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Publikováno v:
Cells, Vol 8, Iss 11, p 1341 (2019)
The MLL (mixed-lineage leukemia) gene, located on chromosome 11q23, is involved in chromosomal translocations in a subtype of acute leukemia, which represents approximately 10% of acute lymphoblastic leukemia and 2.8% of acute myeloid leukemia cases.
Externí odkaz:
https://doaj.org/article/5467738591e6455799c8b2591d8b7a23
Autor:
Catherine M. Green, Silvano Tosi, Daniela Moralli, Evgeny M. Makarov, Oliver Britten, Denise Ragusa
Publikováno v:
Cancer Reports
Background Haematological malignancies harbouring rearrangements of the KMT2A gene represent a unique subtype of leukaemia, with biphenotypic clinical manifestations, a rapid and aggressive onset, and a generally poor prognosis. Chromosomal transloca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94bcc83ac2469a771ba0a91891a2aa4
https://doi.org/10.1002/cnr2.1207
https://doi.org/10.1002/cnr2.1207
Publikováno v:
Cells, Vol 8, Iss 11, p 1341 (2019)
Cells
Cells
The MLL (mixed-lineage leukemia) gene, located on chromosome 11q23, is involved in chromosomal translocations in a subtype of acute leukemia, which represents approximately 10% of acute lymphoblastic leukemia and 2.8% of acute myeloid leukemia cases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7887f49f2e7d2cc02deefd42abb3226b
https://doi.org/10.3390/cells8111341
https://doi.org/10.3390/cells8111341