Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Oliver Dittrich-Breiholz"'
Autor:
Antonella L. Bastone, Violetta Dziadek, Philipp John-Neek, Friederike Mansel, Jenni Fleischauer, Eric Agyeman-Duah, Dirk Schaudien, Oliver Dittrich-Breiholz, Adrian Schwarzer, Axel Schambach, Michael Rothe
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 515-533 (2023)
Safety assessment in retroviral vector-mediated gene therapy remains challenging. In clinical trials for different blood and immune disorders, insertional mutagenesis led to myeloid and lymphoid leukemia. We previously developed the In Vitro Immortal
Externí odkaz:
https://doaj.org/article/4d961949250f4d17b1e74ea409031a0e
Autor:
Nicole Huge, Thea Reinkens, Reena Buurman, Maria Sandbothe, Anke Bergmann, Hannah Wallaschek, Beate Vajen, Amelie Stalke, Melanie Decker, Marlies Eilers, Vera Schäffer, Oliver Dittrich-Breiholz, Engin Gürlevik, Florian Kühnel, Brigitte Schlegelberger, Thomas Illig, Britta Skawran
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background In hepatocellular carcinoma (HCC), histone deacetylases (HDACs) are frequently overexpressed. This results in chromatin compaction and silencing of tumor-relevant genes and microRNAs. Modulation of microRNA expression is a potenti
Externí odkaz:
https://doaj.org/article/3da413d23a3548bfa6c3093759f16cd4
Autor:
Katharina Streich, Margarethe Smoczek, Jan Hegermann, Oliver Dittrich-Breiholz, Melanie Bornemann, Anja Siebert, Andre Bleich, Manuela Buettner
Publikováno v:
Journal of Advanced Research, Vol 24, Iss , Pp 291-300 (2020)
In obesity, increased dietary lipids are taken up and transported by the lymphatic systems into the circulatory system. Increased fat accumulation results in impairments in the lymph fluid and lymph node (LN) atrophy. LNs filter the lymph fluid for f
Externí odkaz:
https://doaj.org/article/0216ea40159d434c9a462f5d5cf6e8b7
Autor:
Georgia Papadogianni, Inga Ravens, Ahmed Hassan, Oliver Dittrich-Breiholz, Günter Bernhardt, Hristo Georgiev
Publikováno v:
Biochemistry and Biophysics Reports, Vol 28, Iss , Pp 101163- (2021)
Invariant natural killer T (iNKT) cells develop in thymus before emigrating and settling peripheral tissues and organs. In contrast to regular naïve T cells, most iNKT cells do not continuously recirculate but are rather sessile and can adopt phenot
Externí odkaz:
https://doaj.org/article/32a7c5dcb434415db41314df195beb28
Autor:
Anton Selich, Katharina Zimmermann, Michel Tenspolde, Oliver Dittrich-Breiholz, Constantin von Kaisenberg, Axel Schambach, Michael Rothe
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract Background Mesenchymal stromal cells (MSCs) are used in over 800 clinical trials mainly due to their immune inhibitory activity. Umbilical cord (UC), the second leading source of clinically used MSCs, is usually cut in small tissue pieces. S
Externí odkaz:
https://doaj.org/article/e1b2a8867c56449689cd3a4f7f714c44
Autor:
Talke F. zur Bruegge, Andrea Liese, Sören Donath, Stefan Kalies, Maike Kosanke, Oliver Dittrich-Breiholz, Sandra Czech, Verena N. Bauer, André Bleich, Manuela Buettner
Publikováno v:
Stem Cells International, Vol 2021 (2021)
In recent years, stem cell-derived organoids have become a cell culture standard that is widely used for studying various scientific issues that were previously investigated through animal experiments and using common tumor cell lines. After their in
Externí odkaz:
https://doaj.org/article/c658cf2180534c15b46d8822f951e304
Autor:
Georgia Papadogianni, Inga Ravens, Oliver Dittrich-Breiholz, Günter Bernhardt, Hristo Georgiev
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Invariant natural killer T (iNKT) cells represent a subclass of T cells possessing a restricted repertoire of T cell receptors enabling them to recognize lipid derived ligands. iNKT cells are continuously generated in thymus and differentiate into th
Externí odkaz:
https://doaj.org/article/acbd3d85c4dd4068b4347fdf31881ceb
Autor:
Kirill Kreimann, Mi-Sun Jang, Song Rong, Robert Greite, Sibylle von Vietinghoff, Roland Schmitt, Jan Hinrich Bräsen, Lena Schiffer, Jessica Gerstenberg, Vijith Vijayan, Oliver Dittrich-Breiholz, Li Wang, Christian M. Karsten, Wilfried Gwinner, Hermann Haller, Stephan Immenschuh, Faikah Gueler
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Ischemia reperfusion injury (IRI) is linked with inflammation in kidney transplantation (ktx). The chemokine CXCL13, also known as B lymphocyte chemoattractant, mediates recruitment of B cells within follicles of lymphoid tissues and has recently bee
Externí odkaz:
https://doaj.org/article/b45660c9e05a4c32859baba53d849352
Autor:
Christoph Lipps, Franziska Klein, Tom Wahlicht, Virginia Seiffert, Milada Butueva, Jeannette Zauers, Theresa Truschel, Martin Luckner, Mario Köster, Roderick MacLeod, Jörn Pezoldt, Jochen Hühn, Qinggong Yuan, Peter Paul Müller, Henning Kempf, Robert Zweigerdt, Oliver Dittrich-Breiholz, Thomas Pufe, Rainer Beckmann, Wolf Drescher, Jose Riancho, Carolina Sañudo, Thomas Korff, Bertram Opalka, Vera Rebmann, Joachim R. Göthert, Paula M. Alves, Michael Ott, Roland Schucht, Hansjörg Hauser, Dagmar Wirth, Tobias May
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Personalised medicine requires cell cultures from defined genetic backgrounds, but providing sufficient numbers of cells is a challenge. Here the authors develop gene cocktails to expand primary cells from a variety of different tissues and species,
Externí odkaz:
https://doaj.org/article/e9ef9c4a20664d78b68d4039733b3449
Autor:
Lars Brodowski, Bianca Schröder-Heurich, Sandra von Hardenberg, Katja Richter, Constantin S. von Kaisenberg, Oliver Dittrich-Breiholz, Nadia Meyer, Thilo Dörk, Frauke von Versen-Höynck
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5320 (2021)
Preeclampsia is associated with an increased cardiovascular morbidity of mother and offspring, thus contributing to a substantial burden in women and children’s health. It has been proven that endothelial progenitor cell (EPC) numbers and functiona
Externí odkaz:
https://doaj.org/article/f8c1a33f0d9149fb8289ddb02d6b16fe