Výsledky vyhledávání - "Oliver J. Semmes"

Site-Specific Intact N-Linked Glycopeptide Characterization of Prostate-Specific Membrane Antigen from Metastatic Prostate Cancer Cells

Autor: Stephen Mackay, Naomi L. Hitefield, Ian O. Oduor, Autumn B. Roberts, Tanya C. Burch, Raymond S. Lance, Tina D. Cunningham, Dean A. Troyer, Oliver J. Semmes, Julius O. Nyalwidhe

Publikováno v: ACS Omega. 7:29714-29727

The composition of N-linked glycans that are conjugated to the prostate-specific membrane antigen (PSMA) and their functional significance in prostate cancer progression have not been fully characterized. PSMA was isolated from two metastatic prostat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942d4653382662d33d5f9b4a7800d200
https://doi.org/10.1021/acsomega.2c02265

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Data from Human T-Cell Leukemia Virus I Tax Protein Sensitizes p53-Mutant Cells to DNA Damage

Autor: Gary M. Kupfer, Oliver J. Semmes, Moshe Khurgel, Allison M. Green, Valia T. Mihaylova

Mutations in p53 are a common cause of resistance of cancers to standard chemotherapy and, thus, treatment failure. Reports have shown that Tax, a human T-cell leukemia virus type I encoded protein that has been associated with genomic instability an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::857ca177c49b5070845de20f423a01f6
https://doi.org/10.1158/0008-5472.c.6496857

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Abstract 520: MYB exhibits racially disparate overexpression and clinicopathologic association in prostate cancer: significance as a predictor of biochemical recurrence

Autor: Mohammad Aslam Khan, Srijan Acharya, Shashi Anand, Fnu Sameeta, James E. Carter, Oliver J. Semmes, Dean A. Troyer, Seema Singh, Santanu Dasgupta, Ajay P. Singh

Publikováno v: Cancer Research. 82:520-520

Prostate cancer (PCa) is the most diagnosed non-cutaneous malignancy and the second leading cause of cancer-related death in American men. Significant racial disparities also exist in incidence and clinical outcome. African American (AA) men are near

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c5dbba2373e6deffb97cec68a4508925
https://doi.org/10.1158/1538-7445.am2022-520

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Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression

Autor: Julie V, Philley, Anbarasu, Kannan, Wenyi, Qin, Edward R, Sauter, Mitsuo, Ikebe, Kate L, Hertweck, Dean A, Troyer, Oliver J, Semmes, Santanu, Dasgupta

Publikováno v: Journal of cellular physiology. 231(6)

Mitochondria (mt) encoded respiratory complex-I (RCI) mutations and their pathogenicity remain largely unknown in prostate cancer (PCa). Little is known about the role of mtDNA loss on mt integrity in PCa. We determined mtDNA mutation in human and mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4bf5ec4b810e469d6558bdb8793df0b0
https://pubmed.ncbi.nlm.nih.gov/26530043

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Divergent subcellular locations of HTLV-I tax and Int-6: A contrast between in vitro protein-protein binding and intracellular protein colocalization

Autor: Francesca Diella, Robert Callahan, Oliver J. Semmes, Kuan-Teh Jeang, Dong-Yan Jin, Christine Neuveut

Publikováno v: Journal of Biomedical Science. 4:229-234

Protein-protein interactions define many important molecular and cellular processes in prokaryotic and eukaryotic biology. In trying to delineate the contact between two proteins, the yeast two-hybrid assay has emerged as a powerful technique. Comple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97017831fa6b4acdfc60bbc2bbd461a3
https://doi.org/10.1007/bf02253422

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Human T-cell Leukemia Virus Type I Tax Masks c-Myc Function through a cAMP-dependent Pathway

Autor: John Barrett, Oliver J. Semmes, Kuan-Teh Jeang, Chi V. Dang

Publikováno v: Journal of Biological Chemistry. 271:9730-9738

Human T-cell leukemia virus type I Tax is a pleiotropic gene regulator that functions through CREB/ATF- and NF-kappaB-mediated pathways. In most contexts, Tax is a potent gene activator. Here, we describe an unexpected finding of Myc repression by Ta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37422f1fc3f2ace53d24be7d48f73eff
https://doi.org/10.1074/jbc.271.16.9730

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Induction of Micronuclei by HTLV-I Tax: A Cellular Assay for Function

Autor: Oliver J. Semmes, Kuan-Teh Jeang, Franca Majone

Publikováno v: Virology. 193:456-459

Cellular chromosomal damage is ubiquitously seen in HTLV-I-transformed lymphocytes. It is also characteristic of cells that have been exposed to mutagens. A sensitive measurement for mutagen-induced DNA damage is the formation of micronuclei in treat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c4097f4c1de16133a7ceacab49381e
https://doi.org/10.1006/viro.1993.1145

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