Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Oliver J. Clarke"'
Autor:
Martin J. Parker, Oliver J. Clarke
Publikováno v:
Journal of Computational Chemistry. 30:621-630
Cross-β amyloid is implicated in over 20 human diseases. Experiments suggest that specific sequence elements within amyloidogenic proteins play a major role in seeding amyloid formation. Identifying these seeding sequences is important for rationali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8722463d0a5ce9a5496c95fe224ec82a
https://doi.org/10.1002/jcc.21085
https://doi.org/10.1002/jcc.21085
Autor:
Karen Smith, Leigh A. Madden, Robert Hudson, Magali Carcenac, Oliver J. Clarke, John Greenman, Ross W. Boyle, André Pèlegrin
Publikováno v:
British Journal of Cancer
A promising approach to increase the specificity of photosensitizers used in photodynamic therapy has been through conjugation to monoclonal antibodies (MAb) directed against tumour-associated antigens. Many of the conjugations performed to date have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa7e3060136522d06889e16faeb24b9
https://doi.org/10.1038/sj.bjc.6602517
https://doi.org/10.1038/sj.bjc.6602517
Publikováno v:
Bioconjugate Chemistry. 13:249-263
A novel method for conjugating porphyrins and related molecules to proteins has been developed. The method, which involves synthesizing porphyrins, chlorins, and bacteriochlorins bearing a single amine-reactive isothiocyanate group represents a facil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e17f07509e377c268c420ef2d440c8
https://doi.org/10.1021/bc015547x
https://doi.org/10.1021/bc015547x
Autor:
Sakthitharan Shanmugathasan, Oliver J. Clarke, Susanna J. Shaw, Alan G. Osborne, Christine Edwards, Ross W. Boyle
Publikováno v:
Journal of Porphyrins and Phthalocyanines. :575-581
A 13 C NMR spectral study of 29 arylporphyrin derivatives is presented. In all of the tetrasubstituted and trisubstituted compounds examined the α- and β-carbons exhibited the expected broadened signals. In complete contrast, the diphenylporphyrins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e22e931f5cb995c6880fc5b1fe980875
https://doi.org/10.1002/jpp.364
https://doi.org/10.1002/jpp.364
Autor:
Ross W. Boyle, Oliver J. Clarke
Publikováno v:
ChemInform. 29
A novel method for selectively synthesising 5,15-diphenylporphyrins bearing different substituents on the 5- and 15-phenyl rings is reported. It has been found that the presence of zinc acetate is necessary in the final step to ensure good yields of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f352f1398c7111498a1cf2cb7034a8cb
https://doi.org/10.1002/chin.199850142
https://doi.org/10.1002/chin.199850142
Autor:
Oliver J. Clarke, Ross W. Boyle
Publikováno v:
ChemInform. 31
meso-Phenylporphyrins bearing a single isothiocyanate group react efficiently under ambient conditions with primary amino groups on proteins and polystyrene resins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96d9a17e1d1dd93503d0a0868a1abcb0
https://doi.org/10.1002/chin.200006105
https://doi.org/10.1002/chin.200006105
Autor:
Martin J. Parker, Oliver J. Clarke
Publikováno v:
Journal of computational chemistry. 29(7)
Energy-based methods for calculating time-averaged peptide structures are important for rational peptide design, for defining local structure propensities in large protein chains, and for exploring the sequence determinants of amyloid formation. High
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176abd7de36d365d69ae6b05739306fe
https://pubmed.ncbi.nlm.nih.gov/18074345
https://pubmed.ncbi.nlm.nih.gov/18074345
Autor:
Oliver J. Clarke, Ross W. Boyle
Publikováno v:
Chemical Communications. :2231-2232
meso-Phenylporphyrins bearing a single isothiocyanate group react efficiently under ambient conditions with primary amino groups on proteins and polystyrene resins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::166706d63f8dacb5fbd2b18d56b1ec47
https://doi.org/10.1039/a906298j
https://doi.org/10.1039/a906298j
Autor:
Oliver J. Clarke, Ross W. Boyle
Publikováno v:
Tetrahedron Letters. 39:7167-7168
A novel method for selectively synthesising 5,15-diphenylporphyrins bearing different substituents on the 5- and 15-phenyl rings is reported. It has been found that the presence of zinc acetate is necessary in the final step to ensure good yields of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::907bedefc13a2a90f6e3a46951919e63
https://doi.org/10.1016/s0040-4039(98)01534-2
https://doi.org/10.1016/s0040-4039(98)01534-2
Autor:
Susanna J. Shaw, Alan G. Osborne, Sakthitharan Shanmugathasan, Ross W. Boyle, Oliver J. Clarke, Christine Edwards
Publikováno v:
Journal of Porphyrins and Phthalocyanines. 5:895-895
The original article to which this Erratum refers was published in The Journal of Porphyrins and Phthalocyanines 5(7) 2001, 575–581 In the above paper the following was omitted: Acknowledgements: The authors wish to thank the Wellcome Trust (049704
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::103fadebfd0ab8d95d44e51e9b065680
https://doi.org/10.1002/jpp.561
https://doi.org/10.1002/jpp.561