Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Oliver Hilsenbeck"'
Autor:
Simon Hastreiter, Stavroula Skylaki, Dirk Loeffler, Andreas Reimann, Oliver Hilsenbeck, Philipp S. Hoppe, Daniel L. Coutu, Konstantinos D. Kokkaliaris, Michael Schwarzfischer, Konstantinos Anastassiadis, Fabian J. Theis, Timm Schroeder
Publikováno v:
Stem Cell Reports, Vol 11, Iss 1, Pp 58-69 (2018)
Summary: Embryonic stem cells (ESCs) display heterogeneous expression of pluripotency factors such as Nanog when cultured with serum and leukemia inhibitory factor (LIF). In contrast, dual inhibition of the signaling kinases GSK3 and MEK (2i) convert
Externí odkaz:
https://doaj.org/article/9562e4e013e74333b15588cca58c4372
Autor:
Hideaki Nakajima, Philip Dettinger, James S. Chavez, Nouraiz Ahmed, Germán Camargo Ortega, Eric M. Pietras, Timm Schroeder, Philipp S. Hoppe, Tobias Kull, Dirk Loeffler, Oliver Hilsenbeck, Yang Zhang, Martin Etzrodt
Publikováno v:
Journal of Experimental Medicine, 219 (1)
Transcription factors (TFs) regulate cell fates, and their expression must be tightly regulated. Autoregulation is assumed to regulate many TFs' own expression to control cell fates. Here, we manipulate and quantify the (auto)regulation of PU.1, a TF
Autor:
Nouraiz, Ahmed, Leo, Kunz, Philipp S, Hoppe, Dirk, Loeffler, Martin, Etzrodt, Germán Camargo, Ortega, Oliver, Hilsenbeck, Konstantinos, Anastassiadis, Timm, Schroeder
Publikováno v:
Stem Cell Reports
Summary The transcription factor (TF) GATA2 plays a key role in organ development and cell fate control in the central nervous, urogenital, respiratory, and reproductive systems, and in primitive and definitive hematopoiesis. Here, we generate a knoc
Autor:
Ivan Martin, Fabian Rudolf, Paul Bourgine, Oliver Hilsenbeck, Weijia Wang, Timm Schroeder, Dirk Loeffler, Alois Hopf
Publikováno v:
Blood. 131:1425-1429
Keeping track of individual cell identifications is imperative to the study of dynamic single-cell behavior over time. Highly motile hematopoietic stem and progenitor cells (HSPCs) migrate quickly and do not adhere, and thus must be imaged very frequ
Publikováno v:
Nature Biotechnology. 34:1137-1144
Continuous analysis of single cells, over several cell divisions and for up to weeks at a time, is crucial to deciphering rare, dynamic and heterogeneous cell responses, which would otherwise be missed by population or single-cell snapshot analysis.
Autor:
Arne Wehling, Konstantinos D. Kokkaliaris, Florin Schneiter, Max Endele, Philipp S. Hoppe, Timm Schroeder, Yang Zhang, Oliver Hilsenbeck, Dirk Loeffler, Niklas Müller-Bötticher
Publikováno v:
Nature 573, 426-429 (2019)
Haematopoietic stem cells self-renew and differentiate into all blood lineages throughout life, and can repair damaged blood systems upon transplantation. Asymmetric cell division has previously been suspected to be a regulator of haematopoietic-stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae77f4336d908002c92ad7dc9c5a1ce
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=56853
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=56853
Autor:
Nouraiz Ahmed, Dirk Loeffler, Philipp S. Hoppe, Konstantinos D. Kokkaliaris, Jörg Stelling, Timm Schroeder, Claus Nerlov, Hans-Michael Kaltenbach, Stavroula Skylaki, Oliver Hilsenbeck, Martin Etzrodt
Publikováno v:
Blood, 133 (8)
The molecular mechanisms governing the transition from hematopoietic stem cells (HSCs) to lineage-committed progenitors remain poorly understood. Transcription factors (TFs) are powerful cell intrinsic regulators of differentiation and lineage commit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4516b7f8c1ef18bb6c941ec73f48e66
https://doi.org/10.1182/blood-2018-02-832998
https://doi.org/10.1182/blood-2018-02-832998
Autor:
Konstantinos D. Kokkaliaris, Adam Filipczyk, Felix Buggenthin, Eleni Skylaki, Timm Schroeder, Justin Feigelman, Bernhard Schauberger, Max Endele, Michael Strasser, Carsten Marr, Dirk Loeffler, Oliver Hilsenbeck, Martin Etzrodt, Philipp S. Hoppe, Fabian J. Theis, Michael Schwarzfischer, Stavroula Skylaki, Jan Krumsiek, Adrianus J J van den Berg, Simon Hastreiter
Publikováno v:
Nature Biotechnology. 34:703-706
Software tools for single-cell tracking and quantification of cellular and molecular properties
Autor:
Fabian J. Theis, Andreas Reimann, Dirk Loeffler, Simon Hastreiter, Daniel L. Coutu, Konstantinos D. Kokkaliaris, Oliver Hilsenbeck, Philipp S. Hoppe, Stavroula Skylaki, Michael Schwarzfischer, Konstantinos Anastassiadis, Timm Schroeder
Publikováno v:
Stem Cell Reports, 10
Stem Cell Reports, Vol 11, Iss 1, Pp 58-69 (2018)
Stem Cell Reports
Stem Cell Rep. 10, 58-69 (2018)
Stem Cell Reports, Vol 11, Iss 1, Pp 58-69 (2018)
Stem Cell Reports
Stem Cell Rep. 10, 58-69 (2018)
Summary Embryonic stem cells (ESCs) display heterogeneous expression of pluripotency factors such as Nanog when cultured with serum and leukemia inhibitory factor (LIF). In contrast, dual inhibition of the signaling kinases GSK3 and MEK (2i) converts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23235229bc63a0cf96dd32b7101a6274
Autor:
Dirk Loeffler, Sotiris Dimopoulos, Fabian J. Theis, Simon Hastreiter, Timm Schroeder, Carsten Marr, Oliver Hilsenbeck, Michael Schwarzfischer
Publikováno v:
Bioinformatics, 33 (13)
Bioinformatics 33, 2020-2028 (2017)
Bioinformatics 33, 2020-2028 (2017)
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Bioinformatics, 33 (13)
ISSN:1367-4803
ISSN:1460-2059
Bioinformatics, 33 (13)
ISSN:1367-4803
ISSN:1460-2059
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff635f69eca34c6de16b608c2e29786
https://hdl.handle.net/20.500.11850/191262
https://hdl.handle.net/20.500.11850/191262