Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Oliver Kobler"'
Autor:
Timo Saumweber, Astrid Rohwedder, Michael Schleyer, Katharina Eichler, Yi-chun Chen, Yoshinori Aso, Albert Cardona, Claire Eschbach, Oliver Kobler, Anne Voigt, Archana Durairaja, Nino Mancini, Marta Zlatic, James W. Truman, Andreas S. Thum, Bertram Gerber
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
The mushroom body of Drosophila integrates sensory information with past experience to guide behaviour. Here, the authors provide an atlas of the input and output neurons of the stage 3 larval mushroom body at the single-cell level, and analyse their
Externí odkaz:
https://doaj.org/article/4e1068b2dfaf4bfbac969f6d103d2933
Autor:
Kathrin Marter, Oliver Kobler, Ines Erdmann, Elaheh Soleimanpour, Peter Landgraf, Anke Müller, Julia Abele, Ulrich Thomas, Daniela Dieterich
Publikováno v:
Bio-Protocol, Vol 9, Iss 2 (2019)
Copper-catalyzed azide-alkyne-cycloaddition (CuAAC), also known as ‘click chemistry’ serves as a technique for bio-orthogonal, that is, bio-compatible labeling of macromolecules including proteins or lipids. Click chemistry has been widely used t
Externí odkaz:
https://doaj.org/article/e2134ed75b17462cb63dc182dddf63ca
Publikováno v:
Cell Reports, Vol 14, Iss 2, Pp 189-199 (2016)
The local synthesis of transmembrane proteins underlies functional specialization of dendritic microdomains in neuronal plasticity. It is unclear whether these proteins have access to the complete machinery of the secretory pathway following local sy
Externí odkaz:
https://doaj.org/article/965cd72e781647bab5bb81d26510338d
Autor:
Ines Erdmann, Kathrin Marter, Oliver Kobler, Sven Niehues, Julia Bussmann, Anke Müller, Julia Abele, Erik Storkebaum, Ulrich Thomas, Daniela Dieterich
Publikováno v:
Bio-Protocol, Vol 7, Iss 14 (2017)
Advanced mass spectrometry technology has pushed proteomic analyses to the forefront of biological and biomedical research. Limitations of proteomic approaches now often remain with sample preparations rather than with the sensitivity of protein dete
Externí odkaz:
https://doaj.org/article/4ea4aa54bf354413a015fea2563678b6
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97692 (2014)
Neuronal network formation depends on properly timed and localized generation of presynaptic as well as postsynaptic structures. Although of utmost importance for understanding development and plasticity of the nervous system and neurodegenerative di
Externí odkaz:
https://doaj.org/article/8e15342a9c6642c999665d13f7534f33
Autor:
Nino Mancini, Juliane Thoener, Esmeralda Tafani, Dennis Pauls, Oded Mayseless, Martin Strauch, Katharina Eichler, Andrew Champion, Oliver Kobler, Denise Weber, Edanur Sen, Aliće Weiglein, Volker Hartenstein, Andreas S. Thum, Astrid Rohwedder, Michael Schleyer, Bertram Gerber
Larvae of the fruit flyDrosophila melanogasterare a powerful study case for understanding the neural circuits underlying behavior. Indeed, the numerical simplicity of the larval brain has permitted the reconstruction of its synaptic connectome, and g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55b27499f6157b8854e21b398ad47144
https://doi.org/10.1101/2022.12.19.521052
https://doi.org/10.1101/2022.12.19.521052
Publikováno v:
Journal of neurogenetics, 35(3):306-319
Larval Drosophila are used as a genetically accessible study case in many areas of biological research. Here we report a fast, robust and user-friendly procedure for the whole-body multifluorescence imaging of Drosophila larvae; the protocol has been
Autor:
Stefanie Ryglewski, Martin Heine, Arthur Bikbaev, Aylin Pichler, Ulrich Thomas, Carsten Duch, Torsten W.B. Götz, Niklas Krick, Oliver Kobler
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences, 118(28):e2106621118
Proceedings of the National Academy of Sciences, 118(28):e2106621118
Significance Synaptic vesicle (SV) release from presynaptic terminals requires nanometer precise control of action potential (AP)–triggered calcium influx through voltage-gated calcium channels (VGCCs). SV recycling also depends on calcium signals,
Autor:
Robert Eckenstaler, Elke Edelmann, Thomas Endres, Tanja Brigadski, Klaus-Dieter Fischer, Beat Lutz, Karin Richter, Werner Zuschratter, Oliver Kobler, Julia Leschik, Thomas Munsch, Volkmar Lessmann
Publikováno v:
Molecular Neurobiology. 56:6833-6855
Brain-derived neurotrophic factor (BDNF) is a secreted messenger molecule that is crucial for neuronal function and induction of synaptic plasticity. Although altered availability of BDNF underlies many neurological deficits and neurodegenerative dis
Autor:
Durga Praveen Meka, Oliver Kobler, Shuai Hong, Carina Meta Friedrich, Souhaila Wuesthoff, Melad Henis, Birgit Schwanke, Christoph Krisp, Nessa Schmuelling, René Rueter, Tabitha Ruecker, Ewelina Betleja, Tao Cheng, Moe R. Mahjoub, Peter Soba, Hartmut Schlüter, Eugenio F. Fornasiero, Froylan Calderon de Anda
Publikováno v:
Cell reports, 39(3):110686
Microtubule (MT) modifications are critical during axon development, with stable MTs populating the axon. How these modifications are spatially coordinated is unclear. Here, via high-resolution microscopy, we show that early developing neurons have f