Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Oliver Borsch"'
Autor:
Maik Herbig, Karen Tessmer, Martin Nötzel, Ahsan Ahmad Nawaz, Tiago Santos-Ferreira, Oliver Borsch, Sylvia J. Gasparini, Jochen Guck, Marius Ader
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Biomedical research relies on identification and isolation of specific cell types using molecular biomarkers and sorting methods such as fluorescence or magnetic activated cell sorting. Labelling processes potentially alter the cells’ prop
Externí odkaz:
https://doaj.org/article/36def35017b545c59167dc1cb5ced157
Autor:
Sylvia J. Gasparini, Karen Tessmer, Miriam Reh, Stephanie Wieneke, Madalena Carido, Manuela Völkner, Oliver Borsch, Anka Swiersy, Marta Zuzic, Olivier Goureau, Thomas Kurth, Volker Busskamp, Günther Zeck, Mike O. Karl, Marius Ader
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 12 (2022)
Once human photoreceptors die, they do not regenerate, thus, photoreceptor transplantation has emerged as a potential treatment approach for blinding diseases. Improvements in transplant organization, donor cell maturation, and synaptic connectivity
Externí odkaz:
https://doaj.org/article/fe4bf4e4232c467ab4736faa8c84bb59
Autor:
Marcela Garita-Hernandez, Maruša Lampič, Antoine Chaffiol, Laure Guibbal, Fiona Routet, Tiago Santos-Ferreira, Sylvia Gasparini, Oliver Borsch, Giuliana Gagliardi, Sacha Reichman, Serge Picaud, José-Alain Sahel, Olivier Goureau, Marius Ader, Deniz Dalkara, Jens Duebel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
A challenge in cell therapy for photoreceptor degeneration is inducing the grafted cells to grow and maintain light sensitive outer segments. Here, the authors use optogenetics to circumvent this problem and restore visual function in blind mice.
Externí odkaz:
https://doaj.org/article/732d87294a534f1ab4fe044f1dcd7507
Autor:
Kaushikaram Subramanian, Martin Weigert, Oliver Borsch, Heike Petzold, Alfonso Garcia-Ulloa, Eugene W Myers, Marius Ader, Irina Solovei, Moritz Kreysing
Publikováno v:
eLife, Vol 8 (2019)
Rod photoreceptors of nocturnal mammals display a striking inversion of nuclear architecture, which has been proposed as an evolutionary adaptation to dark environments. However, the nature of visual benefits and the underlying mechanisms remains unc
Externí odkaz:
https://doaj.org/article/2a383c82c94d471fad04fe39824eaaf6
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Integration of transplanted photoreceptors into the host retina has been assumed as the underlying mechanism for vision improvement in pre-clinical studies. Here, the authors show that the majority of transplanted photoreceptors do not structurally i
Externí odkaz:
https://doaj.org/article/d130eae8679243cab91029177e74c7b8
Autor:
Elvir Becirovic, Sybille Böhm, Ong Nam Phuong Nguyen, Lisa Maria Riedmayr, Mirja Annika Koch, Elisabeth Schulze, Susanne Kohl, Oliver Borsch, Tiago Santos-Ferreira, Marius Ader, Stylianos Michalakis, Martin Biel
Publikováno v:
PLoS Genetics, Vol 12, Iss 1, p e1005811 (2016)
Point mutations in peripherin-2 (PRPH2) are associated with severe retinal degenerative disorders affecting rod and/or cone photoreceptors. Various disease-causing mutations have been identified, but the exact contribution of a given mutation to the
Externí odkaz:
https://doaj.org/article/61494f6ccda24c6c9488b5714c2fd72e
Publikováno v:
Neuromethods ISBN: 9781071627198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::511df77a3ffc27dd0eeb6074e638842f
https://doi.org/10.1007/978-1-0716-2720-4_5
https://doi.org/10.1007/978-1-0716-2720-4_5
Autor:
Patrick Heisterkamp, Oliver Borsch, Nundehui Diaz Lezama, Sylvia Gasparini, Adeeba Fathima, Livia S. Carvalho, Felix Wagner, Mike O. Karl, Michael Schlierf, Marius Ader
Publikováno v:
Experimental eye research 219, 109033 (2022). doi:10.1016/j.exer.2022.109033
Photoreceptor cell transplantation into the mouse retina has been shown to result in the transfer of cytoplasmic material between donor and host photoreceptors. Recently it has been found that this inter-photoreceptor material transfer process is lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09bc385ce0acf4610b251521f3c33d6
Autor:
Sylvia J. Gasparini, Karen Tessmer, Miriam Reh, Stephanie Wieneke, Madalena Carido, Manuela Völkner, Oliver Borsch, Anka Swiersy, Marta Zuzic, Olivier Goureau, Thomas Kurth, Volker Busskamp, Günther Zeck, Mike O. Karl, Marius Ader
Publikováno v:
J Clin Invest
Once human photoreceptors die, they do not regenerate, thus, photoreceptor transplantation has emerged as a potential treatment approach for blinding diseases. Improvements in transplant organization, donor cell maturation, and synaptic connectivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c420e2b104708c56ab0bf37ac1f0f4b
https://pubmed.ncbi.nlm.nih.gov/35482419
https://pubmed.ncbi.nlm.nih.gov/35482419
Autor:
Stephanie Wieneke, Thomas Kurth, Olivier Goureau, Sylvia J Gasparini, Manuela Voelkner, Marius Ader, Karen Tessmer, Madalena Carido, Mike O. Karl, Marta Zusic, Miriam Reh, Anka Swiersy, Oliver Borsch, Guenther Zeck, Volker Busskamp
SummaryOnce human photoreceptors die, they do not regenerate, thus photoreceptor transplantation has emerged as a potential treatment approach for blinding diseases. Improvements in transplant organization, donor cell maturation and synaptic connecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::feb883c20eaaa4ec5471b24049feed11
https://doi.org/10.1101/2021.08.26.457641
https://doi.org/10.1101/2021.08.26.457641