Zobrazeno 1 - 10
of 304
pro vyhledávání: '"Oliver Klein"'
Autor:
Maximilian Zimmer, Karl Herbert Hillebrandt, Nathalie Nora Roschke, Steffen Lippert, Oliver Klein, Grit Nebrich, Joseph Maria George Vernon Gassner, Felix Strobl, Johann Pratschke, Felix Krenzien, Igor Maximilian Sauer, Nathanael Raschzok, Simon Moosburner
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-14 (2024)
Abstract Background Liver grafts are frequently declined due to high donor age or age mismatch with the recipient. To improve the outcome of marginal grafts, we aimed to characterize the performance of elderly vs. young liver grafts in a standardized
Externí odkaz:
https://doaj.org/article/97915733214b4c90b2a9ed1e285a1b80
Autor:
Anna-Maria Diedrich, Assal Daneshgar, Peter Tang, Oliver Klein, Annika Mohr, Olachi A. Onwuegbuchulam, Sabine von Rueden, Kerstin Menck, Annalen Bleckmann, Mazen A. Juratli, Felix Becker, Igor M. Sauer, Karl H. Hillebrandt, Andreas Pascher, Benjamin Struecker
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract Background The extracellular matrix (ECM) is a three-dimensional network of proteins that encases and supports cells within a tissue and promotes physiological and pathological cellular differentiation and functionality. Understanding the co
Externí odkaz:
https://doaj.org/article/184b7542c395420292ac63157f983099
Autor:
Dipthi Bachamanda Somesh, Kristin Klose, Janita A. Maring, Désirée Kunkel, Karsten Jürchott, Stephanie I. Protze, Oliver Klein, Grit Nebrich, Matthias Becker, Ulrike Krüger, Timo Z. Nazari-Shafti, Volkmar Falk, Andreas Kurtz, Manfred Gossen, Christof Stamm
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Background Direct cardiac reprogramming is currently being investigated for the generation of cells with a true cardiomyocyte (CM) phenotype. Based on the original approach of cardiac transcription factor-induced reprogramming of fibroblasts
Externí odkaz:
https://doaj.org/article/c371854fe11c4e7097810a43c278f286
Autor:
Genevieve Dall, Cassandra J. Vandenberg, Ksenija Nesic, Gayanie Ratnayake, Wenying Zhu, Joseph H. A. Vissers, Justin Bedő, Jocelyn Penington, Matthew J. Wakefield, Damien Kee, Amandine Carmagnac, Ratana Lim, Kristy Shield-Artin, Briony Milesi, Amanda Lobley, Elizabeth L. Kyran, Emily O’Grady, Joshua Tram, Warren Zhou, Devindee Nugawela, Kym Pham Stewart, Reece Caldwell, Lia Papadopoulos, Ashley P. Ng, Alexander Dobrovic, Stephen B. Fox, Orla McNally, Jeremy D. Power, Tarek Meniawy, Teng Han Tan, Ian M. Collins, Oliver Klein, Stephen Barnett, Inger Olesen, Anne Hamilton, Oliver Hofmann, Sean Grimmond, Anthony T. Papenfuss, Clare L. Scott, Holly E. Barker
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-20 (2023)
Abstract Background Uterine leiomyosarcoma (uLMS) is a rare and aggressive gynaecological malignancy, with individuals with advanced uLMS having a five-year survival of 0.2) but only two samples had a CHORD score > 50%, one of which had a homozygous
Externí odkaz:
https://doaj.org/article/90697e9e0fe04ca583a35a4167337ba8
Autor:
Niklas Beyhoff, David Lohr, Arne Thiele, Vera Braun, Max Stahnke, Robert Klopfleisch, Oliver Klein, Anna Foryst-Ludwig, Ulrich Kintscher, Laura Schreiber
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss , Pp 100678- (2024)
Externí odkaz:
https://doaj.org/article/a8b69729c41c430da5739bd9124461a1
Autor:
Nathalie N Roschke, Karl H Hillebrandt, Dietrich Polenz, Oliver Klein, Joseph M G V Gassner, Johann Pratschke, Felix Krenzien, Igor M Sauer, Nathanael Raschzok, Simon Moosburner
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0297497 (2024)
BackgroundConsidering the expected increase in the elderly population and the growing emphasis on aging-related biomedical research, the demand for aged laboratory animals has surged, challenging established husbandry practices. Our objective was to
Externí odkaz:
https://doaj.org/article/736b7f9208884f70b0a0e0e156d05e83
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-20 (2022)
Abstract Over the past decade, immune checkpoint inhibitor (ICI) therapy has been established as the standard of care for many types of cancer, but the strategies employed have continued to evolve. Recently, much clinical focus has been on combining
Externí odkaz:
https://doaj.org/article/71ddc9e416cc475e9dbf1b2c9cd276ac
Autor:
Lena Peter, Désirée Jacqueline Wendering, Stephan Schlickeiser, Henrike Hoffmann, Rebecca Noster, Dimitrios Laurin Wagner, Ghazaleh Zarrinrad, Sandra Münch, Samira Picht, Sarah Schulenberg, Hanieh Moradian, Mir-Farzin Mashreghi, Oliver Klein, Manfred Gossen, Toralf Roch, Nina Babel, Petra Reinke, Hans-Dieter Volk, Leila Amini, Michael Schmueck-Henneresse
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 52-73 (2022)
Solid organ transplant (SOT) recipients receive therapeutic immunosuppression that compromises their immune response to infections and vaccines. For this reason, SOT patients have a high risk of developing severe coronavirus disease 2019 (COVID-19) a
Externí odkaz:
https://doaj.org/article/9113c01efc2341409d18184065607cd5
Autor:
Bart Neyns, Lisa Zimmer, Caroline Robert, Celeste Lebbe, Olivier Michielin, Omid Hamid, Anne Zaremba, Oliver Klein, Ruth Plummer, Joanna Mangana, Paolo A Ascierto, Katharina C Kähler, Georgina V Long, Ryan Sullivan, Grant A McArthur, Michael Weichenthal, Egle Ramelyte, Meghan J Mooradian, Douglas B Johnson, Alexander Shoushtari, Christian U Blank, Judith M Versluis, Prachi Bhave, Claudia Trojanello, Lu Si, Inderjit Mehmi, Tasnia Ahmed, Alexander M Menzies, Adnan Khattak, Severine Roy, Matteo S Carlino, Paul C Lorigan, Clara Allayous, Rachel Roberts-Thomson, Florentia Dimitriou, Kathleen Batty, Thierry Lesimple, Serigne N Lo, Alexandre Wicky, Richard Heywood, Lena Tran, Anna Stansfeld, Julia K Schwarze, Andrea Maurichi, Hui-Ling Yeoh, Mario Santinami, Andrew M Haydon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background Acral melanoma is a rare melanoma subtype with poor prognosis. Importantly, these patients were not identified as a specific subgroup in the landmark melanoma trials involving ipilimumab and the anti-programmed cell death protein-1 (PD-1)
Externí odkaz:
https://doaj.org/article/0b1c2b670e1e4ec1b95b97b6b085c47b
Autor:
Laura Golusda, Anja A. Kühl, Malte Lehmann, Katja Dahlke, Susanne Mueller, Philipp Boehm-Sturm, Jessica Saatz, Heike Traub, Joerg Schnorr, Christian Freise, Matthias Taupitz, Karina Biskup, Véronique Blanchard, Oliver Klein, Ingolf Sack, Britta Siegmund, Daniela Paclik
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Inflammatory bowel diseases (IBD) comprise mainly ulcerative colitis (UC) and Crohn´s disease (CD). Both forms present with a chronic inflammation of the (gastro) intestinal tract, which induces excessive changes in the composition of the associated
Externí odkaz:
https://doaj.org/article/992889cdd19647b3a55a38ebfa9858e0