Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Oliver DK Maddocks"'
Autor:
Bernadette Carroll, Dorothea Maetzel, Oliver DK Maddocks, Gisela Otten, Matthew Ratcliff, Graham R Smith, Elaine A Dunlop, João F Passos, Owen Richard Davies, Rudolf Jaenisch, Andrew R Tee, Sovan Sarkar, Viktor I Korolchuk
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/6b2cf351d8cb4f19aed05575781ae9dc
Autor:
Sofie Deschoemaeker, Giusy Di Conza, Sergio Lilla, Rosa Martín‐Pérez, Daniela Mennerich, Lise Boon, Stefanie Hendrikx, Oliver DK Maddocks, Christian Marx, Praveen Radhakrishnan, Hans Prenen, Martin Schneider, Johanna Myllyharju, Thomas Kietzmann, Karen H Vousden, Sara Zanivan, Massimiliano Mazzone
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 10, Pp 1350-1365 (2015)
Abstract Overcoming resistance to chemotherapy is a major challenge in colorectal cancer (CRC) treatment, especially since the underlying molecular mechanisms remain unclear. We show that silencing of the prolyl hydroxylase domain protein PHD1, but n
Externí odkaz:
https://doaj.org/article/a3a9d3f5c75441d39d7785a441a85e40
Autor:
Bernadette Carroll, Dorothea Maetzel, Oliver DK Maddocks, Gisela Otten, Matthew Ratcliff, Graham R Smith, Elaine A Dunlop, João F Passos, Owen R Davies, Rudolf Jaenisch, Andrew R Tee, Sovan Sarkar, Viktor I Korolchuk
Publikováno v:
eLife, Vol 5 (2016)
The mammalian target of rapamycin complex 1 (mTORC1) is the key signaling hub that regulates cellular protein homeostasis, growth, and proliferation in health and disease. As a prerequisite for activation of mTORC1 by hormones and mitogens, there fir
Externí odkaz:
https://doaj.org/article/6984fb5071a4478b8cce115a8801a2ad