Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Oliver Treeck"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5894 (2024)
There is evidence suggesting that endocrine interventions such as hormone replacement therapy and hormonal contraception can increase breast cancer (BC) risk. Sexual steroid hormones like estrogens have long been known for their adverse effects on BC
Externí odkaz:
https://doaj.org/article/32421759ec1f401596a2bb0f357dc689
Publikováno v:
Diagnostics, Vol 13, Iss 5, p 944 (2023)
Chemerin, a pleiotropic adipokine coded by the RARRES2 gene, has been reported to affect the pathophysiology of various cancer entities. To further approach the role of this adipokine in ovarian cancer (OC), intratumoral protein levels of chemerin an
Externí odkaz:
https://doaj.org/article/7877aed129774159820fbc4adad956e5
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 737 (2023)
The chemoattractant protein chemerin is protective in experimental hepatocellular carcinoma (HCC), and high expression in HCC tissues of Asian patients was related to a favorable prognosis. Studies from Asia found reduced expression of chemerin in HC
Externí odkaz:
https://doaj.org/article/7b549905de3e499c94729f242eb2c6ea
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3473 (2023)
BAMBI (bone morphogenetic protein and activin membrane-bound inhibitor) is a transmembrane pseudoreceptor structurally related to transforming growth factor (TGF)-β type 1 receptors (TGF-β1Rs). BAMBI lacks a kinase domain and functions as a TGF-β1
Externí odkaz:
https://doaj.org/article/7bb92d77bdbc400fa94c376dd54ccff9
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2503 (2022)
Polycystic ovary syndrome (PCOS) and endometriosis are frequent diseases of the female reproductive tract causing high morbidity as they can significantly affect fertility and quality of life. Adipokines are pleiotropic signaling molecules secreted b
Externí odkaz:
https://doaj.org/article/86b9a877036845e18d987405da0d9810
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Estrogen receptor β (ERβ) has been repeatedly suggested to play important roles in hormone-dependent cancer like in tumors of the breast, ovary or prostate. In this study, we intended to further elucidate its role in endometrial
Externí odkaz:
https://doaj.org/article/3c6b887aa21641f29697b80a8cfbf7fa
Autor:
Oliver Treeck, Florian Weber, Juergen Fritsch, Maciej Skrzypczak, Susanne Schüler-Toprak, Christa Buechler, Olaf Ortmann
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1727 (2022)
Accumulating evidence suggests that lncRNA DSCAM-AS1 acts tumor-promoting in various cancer entities. In breast cancer, DSCAM-AS1 was shown to be the lncRNA being most responsive to induction by estrogen receptor α (ERα). In this study, we examined
Externí odkaz:
https://doaj.org/article/371de88cfdc44447a40ab0b5debc609b
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background In ovarian cancer, the role of estrogen receptors (ERs), particularly of ERβ, being suggested as tumor suppressor in breast and prostate cancer, remains unclear. We examined the expression of nuclear and cytoplasmic ERβ in ovari
Externí odkaz:
https://doaj.org/article/91905a7011c8431283eff7205872b498
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Estrogen receptor (ER) β has been suggested to affect ovarian carcinogenesis. We examined the effects of four ERβ agonists on proliferation and gene expression of two ovarian cancer cell lines. Methods OVCAR-3 and OAW-42 ovarian
Externí odkaz:
https://doaj.org/article/7b464ad7385344daaa93fdf10e011622
Publikováno v:
Cells, Vol 9, Iss 11, p 2358 (2020)
Triple-negative breast cancer (TNBC) lacks estrogen receptor (ER) α, but the expression of estrogen receptors ERβ and G protein-coupled estrogen receptor 1 (GPER-1) is able to trigger estrogen-responsivity in TNBC. Estrogen signaling in TNBC can al
Externí odkaz:
https://doaj.org/article/a51bfdedb0a74b81a6881016bf311106