Geigl, Sigurd Lax, Eva Maria Hoffmann, Peter Ulz, Martin Pichler, Christin Gasch, Martina Auer, Ellen Heitzer
PDF file - 940K, Evaluation of available material from patient #6. (a-b) Array CGH profiles of the primary tumor (a) and metastasis (b). The multicolor bar codes at the top or bottom of the ratio profiles illustrate the results obtained during the it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5967a557133f4d7869a84f1523c98257
https://doi.org/10.1158/0008-5472.22398318
https://doi.org/10.1158/0008-5472.22398318
Autor:
Michael R. Speicher, Jochen B. Geigl, Thomas Bauernhofer, Sabine Riethdorf, Klaus Pantel, Hellmut Samonigg, Heinz Sill, Florian Eisner, Gerald Höfler, Carolin Lackner, Oliver Mauermann, Julie Waldispuehl-Geigl, Sigurd Lax, Eva Maria Hoffmann, Peter Ulz, Martin Pichler, Christin Gasch, Martina Auer, Ellen Heitzer
PDF file - 3383K, Calculation of different integer copy number profiles for CTC03 from patient #6 assuming diploidy (a), triploidy (b), or tetraploidy (c) and the respective array CGH profile (d).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea427013d8ee64643c553de8ea97fff
https://doi.org/10.1158/0008-5472.22398297.v1
https://doi.org/10.1158/0008-5472.22398297.v1
Autor:
Michael R. Speicher, Jochen B. Geigl, Thomas Bauernhofer, Sabine Riethdorf, Klaus Pantel, Hellmut Samonigg, Heinz Sill, Florian Eisner, Gerald Höfler, Carolin Lackner, Oliver Mauermann, Julie Waldispuehl-Geigl, Sigurd Lax, Eva Maria Hoffmann, Peter Ulz, Martin Pichler, Christin Gasch, Martina Auer, Ellen Heitzer
PDF file - 92K, Identification of mutations in cancer candidate (CAN) genes in patient samples using next-generation sequencing. Mutations that are shared between primary tumor and/or metastasis and/or CTCs are highlighted in bold.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e91445e44acc277f86a92e5c254d95
https://doi.org/10.1158/0008-5472.22398285.v1
https://doi.org/10.1158/0008-5472.22398285.v1
Autor:
Julie Waldispühl-Geigl, Gerold Schuler, Ingrid Moll, Sven Peine, Ellen Heitzer, Klaus Pantel, Sabine Riethdorf, Michael R. Speicher, Sonja Bergmann, Lucie Heinzerling, Nicole Fischer, Oliver Mauermann, Cornelia Coith, Lina Hildebrandt, Gerhard Schön
Publikováno v:
Clinical Chemistry. 65:462-472
BACKGROUND Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer with increasing incidence and high mortality rates. MCC has recently become the subject of immune checkpoint therapy, but reliable biomarkers for estimating prognosis, risk stra