Zobrazeno 1 - 10
of 237
pro vyhledávání: '"Oliver J. Müller"'
Autor:
Marie Noormalal, Nesrin Schmiedel, Tarik Bozoglu, Andrea Matzen, Susanne Hille, Dima Ibrahim Basha, Prithviraj Manohar Vijaya Shetty, Anja Wolf, Marcin Zaradzki, Rawa Arif, Thomas Pühler, Georg Lutter, Andreas H. Wagner, Christian Kupatt, Derk Frank, Norbert Frey, Anca Remes, Oliver J. Müller
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101163- (2024)
Rupture or dissection of thoracic aortic aneurysms is still the leading cause of death for patients diagnosed with Marfan syndrome. Inflammation and matrix digestion regulated by matrix metalloproteases (MMPs) play a major role in the pathological re
Externí odkaz:
https://doaj.org/article/49ac9d0be7fc467286fe61422e59094f
Autor:
Luis Daniel Hernandez Torres, Flavia Rezende, Eva Peschke, Olga Will, Jan-Bernd Hövener, Frauke Spiecker, Ümit Özorhan, Josephine Lampe, Ines Stölting, Zouhair Aherrahrou, Carsten Künne, Kristina Kusche-Vihrog, Urte Matschl, Susanne Hille, Ralf P. Brandes, Markus Schwaninger, Oliver J. Müller, Walter Raasch
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionThe development of cognitive dysfunction is not necessarily associated with diet-induced obesity. We hypothesized that cognitive dysfunction might require additional vascular damage, for example, in atherosclerotic mice.MethodsWe induced
Externí odkaz:
https://doaj.org/article/d4b6fd0e43c94446adef814c1470c76c
Autor:
Yi Li, Niklas Dörmann, Björn Brinschwitz, Melanie Kny, Elisa Martin, Kirsten Bartels, Ning Li, Priyanka Voori Giri, Stefan Schwanz, Michael Boschmann, Susanne Hille, Britta Fielitz, Tobias Wollersheim, Julius Grunow, Stephan B. Felix, Steffen Weber‐Carstens, Friedrich C. Luft, Oliver J. Müller, Jens Fielitz
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 4, Pp 1721-1736 (2023)
Abstract Background Sepsis‐induced intensive care unit‐acquired weakness (ICUAW) features profound muscle atrophy and attenuated muscle regeneration related to malfunctioning satellite cells. Transforming growth factor beta (TGF‐β) is involved
Externí odkaz:
https://doaj.org/article/4f3b327ad2d446c7ae036a28a5240cf3
Autor:
Thomas Puehler, Nina Sophie Pommert, Sandra Freitag-Wolf, Hatim Seoudy, Markus Ernst, Assad Haneya, Janarthanan Sathananthan, Stephanie L. Sellers, David Meier, Jan Schöttler, Oliver J. Müller, Mona Salehi Ravesh, Mohammed Saad, Derk Frank, Georg Lutter
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 5, p 1474 (2024)
Background. The significance of concomitant tricuspid regurgitation (TR) in the context of transcatheter aortic valve replacement (TAVR) remains unclear. This study aimed to analyze the severity of TR before and after TAVR with regard to short- and l
Externí odkaz:
https://doaj.org/article/7884a6ebcc32488e9c9fe99e02635566
Autor:
Anca Remes, Marie Noormalal, Nesrin Schmiedel, Norbert Frey, Derk Frank, Oliver J. Müller, Markus Graf
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Pathological remodeling of the extracellular matrix is a hallmark of cardiovascular disease. Abnormal fibrosis causes cardiac dysfunction by reducing ejection fraction and impairing electrical conductance, leading to arrhythmias. Hence, accu
Externí odkaz:
https://doaj.org/article/4517ff33e1e6403faa08f301033d0786
Autor:
Georg Lutter, Nina Sophie Pommert, Xiling Zhang, Jette Seiler, Monireh Saeid Nia, David Meier, Stephanie L. Sellers, Stanislav N. Gorb, Jan-Hinnerk Hansen, Hatim Seoudy, Oliver J. Müller, Mohammed Saad, Assad Haneya, Derk Frank, Thomas Puehler, Janarthanan Sathananthan
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17357 (2023)
Transcatheter pulmonary valve replacement is a minimally-invasive alternative treatment for right ventricular outflow tract dysfunction and has been rapidly evolving over the past years. Heart valve prostheses currently available still have major lim
Externí odkaz:
https://doaj.org/article/a2c614988af6405ca54c59ed0027d0bd
Autor:
Binh Y. Nguyen, Fangchao Zhou, Pablo Binder, Wei Liu, Susanne S. Hille, Xiaojing Luo, Min Zi, Hongyuan Zhang, Antony Adamson, Fozia Z. Ahmed, Sam Butterworth, Elizabeth J. Cartwright, Oliver J. Müller, Kaomei Guan, Elizabeth M. Fitzgerald, Xin Wang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 12 (2023)
Background Prolonged activation of angiotensin II is the main mediator that contributes to the development of heart diseases, so converting angiotensin II into angiotensin 1‐7 has emerged as a new strategy to attenuate detrimental effects of angiot
Externí odkaz:
https://doaj.org/article/0de15311822a4ff99e0f184b803b44a8
Autor:
Andrea Ruiz-Velasco, Rida Raja, Xinyi Chen, Haresh Ganenthiran, Namrita Kaur, Nasser hawimel o Alatawi, Jessica M. Miller, Riham R.E. Abouleisa, Qinghui Ou, Xiangjun Zhao, Oveena Fonseka, Xin Wang, Susanne S. Hille, Norbert Frey, Tao Wang, Tamer M.A. Mohamed, Oliver J. Müller, Elizabeth J. Cartwright, Wei Liu
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106970- (2023)
Summary: Despite the development of clinical treatments, heart failure remains the leading cause of mortality. We observed that p21-activated kinase 3 (PAK3) was augmented in failing human and mouse hearts. Furthermore, mice with cardiac-specific PAK
Externí odkaz:
https://doaj.org/article/0b1e474d4e224701832effe508afdc92
Autor:
Matthias Petersen, Nesrin Schmiedel, Franziska Dierck, Susanne Hille, Anca Remes, Frauke Senger, Inga Schmidt, Renate Lüllmann-Rauch, Oliver J. Müller, Derk Frank, Ashraf Y. Rangrez, Norbert Frey, Christian Kuhn
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Despite the identification of numerous molecular pathways modulating cardiac hypertrophy its pathogenesis is not completely understood. In this study we define an unexpected role for Fibin (“fin bud initiation factor homolog”) in cardiomyocyte hy
Externí odkaz:
https://doaj.org/article/6a575afc00444393a65dd76ec25bfb68
Publikováno v:
Pathogens, Vol 12, Iss 11, p 1301 (2023)
Cardiac-targeted transgene delivery offers new treatment opportunities for cardiovascular diseases, which massively contribute to global mortality. Restricted gene transfer to cardiac tissue might protect extracardiac organs from potential side-effec
Externí odkaz:
https://doaj.org/article/9e5e6aa8801e4f0e9963dc2c3c60c45f