Výsledky vyhledávání - "Oliver Hamaker"

Akademický článek

Targeting two distinct epitopes on human CD73 with a bispecific antibody improves anticancer activity

Autor: Henrik J Ditzel, Christa E Müller, Odd L Gammelgaard, Mikkel G Terp, Christian Renn, Aran F Labrijn, Oliver Hamaker, Aaraby Y Nielsen, Henriette Vever, Soren WK Hansen, Morten F Gjerstorff, Paul WHI Parren

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)

Background Immunosuppressive extracellular adenosine is generated by the enzymatic activity of CD73. In preclinical models, antibodies (Abs) targeting different epitopes on CD73 exert anticancer activity through distinct mechanisms such as inhibition

Externí odkaz: https://doaj.org/article/545f0eb7e81a46de9104ffcb29d1c784

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Targeting two distinct epitopes on human CD73 with a bispecific antibody improves anticancer activity

Autor: Odd L Gammelgaard, Mikkel G Terp, Christian Renn, Aran F Labrijn, Oliver Hamaker, Aaraby Y Nielsen, Henriette Vever, Soren WK Hansen, Morten F Gjerstorff, Christa E Müller, Paul WHI Parren, Henrik J Ditzel

Publikováno v: Journal for ImmunoTherapy of Cancer, 10(9). BMJ PUBLISHING GROUP

BackgroundImmunosuppressive extracellular adenosine is generated by the enzymatic activity of CD73. In preclinical models, antibodies (Abs) targeting different epitopes on CD73 exert anticancer activity through distinct mechanisms such as inhibition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae93beea27221f5e2380b2fabc47370
https://pubmed.ncbi.nlm.nih.gov/36096528

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