Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Oliver, Schanz"'
Autor:
Jenny Landsberg, Dominik Wolf, Peter Krawitz, Gottfried Baier, Peter Brossart, Oliver Schanz, Isabelle Cornez, Sowmya Parampalli Yajnanarayana, Friederike Sophie David, Sebastian Peer, Thomas Gruber, Annkristin Heine
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Casitas B lymphoma-b (Cbl-b) is a central negative regulator of cytotoxic T and natural killer (NK) cells and functions as an intracellular checkpoint in cancer. In particular, Th9 cells support mast cell activation, promote dendritic cell
Externí odkaz:
https://doaj.org/article/e4eebec671b74e7f85ca2ee40269a165
Autor:
Jan P. Böttcher, Oliver Schanz, Christoph Garbers, Anne Zaremba, Silke Hegenbarth, Christian Kurts, Marc Beyer, Joachim L. Schultze, Wolfgang Kastenmüller, Stefan Rose-John, Percy A. Knolle
Publikováno v:
Cell Reports, Vol 8, Iss 5, Pp 1318-1327 (2014)
Immune control of infections with viruses or intracellular bacteria relies on cytotoxic CD8+ T cells that use granzyme B (GzmB) for elimination of infected cells. During inflammation, mature antigen-presenting dendritic cells instruct naive T cells w
Externí odkaz:
https://doaj.org/article/1faa4c3286d149e591e9d48f7f359528
Autor:
Jan P. Böttcher, Oliver Schanz, Dirk Wohlleber, Zeinab Abdullah, Svenja Debey-Pascher, Andrea Staratschek-Jox, Bastian Höchst, Silke Hegenbarth, Jessica Grell, Andreas Limmer, Imke Atreya, Markus F. Neurath, Dirk H. Busch, Edgar Schmitt, Peter van Endert, Waldemar Kolanus, Christian Kurts, Joachim L. Schultze, Linda Diehl, Percy A. Knolle
Publikováno v:
Cell Reports, Vol 3, Iss 3, Pp 779-795 (2013)
Development of CD8+ T cell (CTL) immunity or tolerance is linked to the conditions during T cell priming. Dendritic cells (DCs) matured during inflammation generate effector/memory T cells, whereas immature DCs cause T cell deletion/anergy. We identi
Externí odkaz:
https://doaj.org/article/707c86f231ea47f7a294b44c348f41e4
Autor:
Oliver, Schanz, Isabelle, Cornez, Sowmya Parampalli, Yajnanarayana, Friederike Sophie, David, Sebastian, Peer, Thomas, Gruber, Peter, Krawitz, Peter, Brossart, Annkristin, Heine, Jenny, Landsberg, Gottfried, Baier, Dominik, Wolf
Publikováno v:
Journal for Immunotherapy of Cancer
Background Casitas B lymphoma-b (Cbl-b) is a central negative regulator of cytotoxic T and natural killer (NK) cells and functions as an intracellular checkpoint in cancer. In particular, Th9 cells support mast cell activation, promote dendritic cell
Autor:
Yasmin Majlesain, Heike Weighardt, Rieka Chijiiwa, Sevgi Can Cengiz, Oliver Schanz, Haruko Takeyama, Irmgard Förster
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 9
International Journal of Molecular Sciences, Vol 21, Iss 3189, p 3189 (2020)
Volume 21
Issue 9
International Journal of Molecular Sciences, Vol 21, Iss 3189, p 3189 (2020)
A diet rich in vegetables and fruit is generally considered healthy because of a high content of phytochemicals, vitamins, and fiber. The phytochemical indole-3-carbinol (I3C), a derivative of glucobrassicin, is sold as a dietary supplement promising
Autor:
Michael Blank, Marc Beyer, Günter Mayer, Eicke Latz, Oliver Schanz, Markus Funke, Heike Weighardt, Julia Siegl, Joachim L. Schultze, Kristian Händler, Lorenz Fülle, Anna Belen Erazo, Silvana K. Haßel, H. James Stunden, Irmgard Förster, Fabian Gondorf, Franziska Pfeiffer, Carsten Gröber, Friederike V. Opitz, Nancy Steiner
Publikováno v:
Molecular therapy 26(1), 95-104 (2018). doi:10.1016/j.ymthe.2017.10.005
Molecular Therapy
Molecular Therapy
The chemokine CCL17, mainly produced by dendritic cells (DCs) in the immune system, is involved in the pathogenesis of various inflammatory diseases. As a ligand of CCR4, CCL17 induces chemotaxis and facilitates T cell-DC interactions. We report the
Autor:
Christoph Garbers, Christian Kurts, Edgar Schmitt, Oliver Schanz, Silke Hegenbarth, Dirk Wohlleber, Michael Dudek, Tobias Bopp, Stefan Rose John, Percy A. Knolle, Jan P. Böttcher, Michaela Wittlich
Publikováno v:
Journal of Hepatology. 66:978-986
Background & Aims Liver sinusoidal endothelial cells (LSECs) are prominent liver-resident antigen (cross-)presenting cells. LSEC cross-priming of naive CD8 T cells does not require CD4 T cell help in contrast to priming by dendritic cells (DC) but le
Autor:
Lorenz Fülle, Heike Weighardt, Zeinab Abdullah, Anna Belen Erazo, Judith Alferink, Christian Henneberger, Oliver Schanz, Jan N. Hansen, Luca Radau, Irmgard Förster, Harald Neumann, Nina Offermann, Konrad Knöpper, Annett Halle, Fabian Gondorf, Björn Breithausen
Publikováno v:
Glia 66(10), 2246-2261 (2018). doi:10.1002/glia.23507
Glia
Glia
Chemokines are important signaling molecules in the immune and nervous system. Using a fluorescence reporter mouse model, we demonstrate that the chemokine CCL17, a ligand of the chemokine receptor CCR4, is produced in the murine brain, particularly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df86cc571e4121cf189ad16e4394051c
https://pub.dzne.de/record/140340
https://pub.dzne.de/record/140340
Autor:
Oliver Schanz, Marc Beyer, Stefan Rose-John, Silke Hegenbarth, Anne Zaremba, Wolfgang Kastenmüller, Christian Kurts, Joachim L. Schultze, Percy A. Knolle, Christoph Garbers, Jan P. Böttcher
Publikováno v:
Cell Reports, Vol 8, Iss 5, Pp 1318-1327 (2014)
Immune control of infections with viruses or intracellular bacteria relies on cytotoxic CD8(+) T cells that use granzyme B (GzmB) for elimination of infected cells. During inflammation, mature antigen-presenting dendritic cells instruct naive T cells
Autor:
Oliver Schanz, Markus Korkowski, Toru Maruyama, Thomas Haarmann-Stemmann, Charlotte Esser, Josef Abel, Julia Vorac, Dorthe von Smolinski, Jessica König, Irmgard Förster, Heike Weighardt, Haruko Takeyama, Tetsushi Mori, Joachim L. Schultze, Olga Brandstätter
Publikováno v:
Scientific Reports
As a sensor of polyaromatic chemicals the aryl hydrocarbon receptor (AhR) exerts an important role in immune regulation besides its requirement for xenobiotic metabolism. Transcriptional activation of AhR target genes is counterregulated by the AhR r