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pro vyhledávání: '"Oliver J. Hills"'
Autor:
Oliver J. Hills, Chin W. Yong, Andrew J. Scott, Deirdre A. Devine, James Smith, Helen F. Chappell
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Mucoid Pseudomonas aeruginosa is a prevalent cystic fibrosis (CF) lung coloniser whose chronicity is associated with the formation of cation cross-linked exopolysaccharide (EPS) matrices, which form a biofilm that acts as a diffusion barrier
Externí odkaz:
https://doaj.org/article/4a10b0b06527409a9e34545558db7b73
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287191 (2023)
Intravenous gallium therapy is a non-antibiotic approach to limit Pseudomonas aeruginosa biofilm proliferation, by outcompeting iron for siderophore binding. Gallium therapy represents a viable therapeutic strategy for cystic fibrosis (CF) patients h
Externí odkaz:
https://doaj.org/article/e8dd7dfdeb8f4c2b9543e6ee2912e86e
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257026 (2021)
Mucoid Pseudomonas aeruginosa is a prevalent cystic fibrosis (CF) lung colonizer, producing an extracellular matrix (ECM) composed predominantly of the extracellular polysaccharide (EPS) alginate. The ECM limits antimicrobial penetration and, consequ
Externí odkaz:
https://doaj.org/article/e18b644651cc4c729ccd9e21e7dcada6
Publikováno v:
Bioorganic & Medicinal Chemistry. 72:116945
Chronic mucoid P. aeruginosa cystic fibrosis (CF) lung infections are associated with the development of a biofilm composed of anionic acetylated exopolysaccharide (EPS) alginate, electrostatically stabilised by extracellular Ca