Výsledky vyhledávání - "Oliver, L. R."

Expanding the known structure space for RNA binding: a test of 2,5-diketopiperazine

Autor: Diego M. Arévalo, Viktoriya S. Anokhina, Oliver L. R. Swart, Benjamin L. Miller

Publikováno v: Org Biomol Chem

As the importance of RNA as a therapeutic target has become increasingly recognized, the need for new chemotypes able to bind RNA has grown in significance. We hypothesized that diketopiperazines (DKPs), common substructures in natural products and p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234ff991655559f30268110f2f09fa9e
https://doi.org/10.1039/d1ob01976g

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Allosteric inhibition of Acinetobacter baumannii ATP phosphoribosyltransferase by protein:dipeptide and protein:protein Interactions

Autor: Benjamin J. Read, Gemma Fisher, Oliver L. R. Wissett, Teresa F. G. Machado, John Nicholson, John B. O. Mitchell, Rafael G. da Silva

This work was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) (Grant BB/M010996/1) via EASTBIO Doctoral Training Partnership studentships to B.J.R. and G.F., and by the Engineering and Physical Sciences Research Counci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8f27fefe60c1f31613e0c53eee030d
https://hdl.handle.net/10023/26626

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Allosteric Inhibition of

Autor: Benjamin J, Read, Gemma, Fisher, Oliver L R, Wissett, Teresa F G, Machado, John, Nicholson, John B O, Mitchell, Rafael G, da Silva

Publikováno v: ACS infectious diseases. 8(1)

ATP phosphoribosyltransferase (ATPPRT) catalyzes the first step of histidine biosynthesis in bacteria, namely, the condensation of ATP and 5-phospho-α-d-ribosyl-1-pyrophosphate (PRPP) to generate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e4481bec9389a08bd62d7a85303a6d6a
https://pubmed.ncbi.nlm.nih.gov/34928596

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