Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Oliver J Newsom"'
Autor:
Madeleine L Hart, Evan Quon, Anna-Lena BG Vigil, Ian A Engstrom, Oliver J Newsom, Kristian Davidsen, Pia Hoellerbauer, Samantha M Carlisle, Lucas B Sullivan
Publikováno v:
eLife, Vol 12 (2023)
The oxidative tricarboxylic acid (TCA) cycle is a central mitochondrial pathway integrating catabolic conversions of NAD +to NADH and anabolic production of aspartate, a key amino acid for cell proliferation. Several TCA cycle components are implicat
Externí odkaz:
https://doaj.org/article/b4116c4d572544a4a487e9aeabc9e789
Autor:
Madeleine L Hart, Evan Quon, Anna-Lena BG Vigil, Ian A Engstrom, Oliver J Newsom, Kristian Davidsen, Pia Hoellerbauer, Samantha M Carlisle, Lucas B Sullivan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b7513eed835b0d4a9677bf7edc82081
https://doi.org/10.7554/elife.78654.sa2
https://doi.org/10.7554/elife.78654.sa2
Autor:
Oliver J. Newsom, Lucas B. Sullivan
Publikováno v:
Cell metabolism. 34(11)
Metabolic disruption is a mainstay of cancer therapy, prompting research aimed at identifying novel metabolic targets. Despite strong effects observed in culture, three recent studies found pancreatic tumors are refractory to disruption of the metabo
Autor:
Madeleine L. Hart, Evan Quon, Anna-Lena B. G. Vigil, Ian A. Engstrom, Oliver J. Newsom, Kristian Davidsen, Pia Hoellerbauer, Samantha M. Carlisle, Lucas B. Sullivan
The oxidative tricarboxylic acid (TCA) cycle is a central mitochondrial pathway integrating catabolic conversions of NAD+ to NADH and anabolic production of aspartate, a key amino acid for cell proliferation. Several TCA cycle components are implicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce70c01283930b3e512261d5c777efe4
https://doi.org/10.1101/2022.03.14.484352
https://doi.org/10.1101/2022.03.14.484352
Autor:
Adam J. Kanack, Michael D. Olp, Oliver J. Newsom, Jamie B. Scaglione, David M. Gooden, Kevin McMahon, Brian C. Smith, K. Matthew Scaglione
Publikováno v:
Chembiochem
The ubiquitin ligase C-terminus of Hsc70 interacting protein (CHIP) is an important regulator of proteostasis. Despite playing an important role in maintaining proteostasis, little progress has been made in developing small molecules that regulate ub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994c4b72ac9c5b5bebfc318acbeb154d
https://europepmc.org/articles/PMC9016715/
https://europepmc.org/articles/PMC9016715/
Autor:
Ran Ming, Jamie B. Scaglione, Adam J. Kanack, Erik Soderblom, Anna Umano, Kanesha L. Travis, Yumei Wu, Oliver J. Newsom, Matthew G. Thompson, K. Matthew Scaglione
Publikováno v:
SSRN Electronic Journal.
Autor:
Paige K. Arnold, Benjamin T. Jackson, Katrina I. Paras, Julia S. Brunner, Madeleine L. Hart, Oliver J. Newsom, Sydney P. Alibeckoff, Jennifer Endress, Esther Drill, Lucas B. Sullivan, Lydia W. S. Finley
Publikováno v:
Nature
The tricarboxylic acid (TCA) cycle is a central hub of cellular metabolism, oxidizing nutrients to generate reducing equivalents for energy production and critical metabolites for biosynthetic reactions. Despite the importance of TCA cycle products f
Publikováno v:
Journal of Biological Chemistry. 293:2735-2743
The accumulation of misfolded proteins promotes protein aggregation and neuronal death in many neurodegenerative diseases. To counteract misfolded protein accumulation, neurons have pathways that recognize and refold or degrade aggregation-prone prot