Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Oliver Hobert"'
Autor:
Chen Wang, Berta Vidal, Surojit Sural, Curtis Loer, G Robert Aguilar, Daniel M Merritt, Itai Antoine Toker, Merly C Vogt, Cyril C Cros, Oliver Hobert
Publikováno v:
eLife, Vol 13 (2024)
Mapping neurotransmitter identities to neurons is key to understanding information flow in a nervous system. It also provides valuable entry points for studying the development and plasticity of neuronal identity features. In the Caenorhabditis elega
Externí odkaz:
https://doaj.org/article/3f2a2035e4cc4f61876ece118b1cbd5e
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102901- (2024)
Summary: The auxin-inducible degron (AID) system is a broadly used tool for spatiotemporal and reversible control of protein depletion in multiple experimental model systems. AID2 technology relies on a synthetic ligand, 5-phenyl-indole-3-acetic acid
Externí odkaz:
https://doaj.org/article/0056373af4b14422866e862317bab7ec
Publikováno v:
eLife, Vol 12 (2024)
Visualizing synaptic connectivity has traditionally relied on time-consuming electron microscopy-based imaging approaches. To scale the analysis of synaptic connectivity, fluorescent protein-based techniques have been established, ranging from the la
Externí odkaz:
https://doaj.org/article/aa13e4c4750f4822a2d2c58d226d9f3c
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S113- (2023)
Externí odkaz:
https://doaj.org/article/ba105ede68c5463791fb459ad73588b2
Autor:
Molly B Reilly, Tessa Tekieli, Cyril Cros, G Robert Aguilar, James Lao, Itai Antoine Toker, Berta Vidal, Eduardo Leyva-Díaz, Abhishek Bhattacharya, Steven J Cook, Jayson J Smith, Ismar Kovacevic, Burcu Gulez, Robert W Fernandez, Elisabeth F Bradford, Yasmin H Ramadan, Paschalis Kratsios, Zhirong Bao, Oliver Hobert
Publikováno v:
PLoS Genetics, Vol 18, Iss 9, p e1010372 (2022)
Homeobox genes are prominent regulators of neuronal identity, but the extent to which their function has been probed in animal nervous systems remains limited. In the nematode Caenorhabditis elegans, each individual neuron class is defined by the exp
Externí odkaz:
https://doaj.org/article/fe4688294f674871a8ec6ca4b9adcc1d
Autor:
Berta Vidal, Burcu Gulez, Wen Xi Cao, Eduardo Leyva-Díaz, Molly B Reilly, Tessa Tekieli, Oliver Hobert
Publikováno v:
eLife, Vol 11 (2022)
Overarching themes in the terminal differentiation of the enteric nervous system, an autonomously acting unit of animal nervous systems, have so far eluded discovery. We describe here the overall regulatory logic of enteric nervous system differentia
Externí odkaz:
https://doaj.org/article/5dcfe6752925491280a7720334b5a04a
Autor:
Adam J Isabella, Eduardo Leyva-Díaz, Takuya Kaneko, Scott J Gratz, Cecilia B Moens, Oliver Hobert, Kate O’Connor-Giles, Rajan Thakur, HaoSheng Sun
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 8 (2021)
Externí odkaz:
https://doaj.org/article/74cb6f13377945e7a49b140c4ff6ec41
Autor:
Emily G Berghoff, Lori Glenwinkel, Abhishek Bhattacharya, HaoSheng Sun, Erdem Varol, Nicki Mohammadi, Amelia Antone, Yi Feng, Ken Nguyen, Steven J Cook, Jordan F Wood, Neda Masoudi, Cyril C Cros, Yasmin H Ramadan, Denise M Ferkey, David H Hall, Oliver Hobert
Publikováno v:
eLife, Vol 10 (2021)
Many neuronal identity regulators are expressed in distinct populations of cells in the nervous system, but their function is often analyzed only in specific isolated cellular contexts, thereby potentially leaving overarching themes in gene function
Externí odkaz:
https://doaj.org/article/e7ee36d6cc2944a39f18085f7d66c34d
Autor:
Lori Glenwinkel, Seth R Taylor, Kasper Langebeck-Jensen, Laura Pereira, Molly B Reilly, Manasa Basavaraju, Ibnul Rafi, Eviatar Yemini, Roger Pocock, Nenad Sestan, Marc Hammarlund, David M Miller III, Oliver Hobert
Publikováno v:
eLife, Vol 10 (2021)
The generation of the enormous diversity of neuronal cell types in a differentiating nervous system entails the activation of neuron type-specific gene batteries. To examine the regulatory logic that controls the expression of neuron type-specific ge
Externí odkaz:
https://doaj.org/article/af7e725ca0754a56a5647a1273beb41c
Autor:
Dylan P. Rahe, Oliver Hobert
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 7, Pp 2287-2302 (2019)
Ectopic expression of master regulatory transcription factors can reprogram the identity of specific cell types. The effectiveness of such induced cellular reprogramming is generally greatly reduced if the cellular substrates are fully differentiated
Externí odkaz:
https://doaj.org/article/a6fdca73e30e47768103c4cb2d4b6aab