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of 9
pro vyhledávání: '"Oliver Boscheinen"'
Autor:
Steffen Zobel-Roos, Florian Vetter, Daniel Scheps, Marcus Pfeiffer, Matthias Gunne, Oliver Boscheinen, Jochen Strube
Publikováno v:
Processes; Volume 11; Issue 5; Pages: 1401
Optimizing or debottlenecking existing production plants is a challenging task. In this case study, an existing reversed phased chromatography polishing step for peptide purification was optimized with the help of a digital twin. The existing batch c
Publikováno v:
Journal of Separation Science. 46
Autor:
Steffen Zobel-Roos, Florian Vetter, Daniel Scheps, Marcus Pfeiffer, Matthias Gunne, Oliver Boscheinen, Jochen Strube
Publikováno v:
Processes; Volume 11; Issue 5; Pages: 1480
Many fundamental decisions in the process design of a separation task are conducted in an early stage where, unfortunately, process simulation does not have the highest priority. Subsequently, during the setup of the digital twin, dedicated experimen
Publikováno v:
Journal of Chromatography B. 1224:123735
Autor:
Jonas Koch, Daniel Scheps, Matthias Gunne, Oliver Boscheinen, Mathias Hafner, Christian Frech
Publikováno v:
Journal of separation scienceREFERENCES. 45(12)
The mechanistic modeling of preparative liquid chromatography is still a challenging task. Nonideal thermodynamic conditions may require activity coefficients for the mechanistic description of preparative chromatography. In this work, a chromatograp
Autor:
Oliver Boscheinen, Thomas Langer, Thomas Wendrich, Katja Kroll, Carsten Corvey, Werner Dittrich
Publikováno v:
Preparative Biochemistry & Biotechnology. 47:1008-1015
Glycosylation is one of the most complex post-translational modifications and may have significant influence on the proper function of the corresponding proteins. Bacteria and yeast are, because of easy handling and cost reasons, the most frequently
Autor:
Dieter Schmoll, Ursula Aschenbach, Oliver Boscheinen, Oliver Anderka, Janina Boyken, A. Batzer
Publikováno v:
Journal of Biological Chemistry. 283:31333-31340
Glucokinase (GK) is a key enzyme of glucose metabolism in liver and pancreatic beta-cells, and small molecule activators of GK (GKAs) are under evaluation for the treatment of type 2 diabetes. In liver, GK activity is controlled by the GK regulatory
Autor:
Oliver, Anderka, Janina, Boyken, Ursula, Aschenbach, Andreas, Batzer, Oliver, Boscheinen, Dieter, Schmoll
Publikováno v:
The Journal of biological chemistry. 283(46)
Glucokinase (GK) is a key enzyme of glucose metabolism in liver and pancreatic beta-cells, and small molecule activators of GK (GKAs) are under evaluation for the treatment of type 2 diabetes. In liver, GK activity is controlled by the GK regulatory
Publikováno v:
Biochemistry. 35(4)
The coupling of a DNA-binding protein to self-organized lipid monolayers is examined at the air-water interface by means of film balance techniques and epifluorescence microscopy. We used two recombinant species of the heat shock factor HSF24 which d