Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Oliver Bolte"'
Autor:
Ronald M. Bukowski, Olivier Rixe, James Lawrence Freddo, Robert J. Motzer, Gary R. Hudes, Oliver Bolte, George Wilding, Brian I. Rini, Paul Bycott, Peter C. Trask, M. Dror Michaelson, K. F. Liau, Sinil Kim
Publikováno v:
The Lancet Oncology. 8:975-984
Summary Background Axitinib (AG-013736) is an oral, potent, and selective inhibitor of vascular endothelial growth factor receptors 1, 2, and 3. We aimed to assess the activity and safety of axitinib in patients with metastatic renal-cell cancer who
Publikováno v:
Liebigs Annalen. 1996:1295-1299
Carbenes generated by metal-catalyzed decomposition of diazo compounds 2 undergo a smooth cycloaddition to the CS bond of thioketenes 1; products 3 were characterized by spectroscopic means as well as an X-ray structural investigation of 3b. However,
Autor:
Benoit Baron, Hans Lentzen, Sandrine Marreaud, Heinz Zwierzina, Patrick Schöffski, Oliver Bolte, Pierre Fumoleau, Denis Lacombe, C Twelves, S Riggert, K. Wilhelm-Ogunbiyi, Mario Campone, M Herold
Publikováno v:
Annals of Oncology. 15:1816-1824
Aviscumine is an Escherichia coli-derived recombinant type II ribosome-inactivating protein with potent antitumor activity in vitro and in vivo. It is the recombinant counterpart of natural mistletoe lectin-I. The current study was performed to deter
Publikováno v:
Tetrahedron Letters. 39:529-532
Easily available 1,3-bis(silyl)allyl compounds react with epoxides under Lewis acid catalysis to give interesting synthetic building blocks. The course of reaction depends on the stabilization of cationic intermediates by the silicon β-effect.
Acral Necrosis after Inadequate Excessive Administration of Bleomycin in a Testicular Cancer Patient
Publikováno v:
Oncology Research and Treatment. 28:41-43
Background: Testicular cancer has a favorable prognosis in the majority of patients due to the excellent susceptibility to chemotherapy with cisplatin, etoposide and bleomycin (BEP), which is commonly administered over 3-4 cycles of treatment. Case R
Publikováno v:
The Journal of Organic Chemistry. 58:626-632
The reaction of functionalized oxiranes 1 with the sulfur- or silicon-stabilized anions 2 provides β-heteroatom-substituted γ,δ-unsaturated epoxides 5 with, for 5e,f, a trans C=C moiety. A cis compound 9 is obtained using acetylide anion 2c via 7
Publikováno v:
ChemInform. 24
Publikováno v:
ChemInform. 25
Reaction of dialkylthioketenes with tetracyanoethylene oxide yields dicyanomethylenethiiranes in a sequence involving [3 + 2] cycloaddition, cycloreversion and rearrangement. In contrast, a thioketene with a sulfide moiety reacts preferentially on th
Publikováno v:
ChemInform. 27
Publikováno v:
ChemInform. 29
Easily available 1,3-bis(silyl)allyl compounds react with epoxides under Lewis acid catalysis to give interesting synthetic building blocks. The course of reaction depends on the stabilization of cationic intermediates by the silicon β-effect.