Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Oliver Cooper"'
Autor:
Kyle J. Connolly, Juliette Margaria, Erika Di Biase, Oliver Cooper, Penelope J. Hallett, Ole Isacson
Publikováno v:
Cells, Vol 12, Iss 21, p 2564 (2023)
Tightly regulated and highly adaptive lipid metabolic and transport pathways are critical to maintaining brain cellular lipid homeostasis and responding to lipid and inflammatory stress to preserve brain function and health. Deficits in the lipid han
Externí odkaz:
https://doaj.org/article/7a93c32a9bb34f7aab6684bf664fee10
Publikováno v:
Cell Reports, Vol 7, Iss 6, Pp 1755-1761 (2014)
To determine the long-term health and function of transplanted dopamine neurons in Parkinson’s disease (PD) patients, the expression of dopamine transporters (DATs) and mitochondrial morphology were examined in human fetal midbrain cellular transpl
Externí odkaz:
https://doaj.org/article/0033d5d203cb4d88a5fcd2fa7b3951de
Autor:
Laurie H. Sanders, Josée Laganière, Oliver Cooper, Sally K. Mak, B. Joseph Vu, Y. Anne Huang, David E. Paschon, Malini Vangipuram, Ramya Sundararajan, Fyodor D. Urnov, J. William Langston, Philip D. Gregory, H. Steve Zhang, J. Timothy Greenamyre, Ole Isacson, Birgitt Schüle
Publikováno v:
Neurobiology of Disease, Vol 62, Iss , Pp 381-386 (2014)
Parkinson's disease associated mutations in leucine rich repeat kinase 2 (LRRK2) impair mitochondrial function and increase the vulnerability of induced pluripotent stem cell (iPSC)-derived neural cells from patients to oxidative stress. Since mitoch
Externí odkaz:
https://doaj.org/article/d505d3408a924944819f08f5874cf168
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19926 (2011)
Neural stem cells (NSCs) lose their competency to generate region-specific neuronal populations at an early stage during embryonic brain development. Here we investigated whether epigenetic modifications can reverse the regional restriction of mouse
Externí odkaz:
https://doaj.org/article/4a992746dae340deab5b1aea2124ee27
Publikováno v:
Environmental Science and Pollution Research. 30:33018-33039
The high-Andean mountain of northern Chile host numerous water systems that is in risk due to increased mining activities. Total and dissolved Cd, Cr, Cu, Hg, Ni, Pb, Se, and Zn in water, and Cd, Cu, Fe, Ni, Pb, Zn, As, Mo, Al, and V in sediments of
Publikováno v:
The FEBS Journal.
Brain health requires circuits, cells and molecular pathways to adapt when challenged and to promptly reset once the challenge has resolved. Neurodegeneration occurs when adaptability becomes confined, causing challenges to overwhelm neural circuitry
Autor:
Oliver Cooper
Publikováno v:
Perspectives: Policy and Practice in Higher Education. 23:93-100
Gender equality is a high priority for UK universities with research showing that female academics do not progress at the same rate as their male counterparts. Research has been carried out to anal...
Autor:
Eduardo Perez-Torres, James M. Schumacher, Teresia Osborn, Maria Sundberg, Michele A. Moore, Anna-Liisa Brownell, Arnar Astradsson, Ole Isacson, Oliver Cooper, Michela Deleidi, Penelope J. Hallett, Roger D. Spealman, Gaynor A. Smith
Publikováno v:
Cell Stem Cell. 16(3):269-274
SummaryAutologous transplantation of patient-specific induced pluripotent stem cell (iPSC)-derived neurons is a potential clinical approach for treatment of neurological disease. Preclinical demonstration of long-term efficacy, feasibility, and safet
Publikováno v:
Cell Reports, Vol 7, Iss 6, Pp 1755-1761 (2014)
SummaryTo determine the long-term health and function of transplanted dopamine neurons in Parkinson’s disease (PD) patients, the expression of dopamine transporters (DATs) and mitochondrial morphology were examined in human fetal midbrain cellular
Publikováno v:
Dalton Trans.. 43:14275-14283
The reactivity of the uranium(IV) carbene complex [U(BIPMTMS)(Cl)(μ-Cl)2Li(THF)2] (1, BIPMTMS = {C(PPh2NSiMe3)2}) towards carbonyl and heteroallene substrates is reported. Reaction of 1 with benzophenone proceeds to give the metallo-Wittig terminal