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pro vyhledávání: '"Oliver Couture"'
Autor:
Shivang Shah, Elisha Pendleton, Oliver Couture, Mustafa Broachwalla, Teresa Kusper, Lauren A.C. Alt, J. Fay Michael, Nalini Chandar
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100920- (2021)
In order to understand the role of the p53 tumor suppressor gene in microRNA expression during osteoblast differentiation, we used a screen to identify microRNAs that were altered in a p53-dependent manner. MicroRNAs from MC3T3-E1 preosteoblasts were
Externí odkaz:
https://doaj.org/article/894c5e145c6b4777855f9a79d4eed578
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e82494 (2013)
The tumor suppressor gene p53 is involved in a variety of cellular activities such as cellular stress responses, cell cycle regulation and differentiation. In our previous studies we have shown p53's transcription activating role to be important in o
Externí odkaz:
https://doaj.org/article/12cf636a00294535821e2f1e17c5e348
Autor:
Elisha Pendleton, Shivang Shah, Oliver Couture, Teresa Kusper, Mustafa Broachwalla, Lauren Alt, Michael Fay, Nalini Chandar
Publikováno v:
Cancer Research. 79:1796-1796
We have previously shown a role for tumor suppressor gene p53 in the transcriptional activation of several bone-specific genes in osteoblast differentiation. In this study, we used a screen for microRNAs to look for ones that were p53 dependent and d
Autor:
Grant Reed, Emily Hays, Janete Guardia, Sandeep Lakhan, Nalini Chandar, Oliver Couture, Hankui Chen
Publikováno v:
Biochemical and Biophysical Research Communications. 430:370-374
While Mdm2 is an important negative regulator of the p53 tumor suppressor, it also possesses p53-independent functions in cellular differentiation processes. Mdm2 expression is alternatively regulated by two P1 and P2 promoters. In this study we show
Publikováno v:
International Journal of Biological Sciences, Vol 3, Iss 3, Pp 132-152 (2007)
The past five years have seen a tremendous rise in porcine transcriptomic data. Available porcine Expressed Sequence Tags (ESTs) have expanded greatly, with over 623,000 ESTs deposited in Genbank. ESTs have been used to expand the pig-human comparati
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 11, p e82494 (2013)
PLoS ONE, Vol 8, Iss 11, p e82494 (2013)
The tumor suppressor gene p53 is involved in a variety of cellular activities such as cellular stress responses, cell cycle regulation and differentiation. In our previous studies we have shown p53's transcription activating role to be important in o
Publikováno v:
Cancer Research. 73:5438-5438
The tumor repressor gene, p53, is involved in a variety of cellular activities ranging from stress, differentiation and cell cycle regulation. In our previous studies we have shown p53’s transcription activating role to be important in osteoblast d