Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Oliver J, Maclaren"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 1, p e1011752 (2024)
Near-term forecasting of infectious disease incidence and consequent demand for acute healthcare services can support capacity planning and public health responses. Despite well-developed scenario modelling to support the Covid-19 response, Aotearoa
Externí odkaz:
https://doaj.org/article/da499d7cb03647f4bffcaa8afd54f07b
Publikováno v:
Infectious Disease Modelling, Vol 8, Iss 1, Pp 212-227 (2023)
Prediction of the progression of an infectious disease outbreak is important for planning and coordinating a response. Differential equations are often used to model an epidemic outbreak's behaviour but are challenging to parameterise. Furthermore, t
Externí odkaz:
https://doaj.org/article/95268419feae4240b3ddb5dad3d0ae5c
Autor:
Matthew J Simpson, Oliver J Maclaren
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 9, p e1011515 (2023)
Interpreting data using mechanistic mathematical models provides a foundation for discovery and decision-making in all areas of science and engineering. Developing mechanistic insight by combining mathematical models and experimental data is especial
Externí odkaz:
https://doaj.org/article/61e25b63844646879d2494fa93988960
Autor:
Michael J. Plank, Shaun C. Hendy, Rachelle N. Binny, Giorgia Vattiato, Audrey Lustig, Oliver J. Maclaren
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Epidemiological models range in complexity from relatively simple statistical models that make minimal assumptions about the variables driving epidemic dynamics to more mechanistic models that include effects such as vaccine-derived and infe
Externí odkaz:
https://doaj.org/article/0d198d2d94464e8b8110450e33617843
Publikováno v:
Epidemics, Vol 41, Iss , Pp 100657- (2022)
Aotearoa New Zealand experienced a wave of the Omicron variant of SARS-CoV-2 in 2022 with around 200 confirmed cases per 1000 people between January and May. Waning of infection-derived immunity means people become increasingly susceptible to re-infe
Externí odkaz:
https://doaj.org/article/64623f40490f4b6db1f56ca470602f8c
Autor:
Rachelle N. Binny, Audrey Lustig, Shaun C. Hendy, Oliver J. Maclaren, Kannan M. Ridings, Giorgia Vattiato, Michael J. Plank
Publikováno v:
PeerJ, Vol 10, p e14119 (2022)
During an epidemic, real-time estimation of the effective reproduction number supports decision makers to introduce timely and effective public health measures. We estimate the time-varying effective reproduction number, Rt, during Aotearoa New Zeala
Externí odkaz:
https://doaj.org/article/da9e2ca65cfa474daca52b8f03c5a0d2
Autor:
Rachelle N Binny, Patricia Priest, Nigel P French, Matthew Parry, Audrey Lustig, Shaun C Hendy, Oliver J Maclaren, Kannan M Ridings, Nicholas Steyn, Giorgia Vattiato, Michael J Plank
Publikováno v:
The Journal of Infectious Diseases. 227:9-17
BackgroundReverse transcription polymerase chain reaction (RT-PCR) tests are the gold standard for detecting recent infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Reverse transcription PCR sensitivity varies over the cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96bac33799380506958817f72f242633
https://doi.org/10.1093/infdis/jiac317
https://doi.org/10.1093/infdis/jiac317
Autor:
Matthew J. Simpson, Oliver J. Maclaren
Interpreting data using mechanistic mathematical models provides a founda-tion for discovery and decision-making in all areas of science and engineering. Key steps in using mechanistic mathematical models to interpret data include: (i) identifiabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3da273a7b8b53490534e8db965df6d67
https://doi.org/10.1101/2022.12.14.520367
https://doi.org/10.1101/2022.12.14.520367
Autor:
Oliver J Maclaren, Aimée Parker, Carmen Pin, Simon R Carding, Alastair J M Watson, Alexander G Fletcher, Helen M Byrne, Philip K Maini
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 7, p e1005688 (2017)
Our work addresses two key challenges, one biological and one methodological. First, we aim to understand how proliferation and cell migration rates in the intestinal epithelium are related under healthy, damaged (Ara-C treated) and recovering condit
Externí odkaz:
https://doaj.org/article/c51090bb4d624b438d20bf4f061ad52c
Autor:
Rachelle N, Binny, Patricia, Priest, Nigel P, French, Matthew, Parry, Audrey, Lustig, Shaun C, Hendy, Oliver J, Maclaren, Kannan M, Ridings, Nicholas, Steyn, Giorgia, Vattiato, Michael J, Plank
Publikováno v:
The Journal of infectious diseases.
Reverse transcriptase polymerase chain reaction (RT-PCR) tests are the gold standard for detecting recent infection with SARS-CoV-2. RT-PCR sensitivity varies over the course of an individual's infection, related to changes in viral load. Differences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22413011a15b95d70aaad475d009dc54
https://pubmed.ncbi.nlm.nih.gov/35876500
https://pubmed.ncbi.nlm.nih.gov/35876500